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Hirotsugu Hino

Observed names: Hino Hirotsugu, Hino, Hirotsugu
ORCID: 0000-0001-7560-2442
Observed ORCID: 0000-0001-7560-2442
OpenAlex ID: A5056210683
Two Bistable Switches Govern M Phase Entry
2016 · Satoru Mochida, Scott Rata, et al. · Current Biology · 86
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Abemaciclib induces atypical cell death in cancer cells characterized by formation of cytoplasmic vacuoles derived from lysosomes
2020 · Hirotsugu Hino, Noriyoshi Iriyama, et al. · Cancer Science · 78
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The cyclin-dependent kinase 4/6 inhibitor, abemaciclib, exerts dose-dependent cytostatic and cytocidal effects and induces autophagy in multiple myeloma cells
2017 · Noriyoshi Iriyama, Hirotsugu Hino, et al. · Leukemia & lymphoma/Leukemia and lymphoma · 45
Comparison of autophagy inducibility in various tyrosine kinase inhibitors and their enhanced cytotoxicity via inhibition of autophagy in cancer cells in combined treatment with azithromycin
2020 · Hideki Tanaka, Hirotsugu Hino, et al. · Biochemistry and Biophysics Reports · 37
Vitamin K2 induces non-apoptotic cell death along with autophagosome formation in breast cancer cell lines
2019 · Shinsuke Miyazawa, Shota Moriya, et al. · Breast Cancer · 33
Azithromycin, a potent autophagy inhibitor for cancer therapy, perturbs cytoskeletal protein dynamics
2023 · Naoharu Takano, Masaki Hiramoto, et al. · British Journal of Cancer · 29
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Targeted disruption of GAK stagnates autophagic flux by disturbing lysosomal dynamics
2021 · Masaya Miyazaki, Masaki Hiramoto, et al. · International Journal of Molecular Medicine · 20
BRCA1 degradation in response to mitochondrial damage in breast cancer cells
2021 · Kana Miyahara, Naoharu Takano, et al. · Scientific Reports · 20
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Macrolide antibiotics enhance the antitumor effect of lansoprazole resulting in lysosomal membrane permeabilization‑associated cell death
2020 · Atsuo Takeda, Naoharu Takano, et al. · International Journal of Oncology · 20
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Fingolimod sensitizes EGFR wild‑type non‑small cell lung cancer cells to lapatinib or sorafenib and induces cell cycle arrest
2019 · Kohki Ota, Takashi Okuma, et al. · Oncology Reports · 17
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Amino acid starvation culture condition sensitizes EGFR-expressing cancer cell lines to gefitinib-mediated cytotoxicity by inducing atypical necroptosis
2018 · Yu Saito, Shota Moriya, et al. · International Journal of Oncology · 16
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FADS2 confers SCD1 inhibition resistance to cancer cells by modulating the ER stress response
2024 · Toshikatsu Ikeda, Yuki Katoh, et al. · Scientific Reports · 14
Age-related exacerbation of hematopoietic organ damage induced by systemic hyper-inflammation in senescence-accelerated mice
2021 · Tomonori Harada, Isao Tsuboi, et al. · Scientific Reports · 12
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Sequestosome 1 (p62) accumulation in breast cancer cells suppresses progesterone receptor expression via argonaute 2
2020 · Ayuka Yokota, Masaki Hiramoto, et al. · Biochemical and Biophysical Research Communications · 8
Inhibitor-1 and -2 of PP2A have preference between PP2A complexes
2015 · Hirotsugu Hino, Kaori Takaki, et al. · Biochemical and Biophysical Research Communications · 7
Imbalanced M1 and M2 Macrophage Polarization in Bone Marrow Provokes Impairment of the Hematopoietic Microenvironment in a Mouse Model of Hemophagocytic Lymphohistiocytosis
2022 · Miyuki Yuda, Shin Aizawa, et al. · Biological and Pharmaceutical Bulletin · 6
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Abemaciclib and Vacuolin-1 induce vacuole-like autolysosome formation – A new tool to study autophagosome-lysosome fusion
2022 · Yoshinori Tanaka, Hirotsugu Hino, et al. · Biochemical and Biophysical Research Communications · 5
Clarithromycin overcomes stromal cell-mediated drug resistance against proteasome inhibitors in myeloma cells via autophagy flux blockage leading to high NOXA expression
2023 · Shota Moriya, Hiromi Kazama, et al. · PLoS ONE · 4
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Ran and Calcineurin Can Participate Collaboratively in the Regulation of Spermatogenesis in Scallop
2012 · Hirotsugu Hino, Kana Arimoto, et al. · Marine Biotechnology · 4
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Cytonuclear Estrogen Receptor Alpha Regulates Proliferation and Migration of Endometrial Carcinoma Cells.
2021 · Mierxiati Saimi, Shota Moriya, et al. · PubMed · 3
Abemaciclib and Vacuolin-1 decrease aggregate-prone TDP-43 accumulation by accelerating autophagic flux
2024 · Yoshinori Tanaka, Lina Kozuma, et al. · Biochemistry and Biophysics Reports · 2
GAK antagonises ROCK-dependent regulation of actomyosin dynamics
2026 · Masaki Hiramoto, Naoharu Takano, et al. · Journal of Cell Science · 1
Cyclin-Dependent Kinase 4/6 Inhibitor Abemaciclib Exerts Dose-Dependent Cytostatic and Cytocidal Effects on Multiple Myeloma Cells Via Autophagy
2016 · Noriyoshi Iriyama, Hirotsugu Hino, et al. · Blood · 1
Serum Free Fatty Acid-Based Diagnostic Index for Cervical Cancer Including High-Risk HPV-Negative Cases: An Independent Validation Study
2026 · Yuki Katoh, Yosuke Fujii, et al. · Diagnostics
Technology and Utilization of the 3D Cell Culture Method
2025 · Atsuro Takano, Tomonori Harada, et al. · Journal of Nihon University Medical Association
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Works count: 38
Citation count: 466
H-index: 12
I10-index: 13
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