Get started
Author

José Augusto Ferreira Perez Villar

Observed names: J. A. F. P. Villar, J. Villar, J.A.F.P. Villar, Jose A. F. P. Villar, Jose Augusto F. Villar, Jose Augusto Ferreira Perez Villar, José Augusto Ferreira Perez Villar, José A. F. P. Villar, José A. P. F. Villar, José A.F.P. Villar, José Augusto F. P. Villar, José Augusto F.P. Villar, José Augusto FP Villar, José Augusto Ferreira Villar, José Augusto Villar, José Villar, Villar, J.A.F.P., Villar, José Augusto F. P.
ORCID: 0000-0003-1580-0644
Observed ORCID: 0000-0003-1580-0644
OpenAlex ID: A5056404162
Molecular modeling and inhibition of phospholipase A2 by polyhydroxy phenolic compounds
2008 · S.L. da Silva, A.K. Calgarotto, et al. · European Journal of Medicinal Chemistry · 61
Design, synthesis, biological activity and structure-activity relationship studies of chalcone derivatives as potential anti-Candida agents
2018 · Jéssica T. Andrade, Felipe R. S. Santos, et al. · The Journal of Antibiotics · 57
21-Benzylidene Digoxin: A Proapoptotic Cardenolide of Cancer Cells That Up-Regulates Na,K-ATPase and Epithelial Tight Junctions
2014 · Sayonarah C. Rocha, Marco T. C. Pessoa, et al. · PLoS ONE · 39
PDF
Design and Synthesis of New Chacones Substituted with Azide/Triazole Groups and Analysis of Their Cytotoxicity Towards HeLa Cells
2012 · Graziele D. Da Silva, Marina G. Da Silva, et al. · Molecules · 27
PDF
Selectivity analyses of γ-benzylidene digoxin derivatives to different Na,K-ATPase α isoforms: a molecular docking approach
2017 · Marco T. C. Pessôa, Silmara L. G. Alves, et al. · Journal of Enzyme Inhibition and Medicinal Chemistry · 24
PDF
Synthesis and Biological Evaluation of Novel 3-Alkylpyridine Marine Alkaloid Analogs with Promising Anticancer Activity
2014 · Alessandra Gonçalves, Aline De Lima, et al. · Marine Drugs · 24
PDF
Synthesis and evaluation of nitrostyrene derivative compounds, new snake venom phospholipase A2 inhibitors
2008 · J.A.F.P. Villar, F.T.D. Lima, et al. · Toxicon · 24
Differences of lipid membrane modulation and oxidative stress by digoxin and 21-benzylidene digoxin
2017 · Lilian N.D. Silva, Marco Tulio C. Pessoa, et al. · Experimental Cell Research · 23
21‑Benzylidene digoxin, a novel digoxin hemi-synthetic derivative, presents an anti-inflammatory activity through inhibition of edema, tumour necrosis factor alpha production, inducible nitric oxide synthase expression and leucocyte migration
2018 · Letícia Vieira, Aline Aparecida Saldanha, et al. · International Immunopharmacology · 21
PDF
21-Benzylidene digoxin decreases proliferation by inhibiting the EGFR/ERK signaling pathway and induces apoptosis in HeLa cells
2019 · Marco Túlio C. Pessôa, Jéssica M.M. Valadares, et al. · Steroids · 17
Evaluation of neuroprotective activity of digoxin and semisynthetic derivatives against partial chemical ischemia
2019 · Bruno de Souza Gonçalves, Jéssica M. de Moura Valadares, et al. · Journal of Cellular Biochemistry · 17
γ-Benzylidene digoxin derivatives synthesis and molecular modeling: Evaluation of anticancer and the Na,K-ATPase activity effect
2015 · Silmara L.G. Alves, Natasha Paixão, et al. · Bioorganic & Medicinal Chemistry · 17
Involvement of Src signaling in the synergistic effect between cisplatin and digoxin on cancer cell viability
2017 · Duane G. Pereira, Mariana A.R. Salgado, et al. · Journal of Cellular Biochemistry · 16
The Use of Reverse Vaccinology and Molecular Modeling Associated with Cell Proliferation Stimulation Approach to Select Promiscuous Epitopes from Schistosoma mansoni
2016 · Flávio M. Oliveira, Ivan E. V. Coelho, et al. · Applied Biochemistry and Biotechnology · 16
An easy and versatile approach to the synthesis of chiral pheromone lactones via 4,4-dimethyl-2-oxazoline derivatives
2004 · Paulo H.G. Zarbin, Alfredo R.M. Oliveira, et al. · Tetrahedron Letters · 16
Multifunctional modified carbon nanotubes as potential anti-tumor drug delivery
2023 · Pedro Gontijo Carneiro, Duane Gischewski Pereira, et al. · Surfaces and Interfaces · 12
Pharmacologic potential of new nitro-compounds as antimicrobial agents against nosocomial pathogens: design, synthesis, and in vitro effectiveness
2019 · Jéssica Tauany Andrade, Silmara Lucia Grego Alves, et al. · Folia Microbiologica · 12
Evaluation of Anti-Inflammatory Activity of the New Cardiotonic Steroid γ-Benzylidene Digoxin 8 (BD-8) in Mice
2024 · Davi Azevedo Ferreira, Anna Beatriz Araujo Medeiros, et al. · Cells · 11
PDF
Synthesis and in vitro evaluation of novel triazole/azide chalcones
2016 · Fernanda C. G. Evangelista, Maralice O. Bandeira, et al. · Medicinal Chemistry Research · 11
Molecular modeling of the inhibition of enzyme PLA2 from snake venom by dipyrone and 1‐phenyl‐3‐methyl‐5‐pyrazolone
2008 · S. L. Da Silva, M. Comar, et al. · International Journal of Quantum Chemistry · 11
Homogeneous CuCl2/TMEDA/TEMPO-Catalyzed chemoselective base- and halogen- free aerobic oxidation of primary alcohols in mild conditions
2021 · Emmanuel D. Silva, Otávio A.L. Alves, et al. · Applied Catalysis A General · 10
Synthesis of Pheromones: Highlights from 2002-2004
2009 · P. Zarbin, J. Villar, et al. · Current Organic Chemistry · 10
Insect pheromone synthesis in Brazil: an overview
2007 · Paulo H. G. Zarbin, José A. F. P. Villar, et al. · Journal of the Brazilian Chemical Society · 10
PDF
Implications of Synthetic Modifications of the Cardiotonic Steroid Lactone Ring on Cytotoxicity
2021 · Gisele Capanema de Oliveira, Sayonarah Carvalho Rocha, et al. · The Journal of Membrane Biology · 9
The γ-Benzylidene Digoxin Derivative BD-15 Increases the α3-Na, K-ATPase Activity in Rat Hippocampus and Prefrontal Cortex and no Change on Heart
2021 · Gabriela Machado Parreira, Jéssica Alves Faria, et al. · The Journal of Membrane Biology · 9
Works count: 63
Citation count: 584
H-index: 15
I10-index: 23
Year
Topic
Type