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Author

Guode Zhao

ORCID: 0000-0001-7649-5757
Observed ORCID: 0000-0001-7649-5757
OpenAlex ID: A5057467737
Tofacitinib Is a Mechanism-Based Inactivator of Cytochrome P450 3A4
2019 · Xiucai Guo, Wei Li, et al. · Chemical Research in Toxicology · 32
Studies on hepatotoxicity and toxicokinetics of colchicine
2019 · Xiucai Guo, Yan Chen, et al. · Journal of Biochemical and Molecular Toxicology · 25
2,3,5,4′-Tetrahydroxy stilbene-2-Ο-β-D-glucoside, a mechanism-based inactivator of CYP2C19 and CYP3A4, potentiates hepatic protein adduction and hepatotoxicity induced by emodin in vivo
2022 · Xu Wang, Lingwen Dong, et al. · Chemico-Biological Interactions · 15
The structure-based virtual screening of non-benzofuran inhibitors against M. tuberculosis Pks13-TE for anti-tuberculosis phenotypic discovery
2020 · Guode Zhao, Xirong Tian, et al. · New Journal of Chemistry · 15
Reduction of emodin-8-O-ß-D-glucoside content participates in processing-based detoxification of polygoni multiflori radix
2023 · Xu Wang, Guode Zhao, et al. · Phytomedicine · 13
Difference in hepatotoxicity of furan-containing components in cortex dictamni correlates the efficiency of their metabolic activation
2023 · Jie Pan, Chutian Wu, et al. · Phytomedicine · 12
Metabolic activation and hepatic cytotoxicity of osthole mediated by cytochrome P450 enzymes
2025 · Siyu Liu, Guode Zhao, et al. · Toxicology Letters · 11
Metabolic Activation of Pesticide Isoprocarb Mediated by CYP3A4 and the Possible Correlation with Its Cytotoxicity
2023 · Chunjing Guan, Guode Zhao, et al. · Journal of Agricultural and Food Chemistry · 10
Configurational Alteration Results in Change in Hepatotoxicity of Asarone
2022 · Guode Zhao, Yufei Ma, et al. · Journal of Agricultural and Food Chemistry · 9
Hepatic RNA adduction derived from metabolic activation of retrorsine in vitro and in vivo
2022 · Weiwei Li, Ting Cheng, et al. · Chemico-Biological Interactions · 9
Enhancing Aromaticity of Alkenylbenzenes May Decrease Their Metabolic Activation and Reduce Their Potential Cytotoxicity: Lessons Learnt from the Investigation of Myristicin and Elemicin
2024 · Guode Zhao, Zixia Hu, et al. · Journal of Medicinal Chemistry · 7
Mechanistic Understanding of Differences in Cytotoxicity Induced by Food Additives Methyleugenol and Methylisoeugenol
2025 · Guode Zhao, Jiannan Zheng, et al. · Journal of Agricultural and Food Chemistry · 6
Metabolic Activation and Cytotoxicity of Gramine Mediated by CYP3A in Rats
2024 · Xingyu Gao, Zixia Hu, et al. · Journal of Agricultural and Food Chemistry · 6
Metabolic Activation and Cytotoxicity of Donepezil Induced by CYP3A4
2024 · Jiannan Zheng, Jiannan Zheng, et al. · Chemical Research in Toxicology · 5
Chelerythrine Chloride is an Affinity-Labeling Inactivator of CYP3A4 by Modification of Cysteine239
2024 · Xu Mao, Guode Zhao, et al. · Journal of Medicinal Chemistry · 5
In Vitro and In Vivo Metabolic Activation of Tolterodine Mediated by CYP3A
2023 · Aixuan Wang, Qiang Zhao, et al. · Chemical Research in Toxicology · 5
Correlation of Vanillin-Induced Cytotoxicity with CYP3A-Mediated Metabolic Activation
2024 · Qiang Zhao, Zixia Hu, et al. · Journal of Agricultural and Food Chemistry · 4
Mass Spectrometry Imaging of Amino Acids Enabled by Quaternized Pyridinium Salt MALDI Probe
2024 · Hao Zhou, Jie Yuan, et al. · Analytical Chemistry · 4
Mechanism-Based Inactivation of CYP2D6 by Phellopterin and Related Drug–Drug Interaction with Metoprolol
2024 · Zihao Cheng, Yan He, et al. · Journal of Agricultural and Food Chemistry · 4
Glutathione conjugation and protein modification resulting from metabolic activation of pesticide metalaxyl in vitro and in vivo
2023 · Yang Wang, Aixuan Wang, et al. · Pesticide Biochemistry and Physiology · 4
Metabolic Activation of Perampanel Mediated by CYP1A2
2022 · Zifang Ding, Xu Wang, et al. · Chemical Research in Toxicology · 4
RNA Adduction Resulting from the Metabolic Activation of Myristicin by P450 Enzymes and Sulfotransferases
2024 · Yan He, Zihao Cheng, et al. · Journal of Agricultural and Food Chemistry · 3
Histones H2B/H3 Selectively Modified by a cis-Enedial Metabolite Resulting from the Metabolic Action of Diosbulbin B: Potential Target Proteins for the Antitumor Agent Design
2025 · Yi Yang, Weiwei Li, et al. · Journal of Medicinal Chemistry · 2
Metabolic Activation of trans-Anethole Plays a Role in Hepatic Cytotoxicity in Mice
2025 · Yan Shen, Yang Wang, et al. · Journal of Agricultural and Food Chemistry · 2
Metabolic Activation of Stiripentol Correlates with Cytotoxicity
2025 · Ziying Jiang, Yang Wang, et al. · Chemical Research in Toxicology · 2
Works count: 28
Citation count: 216
H-index: 9
I10-index: 8
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