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Kim G.M. Savelkouls

Observed names: K. G. M. Savelkouls, Kim G. M. Savelkouls, Kim G. Savelkouls, Kim Savelkouls, Savelkouls, Kim G. M., Savelkouls, Kim G.M.
OpenAlex ID: A5057634848
The unfolded protein response protects human tumor cells during hypoxia through regulation of the autophagy genes MAP1LC3B and ATG5
2009 · Kasper M.A. Rouschop, Twan van den Beucken, et al. · Journal of Clinical Investigation · 826
Gene expression during acute and prolonged hypoxia is regulated by distinct mechanisms of translational control
2006 · Marianne Koritzinsky, Michaël G Magagnin, et al. · The EMBO Journal · 363
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Autophagy is required during cycling hypoxia to lower production of reactive oxygen species
2009 · Kasper M.A. Rouschop, Chantal H.M.A. Ramaekers, et al. · Radiotherapy and Oncology · 142
Hypoxia-induced Expression of Carbonic Anhydrase 9 Is Dependent on the Unfolded Protein Response
2009 · Twan van den Beucken, Marianne Koritzinsky, et al. · Journal of Biological Chemistry · 71
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Immunoregulatory gene polymorphisms are associated with ANCA-related vasculitis
2008 · Marjan C. Slot, Milena G. Sokolowska, et al. · Clinical Immunology · 67
Phosphorylation of eIF2α is required for mRNA translation inhibition and survival during moderate hypoxia
2007 · Marianne Koritzinsky, Kasper M.A. Rouschop, et al. · Radiotherapy and Oncology · 55
EGFR overexpressing cells and tumors are dependent on autophagy for growth and survival
2013 · Barry Jutten, Tom G. Keulers, et al. · Radiotherapy and Oncology · 52
The rat cytomegalovirus R78 G protein-coupled receptor gene is required for production of infectious virus in the spleen
2003 · Suzanne J. F. Kaptein, Patrick S. Beisser, et al. · Journal of General Virology · 47
EGFRvIII expression triggers a metabolic dependency and therapeutic vulnerability sensitive to autophagy inhibition
2018 · Barry Jutten, Tom G. Keulers, et al. · Autophagy · 46
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The autophagy associated gene, ULK1, promotes tolerance to chronic and acute hypoxia
2013 · Marco B.E. Schaaf, Dan Cojocari, et al. · Radiotherapy and Oncology · 46
Secretion of pro‐angiogenic extracellular vesicles during hypoxia is dependent on the autophagy‐related protein GABARAPL1
2021 · Tom G. Keulers, Sten F. Libregts, et al. · Journal of Extracellular Vesicles · 38
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ATG12 deficiency results in intracellular glutamine depletion, abrogation of tumor hypoxia and a favorable prognosis in cancer
2021 · Tom G. Keulers, Alexander Koch, et al. · Autophagy · 30
Regulation of Cited2 expression provides a functional link between translational and transcriptional responses during hypoxia
2007 · Twan van den Beucken, Michael G. Magagnin, et al. · Radiotherapy and Oncology · 29
Targeting serine/glycine metabolism improves radiotherapy response in non-small cell lung cancer
2023 · Anaís Sánchez-Castillo, Elien Heylen, et al. · British Journal of Cancer · 26
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GABARAPL1 is required for increased EGFR membrane expression during hypoxia
2015 · Tom G. Keulers, Marco B.E. Schaaf, et al. · Radiotherapy and Oncology · 26
Canonical autophagy does not contribute to cellular radioresistance
2015 · Marco B.E. Schaaf, Barry Jutten, et al. · Radiotherapy and Oncology · 26
Deregulation of cap-dependent mRNA translation increases tumour radiosensitivity through reduction of the hypoxic fraction
2011 · Kasper M.A. Rouschop, Ludwig Dubois, et al. · Radiotherapy and Oncology · 23
Sertraline/chloroquine combination therapy to target hypoxic and immunosuppressive serine/glycine synthesis-dependent glioblastomas
2024 · Anaís Sánchez-Castillo, Kim G. Savelkouls, et al. · Oncogenesis · 11
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Cancer EV stimulate endothelial glycolysis to fuel protein synthesis via mTOR and AMPKα activation
2024 · Joël E. J. Beaumont, Lydie M. O. Barbeau, et al. · Journal of Extracellular Vesicles · 7
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GABARAPL1 is essential in extracellular vesicle cargo loading and metastasis development
2023 · Joel E.J. Beaumont, Jinzhe Ju, et al. · Radiotherapy and Oncology · 7
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Identification and characterization of two antisense transcripts from the major immediate early region of rat cytomegalovirus
2005 · K. W. R. van Cleef, M. J. Blok, et al. · Archives of Virology · 6
MAP1LC3C repression reduces CIITA- and HLA class II expression in non-small cell lung cancer
2025 · Lydie M. O. Barbeau, Nicky A. Beelen, et al. · PLoS ONE · 3
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Normoxic HIFα-mediated metabolic rewiring in cancer as a novel therapeutic target of tumor heterogeneity
2026 · Anaís Sánchez-Castillo, Jairo G. E. Lommen, et al. · Cancer & Metabolism · 1
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1866: Targeting serine/glycine metabolism improves radiotherapy response in Non-Small Cell Lung Cancer
2024 · Anaís Sánchez Castillo, Elien Heylen, et al. · Radiotherapy and Oncology
Correction: Targeting serine/glycine metabolism improves radiotherapy response in non-small cell lung cancer
2024 · Anaís Sánchez-Castillo, Elien Heylen, et al. · British Journal of Cancer
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Works count: 30
Citation count: 1,948
H-index: 17
I10-index: 18
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