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Henri Bénech

Observed names: Benech, H., Benech, Henri, H Benech, H. BENECH, H. Benech, H. Bénech, Henri Benech, Henri Bénech, Henri C Benech
Observed institutions: Hôpital Necker-Enfants Malades, Inserm, Institut Pasteur, Commissariat à l'Énergie Atomique et aux Énergies Alternatives, Université Paris-Saclay, CEA Paris-Saclay - Etablissement de Saclay, Institut Necker Enfants Malades, Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement, CEA Paris-Saclay - Etablissement de Fontenay-aux-roses, Assistance Publique – Hôpitaux de Paris, CEA Cadarache, Pitié-Salpêtrière Hospital, CEA Paris-Saclay, Institut de Biologie et Technologies, Institut du Cerveau, Bicêtre Hospital, Hôpital Saint-Vincent-de-Paul, Direction des Sciences du Vivant, Médicaments et Technologies pour la Santé
ORCID: 0000-0003-3181-3744
Observed ORCID: 0000-0003-3181-3744
OpenAlex ID: A5057863442
Measurement of Intracellular Didanosine and Tenofovir Phosphorylated Metabolites and Possible Interaction of the Two Drugs in Human Immunodeficiency Virus-Infected Patients
2005 · Alain Pruvost, Eugènia Negredo, et al. · Antimicrobial Agents and Chemotherapy · 113
Transmembrane diffusion of gemcitabine by a nanoparticulate squalenoyl prodrug: An original drug delivery pathway
2010 · L. Bildstein, C. Dubernet, et al. · Journal of Controlled Release · 105
Improved method for the simultaneous determination of d4T, 3TC and ddl intracellular phosphorylated anabolites in human peripheral‐blood mononuclear cells using high‐performance liquid chromatography/tandem mass spectrometry
2002 · François Becher, Alain Pruvost, et al. · Rapid Communications in Mass Spectrometry · 97
Atp Binding Cassette Multidrug Transporters Limit the Anti-HIV Activity of Zidovudine and Indinavir in Infected Human Macrophages
2004 · Sylvie Jorajuria, Nathalie Dereuddre-Bosquet, et al. · Antiviral Therapy · 87
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Direct lung delivery of a dry powder formulation of DTPA with improved aerosolization properties: Effect on lung and systemic decorporation of plutonium
2006 · C. Gervelas, A.-L. Serandour, et al. · Journal of Controlled Release · 80
Monitoring of didanosine and stavudine intracellular trisphosphorylated anabolite concentrations in HIV-infected patients
2004 · François Becher, Roland Landman, et al. · AIDS · 72
Direct determination of phosphorylated intracellular anabolites of stavudine (d4T) by liquid chromatography/tandem mass spectrometry
2001 · Alain Pruvost, François Becher, et al. · Rapid Communications in Mass Spectrometry · 72
A cocktail of metabolic probes demonstrates the relevance of primary human hepatocyte cultures in a microfluidic biochip for pharmaceutical drug screening
2011 · Jean-Matthieu Prot, Orianne Videau, et al. · International Journal of Pharmaceutics · 71
In VitroPrimary Human and Animal Cell-Based Blood−Brain Barrier Models as a Screening Tool in Drug Discovery
2011 · Olivier Lacombe, Orianne Videau, et al. · Molecular Pharmaceutics · 70
Effect of a short-term HAART on SIV load in macaque tissues is dependent on time of initiation and antiviral diffusion
2010 · Olivier Bourry, Abdelkrim Mannioui, et al. · Retrovirology · 67
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Liquid chromatography–tandem mass spectrometry assays for intracellular deoxyribonucleotide triphosphate competitors of nucleoside antiretrovirals
2003 · Gaëlle Henneré, François Becher, et al. · Journal of Chromatography B · 59
Pharmacokinetics of DTPA entrapped in conventional and long-circulating liposomes of different size for plutonium decorporation
2005 · Guillaume Phan, Amaury Herbet, et al. · Journal of Controlled Release · 58
A strategy for liquid chromatography/tandem mass spectrometric assays of intracellular drugs: application to the validation of the triphosphorylated anabolite of antiretrovirals in peripheral blood mononuclear cells
2003 · François Becher, Alain Pruvost, et al. · Journal of Mass Spectrometry · 58
Evidence and Possible Consequences of the Phosphorylation of Nucleoside Reverse Transcriptase Inhibitors in Human Red Blood Cells
2007 · Lucie Durand-Gasselin, David Da Silva, et al. · Antimicrobial Agents and Chemotherapy · 56
Specificity enhancement with LC‐positive ESI‐MS/MS for the measurement of nucleotides: application to the quantitative determination of carbovir triphosphate, lamivudine triphosphate and tenofovir diphosphate in human peripheral blood mononuclear cells
2007 · Alain Pruvost, Frédéric Théodoro, et al. · Journal of Mass Spectrometry · 53
P-Glycoprotein, Breast Cancer Resistance Protein, Organic Anion Transporter 3, and Transporting Peptide 1a4 during Blood–Brain Barrier Maturation: Involvement of Wnt/β-Catenin and Endothelin-1 Signaling
2012 · Rania Harati, Henri Benech, et al. · Molecular Pharmaceutics · 50
Evaluation of seven drug metabolisms and clearances by cryopreserved human primary hepatocytes cultivated in microfluidic biochips
2012 · Régis Baudoin, Jean Matthieu Prot, et al. · Xenobiotica · 47
Development of a Direct Assay for Measuring Intracellular AZT Triphosphate in Humans Peripheral Blood Mononuclear Cells
2002 · François Becher, Dimitri Schlemmer, et al. · Analytical Chemistry · 47
Development and validation of a liquid chromatographic/tandem mass spectrometric assay for the quantitation of nucleoside HIV reverse transcriptase inhibitors in biological matrices
2005 · Séverine Compain, Dimitri Schlemmer, et al. · Journal of Mass Spectrometry · 42
Peripheral blood mononuclear cell counting using a DNA-detection-based method
2004 · Henri Benech, Frédéric Théodoro, et al. · Analytical Biochemistry · 40
Significant levels of intracellular stavudine triphosphate are found in HIV-infected zidovudine-treated patients
2003 · François Becher, Alain G Pruvost, et al. · AIDS · 39
Prevention of vaginal simian immunodeficiency virus transmission in macaques by postexposure prophylaxis with zidovudine, lamivudine and indinavir
2009 · Olivier Bourry, Patricia Brochard, et al. · AIDS · 34
Development and validation of an LC/MS/MS assay for mycophenolic acid in human peripheral blood mononuclear cells
2007 · Henri Bénech, Sophie Hascoët, et al. · Journal of Chromatography B · 32
Biochemical and analytical development of the CIME cocktail for drug fate assessment in humans
2010 · Orianne Videau, Marcel Delaforge, et al. · Rapid Communications in Mass Spectrometry · 30
High Levels of Zidovudine (AZT) and Its Intracellular Phosphate Metabolites in AZT- and AZT-Lamivudine-Treated Newborns of Human Immunodeficiency Virus-Infected Mothers
2008 · Lucie Durand-Gasselin, Alain Pruvost, et al. · Antimicrobial Agents and Chemotherapy · 30
Works count: 89
Citation count: 2,134
H-index: 29
I10-index: 52
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