Author

Sylvia Varland

Observed name: Varland, Sylvia

Institutions: University of Toronto, University of Bergen

Observed institutions: University of Toronto, Haukeland University Hospital, University of Bergen

ORCID: 0000-0002-7303-2391

Observed ORCID: 0000-0002-7303-2391

OpenAlex ID: A5058297242

Spotlight on protein N-terminal acetylation

2018 · Rasmus Ree, Sylvia Varland, et al. · Experimental & Molecular Medicine · 646

PDF

N‐terminal modifications of cellular proteins: The enzymes involved, their substrate specificities and biological effects

2015 · Sylvia Varland, Camilla Osberg, et al. · PROTEOMICS · 211

PDF

NAA80 is actin’s N-terminal acetyltransferase and regulates cytoskeleton assembly and cell motility

2018 · Adrian Drazic, Henriette Aksnes, et al. · Proceedings of the National Academy of Sciences · 192

PDF

Actin Post-translational Modifications: The Cinderella of Cytoskeletal Control

2019 · Sylvia Varland, Joël Vandekerckhove, et al. · Trends in Biochemical Sciences · 149

PDF

N-terminal acetylation shields proteins from degradation and promotes age-dependent motility and longevity

2023 · Sylvia Varland, Rui Duarte Silva, et al. · Nature Communications · 81

PDF

Truncating Variants in NAA15 Are Associated with Variable Levels of Intellectual Disability, Autism Spectrum Disorder, and Congenital Anomalies

2018 · Hanyin Cheng, Avinash V. Dharmadhikari, et al. · The American Journal of Human Genetics · 80

PDF

Structural determinants and cellular environment define processed actin as the sole substrate of the N-terminal acetyltransferase NAA80

2018 · Marianne Goris, Robert S. Magin, et al. · Proceedings of the National Academy of Sciences · 69

Mechanisms of Congenital Heart Disease Caused by NAA15 Haploinsufficiency

2021 · Tarsha Ward, Warren Tai, et al. · Circulation Research · 45

PDF

PFN2 and NAA80 cooperate to efficiently acetylate the N-terminus of actin

2020 · Rasmus Ree, Laura Kind, et al. · Journal of Biological Chemistry · 33

N-terminal Acetylation Levels Are Maintained During Acetyl-CoA Deficiency in Saccharomyces cerevisiae

2018 · Sylvia Varland, Henriette Aksnes, et al. · Molecular & Cellular Proteomics · 28

PDF

The Final Maturation State of β-actin Involves N-terminal Acetylation by NAA80, not N-terminal Arginylation by ATE1

2021 · Adrian Drazic, Evy Timmerman, et al. · Journal of Molecular Biology · 18

PDF

Identification of an alternatively spliced nuclear isoform of human N-terminal acetyltransferase Naa30

2017 · Sylvia Varland, Line M. Myklebust, et al. · Gene · 16

Investigating the functionality of a ribosome-binding mutant of NAA15 using Saccharomyces cerevisiae

2018 · Sylvia Varland, Thomas Arnesen · BMC Research Notes · 11

PDF

A nonsense variant in the N‐terminal acetyltransferase NAA30 may be associated with global developmental delay and tracheal cleft

2023 · Sylvia Varland, Kirsten Marie Brønstad, et al. · American Journal of Medical Genetics Part A · 7

PDF

Human NAA30 can rescue yeast mak3∆ mutant growth phenotypes

2021 · Adrian Drazic, Sylvia Varland · Bioscience Reports · 7

Global genetic interaction network of a human cell maps conserved principles and informs functional interpretation of gene co-essentiality profiles

2026 · Maximilian Billmann, Michael Costanzo, et al. · Cell · 5

A global genetic interaction map of a human cell reveals conserved principles of genetic networks

2025 · Maximilian Billmann, Michael Costanzo, et al. · bioRxiv (Cold Spring Harbor Laboratory) · 5

A global genetic interaction network of a human cell maps conserved principles and informs functional interpretation of gene co-essentiality profiles. Billmann et al.

2026 · Billmann, Maximilian, Costanzo, Michael, et al. · Mendeley Data

Metabolic regulation of N-terminal acetylation in Saccharomyces cerevisiae

2015 · Sylvia Varland, Petra Van Damme, et al. · Ghent University Academic Bibliography (Ghent University)

Works count: 19

Citation count: 1,603

H-index: 12

I10-index: 13