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Yichen Xiang
Institutions:
Broad Institute,
Koch Institute for Integrative Cancer Research At MIT,
Massachusetts Institute of Technology
Observed institutions:
Broad Institute,
University of California San Diego,
Koch Institute for Integrative Cancer Research At MIT,
Massachusetts Institute of Technology
ORCID:
0009-0001-3937-8073
Observed ORCID:
0009-0001-3937-8073
OpenAlex ID:
A5058531718
Efficient in vitro and in vivo RNA editing via recruitment of endogenous ADARs using circular guide RNAs
2022
·
Dhruva Katrekar
, James Yen
, et al.
·
Nature Biotechnology
·
189
PDF
Comprehensive interrogation of the ADAR2 deaminase domain for engineering enhanced RNA editing activity and specificity
2022
·
Dhruva Katrekar
, Nathan Palmer
, et al.
·
eLife
·
51
Robust genome and cell engineering via in vitro and in situ circularized RNAs
2024
·
Michael Tong
, Nathan Palmer
, et al.
·
Nature Biomedical Engineering
·
31
PDF
Targeted degradation of CDK9 potently disrupts the MYC-regulated network
2025
·
Mohammed A. Toure
, Keisuke Motoyama
, et al.
·
Cell chemical biology
·
22
Methods for recruiting endogenous and exogenous ADAR enzymes for site-specific RNA editing
2022
·
Yichen Xiang
, Dhruva Katrekar
, et al.
·
Methods
·
10
A functional map of CDK-drug interactions at single amino acid resolution
2025
·
Samuel I. Gould
, Jonuelle Acosta
, et al.
·
bioRxiv (Cold Spring Harbor Laboratory)
·
1
Small molecule modulators of TOX protein re-invigorate T cell activity
2025
·
Bocheng Wu
, Heng Jui Chang
, et al.
·
bioRxiv (Cold Spring Harbor Laboratory)
·
1
Extensive in vitro and in vivo protein translation via in situ circularized RNAs
2022
·
Aditya Kumar
, Nathan Palmer
, et al.
·
bioRxiv (Cold Spring Harbor Laboratory)
·
1
PDF
Generalizable Strategies for the Synthesis of Cereblon‐Recruiting PROTAC Prodrugs
2026
·
Aiden X. Wang
, Bin Liu
, et al.
·
Angewandte Chemie
Generalizable Strategies for the Synthesis of Cereblon‐Recruiting PROTAC Prodrugs
2026
·
Aiden X. Wang
, Bin Liu
, et al.
·
Angewandte Chemie International Edition
PDF
Epigenetic Reactivation of Lineage Differentiation to Target Leukemia
2026
·
Shandon M. Amos
, Chi-Chao Chen
, et al.
·
bioRxiv (Cold Spring Harbor Laboratory)
Abstract 5156: Development of FBXW7 binders for targeted protein degradation
2026
·
Shenghao Guo
, Becky Leifer
, et al.
·
Cancer Research
Abstract 2418: Non-covalent small molecule probe discovery of large intrinsically disordered protein
2026
·
Yichen Xiang
, Marc Ramos Sala
, et al.
·
Cancer Research
Abstract 7020: Chemical probe discovery for PAX3::FOXO1 via small-molecule microarrays
2025
·
Yichen Xiang
, Marc Ramos Sala
, et al.
·
Cancer Research
Author response: Comprehensive interrogation of the ADAR2 deaminase domain for engineering enhanced RNA editing activity and specificity
2022
·
Dhruva Katrekar
, Yichen Xiang
, et al.
·
eLife
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Works count:
15
Citation count:
306
H-index:
5
I10-index:
5
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