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Philip McGoldrick
Observed names:
McGoldrick, P,
McGoldrick, Philip,
P. McGoldrick,
Philip Mcgoldrick,
Phillip McGoldrick
Institution:
University of Toronto
Observed institutions:
Tongji University,
Sunnybrook Health Science Centre,
Mayo Clinic,
University of Toronto,
Mayo Clinic in Florida,
National Hospital for Neurology and Neurosurgery,
UCL Queen Square Institute of Neurology,
University College London
show all 8
ORCID:
0000-0003-1804-9876
Observed ORCID:
0000-0003-1804-9876
OpenAlex ID:
A5058720562
Overexpression of human wild-type FUS causes progressive motor neuron degeneration in an age- and dose-dependent fashion
2012
·
Jacqueline C. Mitchell
, Philip McGoldrick
, et al.
·
Acta Neuropathologica
·
289
PDF
Rodent models of amyotrophic lateral sclerosis
2013
·
Philip McGoldrick
, Peter I. Joyce
, et al.
·
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
·
156
PDF
Isoform‐specific antibodies reveal distinct subcellular localizations of C 9orf72 in amyotrophic lateral sclerosis
2015
·
Shangxi Xiao
, Laura MacNair
, et al.
·
Annals of Neurology
·
138
PDF
The C9orf72 repeat expansion itself is methylated in ALS and FTLD patients
2015
·
Zhengrui Xi
, Ming Zhang
, et al.
·
Acta Neuropathologica
·
136
PDF
Pathogenic Parkinson’s disease mutations across the functional domains of LRRK2 alter the autophagic/lysosomal response to starvation
2013
·
Claudia Manzoni
, Adamantios Mamais
, et al.
·
Biochemical and Biophysical Research Communications
·
81
A novel SOD1-ALS mutation separates central and peripheral effects of mutant SOD1 toxicity
2014
·
Peter I. Joyce
, Philip Mcgoldrick
, et al.
·
Human Molecular Genetics
·
62
PDF
DNA methylation age acceleration is associated with ALS age of onset and survival
2020
·
Ming Zhang
, Paul M. McKeever
, et al.
·
Acta Neuropathologica
·
55
PDF
Jump from Pre-mutation to Pathologic Expansion in C9orf72
2015
·
Zhengrui Xi
, Marka van Blitterswijk
, et al.
·
The American Journal of Human Genetics
·
53
PDF
A C6orf10/LOC101929163 locus is associated with age of onset in C9orf72 carriers
2018
·
Ming Zhang
, Raffaele Ferrari
, et al.
·
Brain
·
50
PDF
The FUS gene is dual-coding with both proteins contributing to FUS-mediated toxicity
2020
·
Marie A Brunet
, Jean-Francois Jacques
, et al.
·
EMBO Reports
·
47
PDF
Unaffected mosaic C9orf72 case
2017
·
Philip McGoldrick
, Ming Zhang
, et al.
·
Neurology
·
46
PDF
C9orf72 isoforms in Amyotrophic Lateral Sclerosis and Frontotemporal Lobar Degeneration
2016
·
Shangxi Xiao
, Laura MacNair
, et al.
·
Brain Research
·
44
Neuropathologic description of CHCHD10 mutated amyotrophic lateral sclerosis
2020
·
Julia L. Keith
, Emily Swinkin
, et al.
·
Neurology Genetics
·
32
PDF
Novel mutations in human and mouse SCN4A implicate AMPK in myotonia and periodic paralysis
2014
·
Silvia Corrochano
, Roope Männikkö
, et al.
·
Brain
·
29
PDF
Pathogenic LRRK2 Mutations Do Not Alter Gene Expression in Cell Model Systems or Human Brain Tissue
2011
·
Michael J. Devine
, Alice Kaganovich
, et al.
·
PLoS ONE
·
28
PDF
Loss of C9orf72 perturbs the Ran-GTPase gradient and nucleocytoplasmic transport, generating compositionally diverse Importin β-1 granules
2023
·
Philip McGoldrick
, Agnes Lau
, et al.
·
Cell Reports
·
27
Unraveling the impact of disrupted nucleocytoplasmic transport systems in C9orf72-associated ALS
2023
·
Philip McGoldrick
, Janice Robertson
·
Frontiers in Cellular Neuroscience
·
21
PDF
Deficiency of the zinc finger protein ZFP106 causes motor and sensory neurodegeneration
2015
·
Peter I. Joyce
, Pietro Fratta
, et al.
·
Human Molecular Genetics
·
21
PDF
Single-nucleus transcriptome atlas of orbitofrontal cortex in ALS with a deep learning-based decoding of alternative polyadenylation mechanisms
2025
·
Paul M. McKeever
, Aiden M. Sababi
, et al.
·
Cell Genomics
·
19
A Nonsense Mutation in Mouse Tardbp Affects TDP43 Alternative Splicing Activity and Causes Limb-Clasping and Body Tone Defects
2014
·
Thomas Ricketts
, Philip McGoldrick
, et al.
·
PLoS ONE
·
18
PDF
C9orf72 repeat expansion creates the unstable folate-sensitive fragile site FRA9A
2024
·
Mila Mirceta
, Monika H M Schmidt
, et al.
·
NAR Molecular Medicine
·
13
C9orf72 deficiency impairs the autophagic response to aggregated TDP-25 and exacerbates TDP-25-mediated neurodegeneration in vivo
2025
·
Lilian Tsai-Wei Lin
, Marc Shenouda
, et al.
·
Acta Neuropathologica Communications
·
8
PDF
C9orf72 expansion creates the unstable folate-sensitive fragile site FRA9A
2024
·
Mila Mirceta
, Monika H.M. Schmidt
, et al.
·
bioRxiv (Cold Spring Harbor Laboratory)
·
1
FUS gene is dual-coding with both proteins united in FUS-mediated toxicity
2019
·
Marie A. Brunet
, Jean-Francois Jacques
, et al.
·
bioRxiv (Cold Spring Harbor Laboratory)
·
1
PDF
O18 A new mouse model of ALS carrying a point mutation in the mouse Sod1 gene
2011
·
P. Joyce
, P. Fratta
, et al.
·
Neuromuscular Disorders
·
1
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Works count:
41
Citation count:
1,375
H-index:
19
I10-index:
21
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