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Carlos Moreno–Yruela
Observed names:
C. Moreno-Yruela,
Carlos Moreno-Yruela,
Moreno-Yruela, Carlos
Institution:
United Arab Emirates University
Observed institutions:
University of Copenhagen,
Harvard University,
United Arab Emirates University,
Universidad de Zaragoza,
Massachusetts General Hospital,
Instituto de Nanociencia y Materiales de Aragón,
École Polytechnique Fédérale de Lausanne
show all 7
ORCID:
0000-0003-2450-6519
Observed ORCID:
0000-0003-2450-6519
OpenAlex ID:
A5059071312
Works
31
Awards
2
Class I histone deacetylases (HDAC1–3) are histone lysine delactylases
2022
·
Carlos Moreno-Yruela
, Di Zhang
, et al.
·
Science Advances
·
930
Lysine l-lactylation is the dominant lactylation isomer induced by glycolysis
2024
·
Di Zhang
, Jinjun Gao
, et al.
·
Nature Chemical Biology
·
221
Histone Deacetylase 11 Is an ε-N-Myristoyllysine Hydrolase
2018
·
Carlos Moreno-Yruela
, Iacopo Galleano
, et al.
·
Cell chemical biology
·
150
PDF
Chiral Posttranslational Modification to Lysine ε-Amino Groups
2022
·
Carlos Moreno-Yruela
, Michael Bæk
, et al.
·
Accounts of Chemical Research
·
90
PDF
D−π–A Compounds with Tunable Intramolecular Charge Transfer Achieved by Incorporation of Butenolide Nitriles as Acceptor Moieties
2015
·
Carlos Moreno-Yruela
, Javier Garín
, et al.
·
The Journal of Organic Chemistry
·
60
Mechanism-based inhibitors of SIRT2: structure–activity relationship, X-ray structures, target engagement, regulation of α-tubulin acetylation and inhibition of breast cancer cell migration
2021
·
Alexander L. Nielsen
, Nima Rajabi
, et al.
·
RSC Chemical Biology
·
54
PDF
Determination of Slow-Binding HDAC Inhibitor Potency and Subclass Selectivity
2022
·
Carlos Moreno-Yruela
, Christian A. Olsen
·
ACS Medicinal Chemistry Letters
·
44
PDF
Zn2+-Dependent Histone Deacetylases in Plants: Structure and Evolution
2021
·
Inmaculada Yruela
, Carlos Moreno-Yruela
, et al.
·
Trends in Plant Science
·
40
PDF
Hydroxamic acid-modified peptide microarrays for profiling isozyme-selective interactions and inhibition of histone deacetylases
2021
·
Carlos Moreno-Yruela
, Michael Bæk
, et al.
·
Nature Communications
·
36
PDF
Kinetic Tuning of HDAC Inhibitors Affords Potent Inducers of Progranulin Expression
2019
·
Carlos Moreno-Yruela
, Daniel M. Fass
, et al.
·
ACS Chemical Neuroscience
·
26
Structural basis of SIRT7 nucleosome engagement and substrate specificity
2025
·
Carlos Moreno-Yruela
, Babatunde E. Ekundayo
, et al.
·
Nature Communications
·
22
PDF
Slow-Binding and Covalent HDAC Inhibition: A New Paradigm?
2024
·
Yasir S. Raouf
, Carlos Moreno-Yruela
·
JACS Au
·
20
PDF
High-throughput screening of histone deacetylases and determination of kinetic parameters using fluorogenic assays
2021
·
Carlos Moreno-Yruela
, Christian A. Olsen
·
STAR Protocols
·
15
PDF
Discovery of De Novo Macrocycle Inhibitors of Histone Deacetylase 11
2025
·
Daniela Danková
, Alexander L. Nielsen
, et al.
·
JACS Au
·
14
Synthesis of Trifluoromethyl Ketone Containing Amino Acid Building Blocks for the Preparation of Peptide-Based Histone Deacetylase (HDAC) Inhibitors
2018
·
Christian Olsen
, Carlos Moreno-Yruela
·
Synthesis
·
13
V-shaped pyranylidene/triphenylamine-based chromophores with enhanced photophysical, electrochemical and nonlinear optical properties
2021
·
Sergio Gámez-Valenzuela
, David Neusser
, et al.
·
Materials Advances
·
11
Distribution and diversity of classical deacylases in bacteria
2024
·
Leonie G. Graf
, Carlos Moreno-Yruela
, et al.
·
Nature Communications
·
7
PDF
Kinetic characterization of inhibitors of histone deacetylases (HDACs) and sirtuins
2019
·
Carlos Moreno-Yruela
, Andreas Stahl Madsen
, et al.
·
Research Square
·
7
PDF
Revealing chromatin-specific functions of histone deacylases
2024
·
Carlos Moreno-Yruela
, Beat Fierz
·
Biochemical Society Transactions
·
4
Building Blocks for the Screening of Histone Deacetylase Inhibitors Using μSPOT
2025
·
Carlos Moreno-Yruela
, Vita Sereikaite
·
Methods in molecular biology
·
1
A Fluorescent Nucleosome Platform for High-Throughput Sirtuin Kinetic Analysis and Inhibitor Discovery
2026
·
Carlos Moreno-Yruela
, Esther Calvino-Sanles
, et al.
·
ChemRxiv
PDF
MagIC beads for scarce macromolecules
2025
·
Carlos Moreno-Yruela
, Beat Fierz
·
eLife
PDF
Author response for "Mechanism-based inhibitors of SIRT2: structure-activity relationship, X-ray structures, target engagement, regulation of alpha-tubulin acetylation and inhibition of breast cancer cell migration"
2020
·
Nielsen, Alexander L.
, Rajabi, Nima
, et al.
·
Publons reviews and discussion
Hydroxamic Acid-Containing Peptides in the Study of Histone Deacetylases
2019
·
Carlos Moreno-Yruela
, Christian A. Olsen
·
Topics in medicinal chemistry
Elucidating the Enzymatic Activity of HDAC11
2018
·
Moreno-Yruela, Carlos
, Galleano, Iacopo
, et al.
·
Research at the University of Copenhagen (University of Copenhagen)
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Works count:
31
Citation count:
1,765
H-index:
14
I10-index:
16
Year
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