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Lotte Bruens

Plasticity of Lgr5-Negative Cancer Cells Drives Metastasis in Colorectal Cancer
2020 · Arianna Fumagalli, Koen C. Oost, et al. · Cell stem cell · 321
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How successful are AI-discovered drugs in clinical trials? A first analysis and emerging lessons
2024 · Madura KP Jayatunga, Margaret Ayers, et al. · Drug Discovery Today · 164
Wnt ligands influence tumour initiation by controlling the number of intestinal stem cells
2018 · D. J. Huels, L. Bruens, et al. · Nature Communications · 100
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In Vivo Imaging Reveals Existence of Crypt Fission and Fusion in Adult Mouse Intestine
2017 · Lotte Bruens, Saskia I.J. Ellenbroek, et al. · Gastroenterology · 80
Retrograde movements determine effective stem cell numbers in the intestine
2022 · Maria Azkanaz, Bernat Corominas-Murtra, et al. · Nature · 66
Calorie Restriction Increases the Number of Competing Stem Cells and Decreases Mutation Retention in the Intestine
2020 · Lotte Bruens, Saskia Inge Johanna Ellenbroek, et al. · Cell Reports · 56
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Mother cells control daughter cell proliferation in intestinal organoids to minimize proliferation fluctuations
2022 · Guizela Huelsz-Prince, Rutger N.U. Kok, et al. · eLife · 22
Capturing Stem Cell Behavior Using Intravital and Live Cell Microscopy
2019 · Arianna Fumagalli, Lotte Bruens, et al. · Cold Spring Harbor Perspectives in Biology · 11
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Cellular protection mechanisms that minimise accumulation of mutations in intestinal tissue
2017 · Lotte Bruens, Jacco Van Rheenen · Swiss Medical Weekly · 8
Expanding the Tissue Toolbox: Deriving Colon Tissue from Human Pluripotent Stem Cells
2017 · Lotte Bruens, Hugo J.G. Snippert · Cell stem cell · 4
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Author response: Mother cells control daughter cell proliferation in intestinal organoids to minimize proliferation fluctuations
2022 · Guizela Huelsz-Prince, Rutger Nico Ulbe Kok, et al. · 1
Code and data from "Mother cells control daughter cell proliferation in intestinal organoids to minimize proliferation fluctuations"
2022 · Huelsz-Prince, Guizela, Kok, Rutger N.U., et al. · Zenodo (CERN European Organization for Nuclear Research)
In vivo visualization of intestinal stem cell and crypt dynamics
2020 · Bruens, Lotte
The role of receptor-associated E3 ligases in WNT signaling and disease
2014 · Lotte Bruens · Utrecht University Repository (Utrecht University)
Works count: 14
Citation count: 832
H-index: 8
I10-index: 8
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