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Sita Kugel Desmoulin

Observed names: Desmoulin, Sita, S Kugel Desmoulin, Sita Desmoulin, Sita Kugel-Desmoulin
OpenAlex ID: A5059629890
The human proton-coupled folate transporter
2012 · Sita Kugel Desmoulin, Zhanjun Hou, et al. · Cancer Biology & Therapy · 155
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The impact of NOTCH1, FBW7 and PTEN mutations on prognosis and downstream signaling in pediatric T-cell acute lymphoblastic leukemia: a report from the Children's Oncology Group
2009 · A Larson Gedman, Q Chen, et al. · Leukemia · 136
Synthesis and Biological Activity of a Novel Series of 6-Substituted Thieno[2,3-d]pyrimidine Antifolate Inhibitors of Purine Biosynthesis with Selectivity for High Affinity Folate Receptors over the Reduced Folate Carrier and Proton-Coupled Folate Transporter for Cellular Entry†
2009 · Yijun Deng, Xilin Zhou, et al. · Journal of Medicinal Chemistry · 80
Synthesis, Biological, and Antitumor Activity of a Highly Potent 6-Substituted Pyrrolo[2,3-d]pyrimidine Thienoyl Antifolate Inhibitor with Proton-Coupled Folate Transporter and Folate Receptor Selectivity over the Reduced Folate Carrier That Inhibits β-Glycinamide Ribonucleotide Formyltransferase
2011 · Lei Wang, Sita Kugel Desmoulin, et al. · Journal of Medicinal Chemistry · 70
Synthesis and Antitumor Activity of a Novel Series of 6-Substituted Pyrrolo[2,3-d]pyrimidine Thienoyl Antifolate Inhibitors of Purine Biosynthesis with Selectivity for High Affinity Folate Receptors and the Proton-Coupled Folate Transporter over the Reduced Folate Carrier for Cellular Entry
2010 · Lei Wang, Christina Cherian, et al. · Journal of Medicinal Chemistry · 66
Therapeutic Targeting of a Novel 6-Substituted Pyrrolo [2,3-d]pyrimidine Thienoyl Antifolate to Human Solid Tumors Based on Selective Uptake by the Proton-Coupled Folate Transporter
2011 · Sita Kugel Desmoulin, Lei Wang, et al. · Molecular Pharmacology · 61
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Synergistic effects of multiple natural products in pancreatic cancer cells
2008 · Zhiwei Wang, Sita Desmoulin, et al. · Life Sciences · 60
Targeting the Proton-Coupled Folate Transporter for Selective Delivery of 6-Substituted Pyrrolo[2,3-d]Pyrimidine Antifolate Inhibitors of De Novo Purine Biosynthesis in the Chemotherapy of Solid Tumors
2010 · Sita Kugel Desmoulin, Yiqiang Wang, et al. · Molecular Pharmacology · 54
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Synthesis and Biological Activity of 6-Substituted Pyrrolo[2,3-d]pyrimidine Thienoyl Regioisomers as Inhibitors of de Novo Purine Biosynthesis with Selectivity for Cellular Uptake by High Affinity Folate Receptors and the Proton-Coupled Folate Transporter over the Reduced Folate Carrier
2012 · Lei Wang, Christina Cherian, et al. · Journal of Medicinal Chemistry · 44
Identification and Functional Impact of Homo-oligomers of the Human Proton-coupled Folate Transporter
2011 · Zhanjun Hou, Sita Kugel Desmoulin, et al. · Journal of Biological Chemistry · 35
Functional Loss of the Reduced Folate Carrier Enhances the Antitumor Activities of Novel Antifolates with Selective Uptake by the Proton-Coupled Folate Transporter
2012 · Sita Kugel Desmoulin, Lei Wang, et al. · Molecular Pharmacology · 30
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Therapeutic targeting malignant mesothelioma with a novel 6-substituted pyrrolo[2,3-d]pyrimidine thienoyl antifolate via its selective uptake by the proton-coupled folate transporter
2013 · Christina Cherian, Sita Kugel Desmoulin, et al. · Cancer Chemotherapy and Pharmacology · 22
Abstract 4546: Expression profiling of the major folate facilitative transporters in human tumors and normal tissues
2010 · Sita Kugel-Desmoulin, Lei Wang, et al. · Cancer Research · 2
Abstract 783: Identification of structural determinants of human proton-coupled folate transporter oligomerization
2014 · Zhanjun Hou, M. Roy Wilson, et al. · Cancer Research
Abstract 3826: Therapeutic targeting malignant mesothelioma with a novel 6-substituted pyrrolo[2,3-d]pyrimidine thienoyl antifolate via its selective uptake by the proton-coupled folate transporter
2012 · Christina Cherian, Sita Kugel Desmoulin, et al. · Cancer Research
Abstract 3825: The impact of the reduced folate carrier on the collateral sensitivity of novel 6-substituted pyrrolo[2,3-d]pyrimidine thienoyl antifolates with selective uptake by the proton-coupled folate transporter
2012 · Sita Kugel Desmoulin, Lei Wang, et al. · Cancer Research
Abstract 3250: Design, synthesis and biological evaluation of side chain pemetrexed (PMX) analogues as potent inhibitors of tumors expressing folate receptors via GARFTase inhibition
2011 · Yiqiang Wang, Shermaine Mitchell, et al. · Cancer Research
Abstract 1364: Design, synthesis and evaluation of potent antiproliferative and cytotoxic antifolates with selective FRs and PCFT transport over RFC and potent GARFTase inhibition
2011 · Lei Wang, Christina Cherian, et al. · Cancer Research
Abstract 2528: Therapeutic targeting of a novel 6-substituted pyrrolo[2,3-d]pyrimidine thienoyl antifolate to human solid tumors based on selective uptake by PCFT
2011 · Sita Kugel Desmoulin, Lei Wang, et al. · Cancer Research
Abstract 4542: The design, synthesis and in vitro evaluation of selective FR α and β and PCFT substrates with potent GARFTase inhibitory activity as antitumor agents
2010 · Aleem Gangjee, Lei Wang, et al. · Cancer Research
Abstract #1684: Discovery of a glycinamide ribonucleotide formyltransferase inhibitor with solid tumor selectivity via its transport by the proton-coupled folate transporter
2009 · Sita Kugel Desmoulin, Yiqiang Wang, et al. · Cancer Research
Works count: 25
Citation count: 815
H-index: 12
I10-index: 12
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