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Author

Carl Diehl

Observed names: C. Diehl, Diehl, Carl
Observed institutions: University of Copenhagen, Lund University, Novo Nordisk Foundation, Medicon Village, SARomics Biostructures (Sweden), Bayer (Germany)
ORCID: 0000-0002-0959-6459
Observed ORCID: 0000-0002-0959-6459
OpenAlex ID: A5059896575
Protein Flexibility and Conformational Entropy in Ligand Design Targeting the Carbohydrate Recognition Domain of Galectin-3
2010 · Carl Diehl, Olof Engström, et al. · Journal of the American Chemical Society · 235
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The Carbohydrate-Binding Site in Galectin-3 Is Preorganized To Recognize a Sugarlike Framework of Oxygens: Ultra-High-Resolution Structures and Water Dynamics
2011 · Kadhirvel Saraboji, Maria Håkansson, et al. · Biochemistry · 171
Conformational entropy changes upon lactose binding to the carbohydrate recognition domain of galectin-3
2009 · Carl Diehl, Samuel Genheden, et al. · Journal of Biomolecular NMR · 85
Starting-Condition Dependence of Order Parameters Derived from Molecular Dynamics Simulations
2010 · Samuel Genheden, Carl Diehl, et al. · Journal of Chemical Theory and Computation · 39
Structural Analysis of a Complex between Small Ubiquitin-like Modifier 1 (SUMO1) and the ZZ Domain of CREB-binding Protein (CBP/p300) Reveals a New Interaction Surface on SUMO
2016 · Carl Diehl, Mikael Akke, et al. · Journal of Biological Chemistry · 38
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Discovery of the Selective and Orally Available Galectin-1 Inhibitor GB1908 as a Potential Treatment for Lung Cancer
2024 · Fredrik R. Zetterberg, Kristoffer Peterson, et al. · Journal of Medicinal Chemistry · 34
Ligand-induced protein transition state stabilization switches the binding pathway from conformational selection to induced fit
2024 · Olof Stenström, Carl Diehl, et al. · Proceedings of the National Academy of Sciences · 34
Benzimidazole–galactosides bind selectively to the Galectin-8 N-Terminal domain: Structure-based design and optimisation
2021 · Mujtaba Hassan, Sjors van Klaveren, et al. · European Journal of Medicinal Chemistry · 27
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13C relaxation experiments for aromatic side chains employing longitudinal- and transverse-relaxation optimized NMR spectroscopy
2012 · Ulrich Weininger, Carl Diehl, et al. · Journal of Biomolecular NMR · 27
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Discovery of Selective and Orally Available Galectin-1 Inhibitors
2023 · Fredrik R. Zetterberg, Carl Diehl, et al. · Journal of Medicinal Chemistry · 23
Structural basis for the antiarrhythmic blockade of a potassium channel with a small molecule
2017 · Yoshio Takemoto, Diana P. Slough, et al. · The FASEB Journal · 23
Protein loop compaction and the origin of the effect of arginine and glutamic acid mixtures on solubility, stability and transient oligomerization of proteins
2011 · Jascha Blobel, Ulrika Brath, et al. · European Biophysics Journal · 20
Conformational Entropy of FK506 Binding to FKBP12 Determined by Nuclear Magnetic Resonance Relaxation and Molecular Dynamics Simulations
2018 · Gleb Solomentsev, Carl Diehl, et al. · Biochemistry · 18
Isolation, Characterization and Structure Elucidation of a Novel Lantibiotic From Paenibacillus sp.
2020 · Jerzy Karczewski, Stephen P. Krasucki, et al. · Frontiers in Microbiology · 16
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Mapping the energy landscape of protein–ligand binding via linear free energy relationships determined by protein NMR relaxation dispersion
2020 · Olof Stenström, Carl Diehl, et al. · RSC Chemical Biology · 15
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pKa Values for the Unfolded State under Native Conditions Explain the pH-Dependent Stability of PGB1
2010 · Stina Lindman, Mikael C. Bauer, et al. · Biophysical Journal · 14
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Targeting Toll-like receptor-driven systemic inflammation by engineering an innate structural fold into drugs
2023 · Ganna Petruk, Manoj Puthia, et al. · Nature Communications · 13
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An integrative toolbox to unlock the structure and dynamics of protein–surfactant complexes
2020 · Adrian Sanchez-Fernandez, Carl Diehl, et al. · Nanoscale Advances · 13
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Modulating protein unfolding and refolding via the synergistic association of an anionic and a nonionic surfactant
2024 · Johanna Hjalte, Carl Diehl, et al. · Journal of Colloid and Interface Science · 10
Beyond identity: Understanding the contribution of the 5’ nucleotide of the antisense strand to RNAi activity
2021 · Peizhen Yang, Ericka Havecker, et al. · PLoS ONE · 3
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An Orally Available Halothiazole Glycomimetic as a Cancer-Targeting Dual Galectin-1 and Galectin-3 Inhibitor
2026 · Fredrik R. Zetterberg, Kristoffer Peterson, et al. · Journal of Medicinal Chemistry · 2
Excipient effect on phenol-induced precipitation of human growth hormone and bovine serum albumin
2025 · Johanna Hjalte, Anna-Maria Börjesdotter, et al. · International Journal of Pharmaceutics · 2
Structure and Interactions of a Dimeric Variant of sHIP, a Novel Virulence Determinant of Streptococcus pyogenes
2016 · Carl Diehl, Magdalena Wisniewska, et al. · Frontiers in Microbiology · 2
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Complementation of 3D structure of delta subunit of RNA polymerase from Bacillus subtilis with description of internal motions in terms of reduced spectral density mapping
2011 · Pavel Kadeřávek, Carl Diehl, et al. · 2
The Effect of Pharmaceutical Excipients on Protein Chemical Degradation Through Deamidation and Isomerization
2026 · Ingrid Ramm, Carl Diehl, et al. · Pharmaceutical Research · 1
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Works count: 40
Citation count: 870
H-index: 15
I10-index: 19
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