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Araz Eivazi
Institution:
Xencor (United States)
Observed institution:
Xencor (United States)
ORCID:
0009-0006-8468-253X
Observed ORCID:
0009-0006-8468-253X
OpenAlex ID:
A5060094291
Engineered antibody Fc variants with enhanced effector function
2006
·
Greg A. Lazar
, Wei Dang
, et al.
·
Proceedings of the National Academy of Sciences
·
826
Inactivation of TNF Signaling by Rationally Designed Dominant-Negative TNF Variants
2003
·
Paul M. Steed
, Malú G. Tansey
, et al.
·
Science
·
256
Dominant-Negative Inhibitors of Soluble TNF Attenuate Experimental Arthritis without Suppressing Innate Immunity to Infection
2007
·
Jonathan Zalevsky
, Thomas Secher
, et al.
·
The Journal of Immunology
·
160
A novel bispecific antibody format enables simultaneous bivalent and monovalent co-engagement of distinct target antigens
2011
·
Gregory L. Moore
, Cristina Bautista
, et al.
·
mAbs
·
110
PDF
A robust heterodimeric Fc platform engineered for efficient development of bispecific antibodies of multiple formats
2018
·
Gregory L. Moore
, Matthew J. Bernett
, et al.
·
Methods
·
74
PDF
A B7-H3–Targeted CD28 Bispecific Antibody Enhances the Activity of Anti–PD-1 and CD3 T-cell Engager Immunotherapies
2024
·
Gregory L. Moore
, Veronica G. Zeng
, et al.
·
Molecular Cancer Therapeutics
·
21
PDF
Abstract 1860: Bispecific claudin-6 x CD3 antibodies in a 2 + 1 format demonstrate selectivity and activity on human ovarian cancer cells
2021
·
Matthew S. Faber
, Sung-Hyung Lee
, et al.
·
Cancer Research
·
8
707 IL12 Fc-fusions engineered for reduced potency and extended half-life exhibit strong anti-tumor activity and improved therapeutic index compared to wild-type IL12 agents
2021
·
Matthew Bernett
, Ke Liu
, et al.
·
Journal for ImmunoTherapy of Cancer
·
1
PDF
CD2 x IL2RG bispecific antibodies synergistically modulate lymphocyte activation, resulting in suppression of inflammation and prevention of GVHD 2258985
2026
·
Ke Liu
, Michael Cadell
, et al.
·
The Journal of Immunology
PDF
Figure 3 from A B7-H3–Targeted CD28 Bispecific Antibody Enhances the Activity of Anti–PD-1 and CD3 T-cell Engager Immunotherapies
2025
·
Gregory L. Moore
, Veronica G. Zeng
, et al.
Figure 4 from A B7-H3–Targeted CD28 Bispecific Antibody Enhances the Activity of Anti–PD-1 and CD3 T-cell Engager Immunotherapies
2025
·
Gregory L. Moore
, Veronica G. Zeng
, et al.
Figure 5 from A B7-H3–Targeted CD28 Bispecific Antibody Enhances the Activity of Anti–PD-1 and CD3 T-cell Engager Immunotherapies
2025
·
Gregory L. Moore
, Veronica G. Zeng
, et al.
Figure 1 from A B7-H3–Targeted CD28 Bispecific Antibody Enhances the Activity of Anti–PD-1 and CD3 T-cell Engager Immunotherapies
2025
·
Gregory L. Moore
, Veronica G. Zeng
, et al.
Figure 6 from A B7-H3–Targeted CD28 Bispecific Antibody Enhances the Activity of Anti–PD-1 and CD3 T-cell Engager Immunotherapies
2025
·
Gregory L. Moore
, Veronica G. Zeng
, et al.
Supplementary Figure S1 from A B7-H3–Targeted CD28 Bispecific Antibody Enhances the Activity of Anti–PD-1 and CD3 T-cell Engager Immunotherapies
2025
·
Gregory L. Moore
, Veronica G. Zeng
, et al.
Supplementary Figure S2 from A B7-H3–Targeted CD28 Bispecific Antibody Enhances the Activity of Anti–PD-1 and CD3 T-cell Engager Immunotherapies
2025
·
Gregory L. Moore
, Veronica G. Zeng
, et al.
Data from A B7-H3–Targeted CD28 Bispecific Antibody Enhances the Activity of Anti–PD-1 and CD3 T-cell Engager Immunotherapies
2025
·
Gregory L. Moore
, Veronica G. Zeng
, et al.
Figure 2 from A B7-H3–Targeted CD28 Bispecific Antibody Enhances the Activity of Anti–PD-1 and CD3 T-cell Engager Immunotherapies
2025
·
Gregory L. Moore
, Veronica G. Zeng
, et al.
Abstract 3515: Engineered IL18 heterodimeric Fc-fusions featuring improved stability, reduced potency, and insensitivity to IL18BP
2022
·
Alex Nisthal
, Sung-Hyung Lee
, et al.
·
Cancer Research
Abstract 1743: IL12 heterodimeric Fc-fusions engineered for reduced potency exhibit strong anti-tumor activity and improved therapeutic index compared to native IL12 agents
2021
·
Matthew J. Bernett
, Ke Liu
, et al.
·
Cancer Research
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Works count:
20
Citation count:
1,456
H-index:
7
I10-index:
6
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