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Sebastian Oehler

Observed names: Oehler, Sebastian, Oehler, Sebastian R., S Oehler, S. Oehler, Sebastian R. Oehler
ORCID: 0000-0003-2013-7381
Observed ORCID: 0000-0003-2013-7381
OpenAlex ID: A5060108598
Platform for Orthogonal N-Cysteine-Specific Protein Modification Enabled by Cyclopropenone Reagents
2022 · Alena Istrate, Michael B. Geeson, et al. · Journal of the American Chemical Society · 83
A DNA‐Encoded Chemical Library Based on Peptide Macrocycles
2021 · Yuichi Onda, Gabriele Bassi, et al. · Chemistry - A European Journal · 53
Selective tumor targeting enabled by picomolar fibroblast activation protein inhibitors isolated from a DNA-encoded affinity maturation library
2022 · Sara Puglioli, Eleonore Schmidt, et al. · Chem · 47
Cross-reactivity to glutamate carboxypeptidase III causes undesired salivary gland and kidney uptake of PSMA-targeted small-molecule radionuclide therapeutics
2022 · Laura Lucaroni, Tony Georgiev, et al. · European Journal of Nuclear Medicine and Molecular Imaging · 45
A DNA-encoded chemical library based on chiral 4-amino-proline enables stereospecific isozyme-selective protein recognition
2023 · Sebastian Oehler, Laura Lucaroni, et al. · Nature Chemistry · 44
Affinity Selections of DNA‐Encoded Chemical Libraries on Carbonic Anhydrase IX‐Expressing Tumor Cells Reveal a Dependence on Ligand Valence
2021 · Sebastian Oehler, Marco Catalano, et al. · Chemistry - A European Journal · 34
Discovery of high-affinity ligands for prostatic acid phosphatase via DNA-encoded library screening enables targeted cancer therapy
2025 · Tony Georgiev, Francesca Migliorini, et al. · Nature Biomedical Engineering · 30
Small Organic Carbonic Anhydrase IX Ligands from DNA-Encoded Chemical Libraries for Tumor-Targeted Delivery of Radionuclides
2025 · Marco Müller, Tony Georgiev, et al. · Journal of the American Chemical Society · 28
Comparative evaluation of DNA-encoded chemical selections performed using DNA in single-stranded or double-stranded format
2020 · Gabriele Bassi, Nicholas Favalli, et al. · Biochemical and Biophysical Research Communications · 27
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Deep Learning Approach for the Discovery of Tumor-Targeting Small Organic Ligands from DNA-Encoded Chemical Libraries
2023 · Wen Torng, Ilaria Biancofiore, et al. · ACS Omega · 25
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Universal encoding of next generation DNA-encoded chemical libraries
2022 · Louise Plais, Alice Lessing, et al. · Chemical Science · 24
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Modular assembly and encoding strategies for dual-display DNA-encoded chemical libraries
2021 · Sebastian Oehler, Louise Plais, et al. · Chemical Communications · 17
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Complexation with a Cognate Antibody Fragment Facilitates Affinity Measurements of Fluorescein-Linked Small Molecule Ligands
2020 · Marco Catalano, Sebastian Oehler, et al. · Analytical Chemistry · 17
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Translational and First-in-Human Positron Emission Tomography Targeting Prostatic Acid Phosphatase in Prostate Cancer Using the Ligand [68Ga]Ga-OncoACP3-DOTA
2025 · Philipp Backhaus, Samuele Cazzamalli, et al. · European Urology · 15
Impact of library input on the hit discovery rate in DNA-encoded chemical library selections
2023 · Sara Puglioli, Sebastian Oehler, et al. · Chemical Science · 12
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Discovery of Glutamate Carboxypeptidase III Ligands to Compete the Uptake of [ 177 Lu]Lu-PSMA-617 in Healthy Organs
2024 · Marco Müller, Laura Lucaroni, et al. · Journal of Medicinal Chemistry · 11
Science of Synthesis
2015 · J. Scheuermann, Y. Li, et al. · Science of synthesis · 11
Native Mass Spectrometry Facilitates Hit Validation in DNA‐Encoded Library Technology
2025 · Philipp Bittner, Andreas Gloger, et al. · Angewandte Chemie International Edition · 10
DNA-encoded chemical libraries enable the discovery of potent PSMA-ligands with substantially reduced affinity towards the GCPIII anti-target
2024 · Laura Lucaroni, Sebastian Oehler, et al. · Chemical Science · 8
Phenylalanine‐Based DNA‐Encoded Chemical Libraries for the Discovery of Potent and Selective Small Organic Ligands Against Markers of Cancer and Immune Cells
2025 · Francesca Migliorini, Andrea Ciamarone, et al. · Advanced Science · 6
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The Influence of Single-Stranded or Double-Stranded DNA Tags on Ligand Binding Affinity in DNA-Encoded Libraries
2025 · Philipp Bittner, Andreas Gloger, et al. · Analytical Chemistry · 4
Response to: GCP III is not the “off-target” for urea-based PSMA-ligands
2023 · Gabriele Bassi, Samuele Cazzamalli, et al. · European Journal of Nuclear Medicine and Molecular Imaging · 3
Isolation of a Natural Killer Group 2D Small‐Molecule Ligand from DNA‐Encoded Chemical Libraries
2022 · Sheila Dakhel, Andrea Galbiati, et al. · ChemMedChem · 3
[68Ga]Ga-OncoACP3 PET imaging defines acid phosphatase 3 as a clinically actionable theranostic target in prostate cancer: a prospective phase I trial
2026 · Martina Sollini, Fabrizia Gelardi, et al. · The EANM Journal · 1
Diagnostic performance, safety, and biodistribution of [ 68 Ga]Ga-OncoCAIX for PET/CT imaging: A first-in-human phase I clinical trial in clear cell renal cell carcinoma.
2026 · Fabrizia Gelardi, Martina Sollini, et al. · Journal of Clinical Oncology · 1
Works count: 41
Citation count: 565
H-index: 14
I10-index: 18
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