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Author

Florian Klemm

Observed names: F. Klemm, Klemm, Florian
Observed institutions: Memorial Sloan Kettering Cancer Center, Universitätsmedizin Göttingen, Ludwig Cancer Research, Sophia Genetics (Switzerland), University of Göttingen, University of Lausanne
ORCID: 0000-0002-8944-9175
Observed ORCID: 0000-0002-8944-9175
OpenAlex ID: A5060305611
Interrogation of the Microenvironmental Landscape in Brain Tumors Reveals Disease-Specific Alterations of Immune Cells
2020 · Florian Klemm, Roeltje R. Maas, et al. · Cell · 1,076
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Microenvironmental regulation of therapeutic response in cancer
2014 · Florian Klemm, Johanna A. Joyce · Trends in Cell Biology · 799
Macrophage Ontogeny Underlies Differences in Tumor-Specific Education in Brain Malignancies
2016 · Robert L. Bowman, Florian Klemm, et al. · Cell Reports · 649
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Macrophages Induce Invasiveness of Epithelial Cancer Cells Via NF-κB and JNK
2005 · Thorsten Hagemann, Julia Wilson, et al. · The Journal of Immunology · 444
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Wnt 5a signaling is critical for macrophage-induced invasion of breast cancer cell lines
2006 · T. Pukrop, F. Klemm, et al. · Proceedings of the National Academy of Sciences · 368
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Dynamic changes in glioma macrophage populations after radiotherapy reveal CSF-1R inhibition as a strategy to overcome resistance
2020 · Leila Akkari, Robert L. Bowman, et al. · Science Translational Medicine · 331
Microglia promote colonization of brain tissue by breast cancer cells in a Wnt‐dependent way
2010 · Tobias Pukrop, Faramarz Dehghani, et al. · Glia · 236
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Tumor-derived microvesicles mediate human breast cancer invasion through differentially glycosylated EMMPRIN
2014 · Kerstin Menck, Christian Scharf, et al. · Journal of Molecular Cell Biology · 147
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Compensatory CSF2-driven macrophage activation promotes adaptive resistance to CSF1R inhibition in breast-to-brain metastasis
2021 · Florian Klemm, Aylin Möckl, et al. · Nature Cancer · 142
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β-catenin-independent WNT signaling in basal-like breast cancer and brain metastasis
2010 · F. Klemm, A. Bleckmann, et al. · Carcinogenesis · 140
Induction and transport of Wnt 5a during macrophage-induced malignant invasion is mediated by two types of extracellular vesicles
2013 · Kerstin Menck, Florian Klemm, et al. · Oncotarget · 137
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The metastatic infiltration at the metastasis/brain parenchyma-interface is very heterogeneous and has a significant impact on survival in a prospective study
2015 · Laila Siam, Annalen Bleckmann, et al. · Oncotarget · 114
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Isolation of Human Monocytes by Double Gradient Centrifugation and Their Differentiation to Macrophages in Teflon-coated Cell Culture Bags
2014 · Kerstin Menck, Daniel Behme, et al. · Journal of Visualized Experiments · 111
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Characterisation of tumour‐derived microvesicles in cancer patients' blood and correlation with clinical outcome
2017 · Kerstin Menck, Annalen Bleckmann, et al. · Journal of Extracellular Vesicles · 109
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Comparative study on gene set and pathway topology-based enrichment methods
2015 · Michaela Bayerlová, Klaus Jung, et al. · BMC Bioinformatics · 90
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Carcinoma cells misuse the host tissue damage response to invade the brain
2013 · Han‐Ning Chuang, Denise van Rossum, et al. · Glia · 78
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Ror2 Signaling and Its Relevance in Breast Cancer Progression
2017 · Michaela Bayerlová, Kerstin Menck, et al. · Frontiers in Oncology · 55
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Immunogenomic analysis of human brain metastases reveals diverse immune landscapes across genetically distinct tumors
2023 · Ángel F. Álvarez-Prado, Roeltje R. Maas, et al. · Cell Reports Medicine · 51
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Nuclear LEF1/TCF4 correlate with poor prognosis but not with nuclear β-catenin in cerebral metastasis of lung adenocarcinomas
2012 · A. Bleckmann, L. Siam, et al. · Clinical & Experimental Metastasis · 47
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Iron imaging reveals tumor and metastasis macrophage hemosiderin deposits in breast cancer
2017 · Avigdor Leftin, Nir Ben-Chetrit, et al. · PLoS ONE · 45
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The anthelmintic niclosamide inhibits colorectal cancer cell lines via modulation of the canonical and noncanonical Wnt signaling pathway
2016 · Malte B. Monin, Petra Krause, et al. · Journal of Surgical Research · 42
β-catenin-independent WNT signaling and Ki67 in contrast to the estrogen receptor status are prognostic and associated with poor prognosis in breast cancer liver metastases
2016 · Annalen Bleckmann, Lena-Christin Conradi, et al. · Clinical & Experimental Metastasis · 41
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rBiopaxParser—an R package to parse, modify and visualize BioPAX data
2012 · Frank Kramer, Michaela Bayerlová, et al. · Bioinformatics · 37
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Newly Constructed Network Models of Different WNT Signaling Cascades Applied to Breast Cancer Expression Data
2015 · Michaela Bayerlová, Florian Klemm, et al. · PLoS ONE · 21
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Evaluating Magnetic Resonance Spectroscopy as a Tool for Monitoring Therapeutic Response of Whole Brain Radiotherapy in a Mouse Model for Breast-to-Brain Metastasis
2019 · Woon Hyung Chae, Katja Niesel, et al. · Frontiers in Oncology · 19
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Works count: 57
Citation count: 5,378
H-index: 23
I10-index: 28
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