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Christophe Chassagnole

Dynamic modeling of the central carbon metabolism of Escherichia coli
2002 · Christophe Chassagnole, Naruemol Noisommit‐Rizzi, et al. · Biotechnology and Bioengineering · 552
Rational Design of a Corynebacterium glutamicum Pantothenate Production Strain and Its Characterization by Metabolic Flux Analysis and Genome-Wide Transcriptional Profiling
2005 · Andrea T. Hüser, Christophe Chassagnole, et al. · Applied and Environmental Microbiology · 110
An integrated study of threonine-pathway enzyme kinetics in Escherichia coli
2001 · Christophe CHASSAGNOLE, Badr RAÏS, et al. · Biochemical Journal · 83
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Control of the threonine-synthesis pathway in Escherichia coli: a theoretical and experimental approach
2001 · Christophe CHASSAGNOLE, David A. FELL, et al. · Biochemical Journal · 69
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Metabolic network analysis during fed-batch cultivation of Corynebacterium glutamicum for pantothenic acid production: first quantitative data and analysis of by-product formation
2003 · Christophe Chassagnole, Audrey Diano, et al. · Journal of Biotechnology · 44
Ketopantoate reductase activity is only encoded by ilvC in Corynebacterium glutamicum
2003 · Muriel Merkamm, Christophe Chassagnole, et al. · Journal of Biotechnology · 39
Using a mammalian cell cycle simulation to interpret differential kinase inhibition in anti-tumour pharmaceutical development
2005 · C. Chassagnole, R.C. Jackson, et al. · Biosystems · 36
Carbon Flux Analysis in a Pantothenate Overproducing Corynebacterium Glutamicum Strain
2002 · Christophe Chassagnole, Fabien Létisse, et al. · Molecular Biology Reports · 24
Threonine synthesis from aspartate in Escherichia coli cell-free extracts: pathway dynamics
2001 · Badr RAÏS, Christophe CHASSAGNOLE, et al. · Biochemical Journal · 23
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In silico strategy to rationally engineer metabolite production: A case study for threonine in Escherichia coli
2009 · Juan‐Carlos Rodríguez‐Prados, Pedro de Atauri, et al. · Biotechnology and Bioengineering · 17
Dynamic simulation of pollutant effects on the threonine pathway in Escherichia coli
2003 · Christophe Chassagnole, Éric Quentin, et al. · Comptes Rendus Biologies · 12
Differential Evolutionary Algorithms for In Vivo Dynamic Analysis of Glycolysis and Pentose Phosphate Pathway in Escherichia coli
2005 · Christophe Chassagnole, Juan‐Carlos A. Rodriguez, et al. · 8
Semi-mechanistic efficacy model for PARP + ATR inhibitors—application to rucaparib and talazoparib in combination with gartisertib in breast cancer PDXs
2025 · Claire C. Villette, Nathalie Dupuy, et al. · British Journal of Cancer · 6
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A Multiple‐Model‐Informed Drug‐Development Approach for Optimal Regimen Selection of an Oncolytic Virus in Combination With Pembrolizumab
2025 · Akihiro Yamada, Mary P. Choules, et al. · CPT Pharmacometrics & Systems Pharmacology · 5
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Abstract 4918: Predicting the effect of drug combination schedules on xenograft growth using the Virtual Tumor
2011 · David Orrell, Eric Fernandez, et al. · Cancer Research · 3
In silico strategy to rationally engineer metabolite production: a case study for threonine in Escherichia coli
2009 · P. De Atauri, J.C. Rodríguez-Prados, et al. · New Biotechnology · 3
Control of threonine pathway in E. coli. application to biotechnologies
1995 · B. Ra�s, C. Chassagnole, et al. · Acta Biotheoretica · 3
A Pharmacokinetic and Pharmacodynamic Model of an IL-12 Anchored-Drug Conjugate for the Treatment of Solid Tumors
2025 · Hitesh B. Mistry, David Hodson, et al. · Molecular Cancer Therapeutics · 2
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Abstract 5699: Development and validation of a quantitative systems pharmacology model for prediction of preclinical efficacy of PARP inhibitors rucaparib and talazoparib combined with the ATR inhibitor gartisertib (M4344)
2023 · Claire C. Villette, Frances Brightman, et al. · Cancer Research · 2
Abstract LB-392: Optimizing dual immuno-oncology combinations with a virtual tumor
2020 · Fernando Ortega, Frances A. Brightman, et al. · Cancer Research · 2
Abstract 5147: drugCARD: a database of anticancer treatment regimens and drug combinations.
2013 · Eric Fernandez, Jianxiong Pang, et al. · Cancer Research · 2
Parameters estimation by differential evolutionary algorithms for simulation of metabolic pathways in Escherichia coli
2006 · C. Chassagnole, L. Manyri, et al. · International Conference on Advanced Information Networking and Applications (AINA) · 2
Dependence of Control Coefficient Distribution on the Boundaries of a Metabolic System: A Generalized Analysis of the Effects of Additional Input and Output reactions to a Linear Pathway
2002 · PEDRO DE ATAURI, DAVID A. FELL, et al. · Journal of Theoretical Biology · 2
Should personalised dosing have a role in cancer treatment?
2023 · Claire C. Villette, David Orrell, et al. · Frontiers in Oncology · 1
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Abstract 228: A precision dosing application for patients treated with docetaxel and G-CSF
2021 · Christian Hurry, Claire Villette, et al. · Cancer Research · 1
Works count: 63
Citation count: 1,061
H-index: 11
I10-index: 11
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