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Hervé Poras

Observed names: H. PORAS, H. Poras, HERVÉ PORAS, Herve Poras, Herve ́ Poras, Hervé Poras, Poras Hervé, Poras, H., Poras, Hervé
ORCID: 0000-0002-3329-7432
Observed ORCID: 0000-0002-3329-7432
OpenAlex ID: A5060369838
New Orally Active Dual Enkephalinase Inhibitors (DENKIs) for Central and Peripheral Pain Treatment
2014 · Hervé Poras, Elisabeth Bonnard, et al. · Journal of Medicinal Chemistry · 52
Dual enkephalinase inhibitor PL265: a novel topical treatment to alleviate corneal pain and inflammation
2018 · Annabelle Reaux-Le Goazigo, Hervé Poras, et al. · Pain · 39
Detection and Quantification of Botulinum Neurotoxin Type A by a Novel Rapid In Vitro Fluorimetric Assay
2009 · Hervé Poras, Tanja Ouimet, et al. · Applied and Environmental Microbiology · 32
Structure of aminopeptidase N fromEscherichia colicomplexed with the transition-state analogue aminophosphinic inhibitor PL250
2009 · Marie-Claude Fournié-Zaluski, Hervé Poras, et al. · Acta Crystallographica Section D Biological Crystallography · 30
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Synergistic combinations of the dual enkephalinase inhibitor PL265 given orally with various analgesic compounds acting on different targets, in a murine model of cancer-induced bone pain
2016 · Sara González-Rodríguez, Hervé Poras, et al. · Scandinavian Journal of Pain · 26
Long‐lasting oral analgesic effects ofN‐protected aminophosphinic dual ENK ephalinase inhibitors ( DENKI s) in peripherally controlled pain
2015 · Elisabeth Bonnard, Hervé Poras, et al. · Pharmacology Research & Perspectives · 25
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N-[2-(Indan-1-yl)-3-mercapto-propionyl] amino acids as highly potent inhibitors of the three vasopeptidases (NEP, ACE, ECE): In vitro and In vivo activities
2002 · Nicolas Inguimbert, Hervé Poras, et al. · Bioorganic & Medicinal Chemistry Letters · 25
Inhibition of osteosarcoma-induced thermal hyperalgesia in mice by the orally active dual enkephalinase inhibitor PL37. Potentiation by gabapentin
2008 · Luis Menéndez, Agustín Hidalgo, et al. · European Journal of Pharmacology · 23
Toward an Optimal Joint Recognition of the S1‘ Subsites of Endothelin Converting Enzyme-1 (ECE-1), Angiotensin Converting Enzyme (ACE), and Neutral Endopeptidase (NEP)
2002 · Nicolas Inguimbert, Pascale Coric, et al. · Journal of Medicinal Chemistry · 23
Preventive and alleviative effects of the dual enkephalinase inhibitor (Denki) PL265 in a murine model of neuropathic pain
2016 · Elisabeth Bonnard, Hervé Poras, et al. · European Journal of Pharmacology · 20
The inhibition of enkephalin catabolism by dual enkephalinase inhibitor: A novel possible therapeutic approach for opioid use disorders
2021 · Beltran Alvarez‐Perez, Hervé Poras, et al. · British Journal of Pharmacology · 19
Dual enkephalinase inhibitor PL37 as a potential novel treatment of migraine: evidence from a rat model
2022 · Amélie Descheemaeker, Hervé Poras, et al. · Brain · 18
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Synthesis and In Vitro Antibacterial Activity of Catechol-spiramycin Conjugates.
1998 · HERVÉ PORAS, GERHARD KUNESCH, et al. · The Journal of Antibiotics · 18
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Efficacy of dual enkephalinase inhibition in a preclinical migraine model is mediated by activation of peripheral delta opioid receptors
2023 · Hao‐Ruei Mei, Ya‐Yu Hu, et al. · Headache The Journal of Head and Face Pain · 16
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A sensitive fluorigenic substrate for selective in vitro and in vivo assay of leukotriene A4 hydrolase activity
2013 · Hervé Poras, Sophie Duquesnoy, et al. · Analytical Biochemistry · 13
Nucleophilic substitution of optically active 1-alkoxypolyfluoroalkyl sulfonates
1998 · Hiroshi Matsutani, Hervé Poras, et al. · Chemical Communications · 13
Asymmetric Synthesis of 1-Alkoxy-2,2,2-trifluoroethanol Derivatives
1998 · Hervé Poras, Hiroshi Matsutani, et al. · Chemistry Letters · 12
Comparison of Fluorigenic Peptide Substrates PL50, SNAPtide, and BoTest A/E for BoNT/A Detection and Quantification: Exosite Binding Confers High-Assay Sensitivity
2013 · Tanja Ouimet, Sophie Duquesnoy, et al. · SLAS DISCOVERY · 10
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Synergistic effect of combining dual enkephalinase inhibitor PL37 and sumatriptan in a preclinical model of migraine
2024 · Jeanne Rossignol, Tanja Ouimet, et al. · Headache The Journal of Head and Face Pain · 8
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Identification of an Endothelin-converting Enzyme-2-specific Fluorigenic Substrate and Development of an in Vitro and ex Vivo Enzymatic Assay
2010 · Tanja Ouimet, Sou-Vinh Orng, et al. · Journal of Biological Chemistry · 8
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Pluripotentialities of a quenched fluorescent peptide substrate library: enzymatic detection, characterization, and isoenzymes differentiation
2011 · Hervé Poras, Tanja Ouimet, et al. · Analytical Biochemistry · 7
Modulation of disulfide dual ENKephalinase inhibitors (DENKIs) activity by a transient N-protection for pain alleviation by oral route
2015 · Hervé Poras, Elisabeth Bonnard, et al. · European Journal of Medicinal Chemistry · 6
In vivo properties of thiol inhibitors of the three vasopeptidases NEP, ACE and ECE are improved by introduction of a 7‐azatryptophan in P2′ position
2004 · N. Inguimbert, H. Poras, et al. · Journal of Peptide Research · 6
Stereospecific Nucleophilic Substitution of Optically Active 1-Benzyloxy-2,2,2-trifluoroethyl Tosylate with Lithium Tetraalkylaluminates Prepared by the Ti-Catalyzed Hydroalumination of Olefins
1998 · Hiroshi Matsutani, Hervé Poras, et al. · Synlett · 6
Highly Sensitive Quenched Fluorescent Substrate of Legionella Major Secretory Protein (Msp) Based on Its Structural Analysis
2012 · Hervé Poras, Sophie Duquesnoy, et al. · Journal of Biological Chemistry · 4
Works count: 37
Citation count: 463
H-index: 14
I10-index: 18
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