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Fangye Gao

Increased Cardiac Expression of Tissue Inhibitor of Metalloproteinase-1 and Tissue Inhibitor of Metalloproteinase-2 Is Related to Cardiac Fibrosis and Dysfunction in the Chronic Pressure-Overloaded Human Heart
2005 · Stephane Heymans, Blanche Schroen, et al. · Circulation · 313
Insight into the mode of action of the LRRK2 Y1699C pathogenic mutant
2010 · Veronique Daniëls, Renée Vancraenenbroeck, et al. · Journal of Neurochemistry · 127
Inhibition of Urokinase-Type Plasminogen Activator or Matrix Metalloproteinases Prevents Cardiac Injury and Dysfunction During Viral Myocarditis
2006 · Stephane Heymans, Matthias Pauschinger, et al. · Circulation · 110
Biochemical Characterization of Highly Purified Leucine-Rich Repeat Kinases 1 and 2 Demonstrates Formation of Homodimers
2012 · Laura Civiero, Renée Vancraenenbroeck, et al. · PLoS ONE · 99
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Identification of protein phosphatase 1 as a regulator of the LRRK2 phosphorylation cycle
2013 · Evy Lobbestael, Jing Zhao, et al. · Biochemical Journal · 96
In silico, in vitro and cellular analysis with a kinome-wide inhibitor panel correlates cellular LRRK2 dephosphorylation to inhibitor activity on LRRK2
2014 · Renée Vancraenenbroeck, Joren De Raeymaecker, et al. · Frontiers in Molecular Neuroscience · 56
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Metabolic Labeling of Leucine Rich Repeat Kinases 1 and 2 with Radioactive Phosphate
2013 · Jean-Marc Taymans, Fangye Gao, et al. · Journal of Visualized Experiments · 5
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Long-Term Functional Correction of Pompe Disease and Increased α-Glucosidase Expression after Gene Therapy with Novel Combinations of Muscle-Targeted Transcriptional Cis -Regulatory Elements
2025 · Quang Hong Pham, Venkata Anudeep Bheemsetty, et al. · Human Gene Therapy · 3
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Metabolic Labeling of Leucine Rich Repeat Kinases 1 and 2 with Radioactive Phosphate
2013 · Jean-Marc Taymans, Fangye Gao, et al. · Journal of Visualized Experiments · 2
Increased gene therapy efficacy through the use of extended half-life clotting factors
2026 · Dries De Wolf, Phuong Anh Nguyen, et al. · Blood Advances · 1
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Dissection of the molecular mechanism of action of LRRK2 kinase inhibitors, a potential disease modifying treatment for PD
2013 · Jean‐Marc Taymans, Renée Vancraenenbroeck, et al. · Lirias
Combined in silico, in vitro and in cellulo analysis of ATP binding site kinase inhibitors shows a direct correlation between potency to inhibit LRRK2 kinase activity in vitro and potency to dephosphorylate LRRK2 at Ser935 in mammalian cell
2013 · Renée Vancraenenbroeck, Fangye Gao, et al.
Electron microscopy analysis of purified LRRK1 and LRRK2 demonstrates formation of dimers
2012 · Laura Civiero, Evy Lobbestael, et al. · F1000Research
Identification of protein phosphatase 1 as a regulator of the phosphorylation of LRRK2 in cells
2012 · Evy Lobbestael, Jane Zhao, et al.
Protein-protein interaction partner screening reveals EGF-R and 14-3-3 as specific interactors of LRRK1 and LRRK2, respectively
2012 · Lauran Reyniers, Laura Civiero, et al.
Protein array analysis reveals EGF-R and 14-3-3 as differential interactors of LRRK1 and LRRK2, respectively
2011 · Jean‐Marc Taymans, Laura Civiero, et al.
Identification of protein phosphatases that mediate the phosphorylation status of LRRK2 in cells
2011 · Evy Lobbestael, Fangye Gao, et al.
Leucine-rich repeat kinase 1 and 2: A biochemical comparison
2011 · Elisa Greggio, Laura Civiero, et al.
Regulation of LRRK2 kinase activity by GTP is indirect and requires upstream binding proteins
2010 · Jean‐Marc Taymans, Fangye Gao, et al.
Purification of recombinant leucine rich repeat kinase 2 and comparative analysis of its kinase and GTPase functions
2009 · Jean‐Marc Taymans, Fangye Gao, et al. · Lirias
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Works count: 24
Citation count: 812
H-index: 6
I10-index: 6
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