Get started
Author

Xiaoguang Pan

Observed names: X Pan, 潘晓光(Pan Xiaoguang)
ORCID: 0000-0002-2688-9245
Observed ORCID: 0000-0002-2688-9245
OpenAlex ID: A5060585393
Enhancing CRISPR-Cas9 gRNA efficiency prediction by data integration and deep learning
2021 · Xi Xiang, Giulia I. Corsi, et al. · Nature Communications · 208
PDF
CRISPR/Cas9 gRNA activity depends on free energy changes and on the target PAM context
2022 · Giulia I. Corsi, Kunli Qu, et al. · Nature Communications · 100
PDF
Circle‐Seq reveals genomic and disease‐specific hallmarks in urinary cell‐free extrachromosomal circular DNAs
2022 · Wei Lv, Xiaoguang Pan, et al. · Clinical and Translational Medicine · 85
Genome-wide characterization of extrachromosomal circular DNA in gastric cancer and its potential role in carcinogenesis and cancer progression
2023 · Xianming Jiang, Xiaoguang Pan, et al. · Cellular and Molecular Life Sciences · 51
PDF
Massively targeted evaluation of therapeutic CRISPR off-targets in cells
2022 · Xiaoguang Pan, Kunli Qu, et al. · Nature Communications · 42
PDF
Efficient correction of Duchenne muscular dystrophy mutations by SpCas9 and dual gRNAs
2021 · Xi Xiang, Xiaoying Zhao, et al. · Molecular Therapy — Nucleic Acids · 31
Extrachromosomal circular DNA orchestrates genome heterogeneity in urothelial bladder carcinoma
2024 · Wei Lv, Xiaoguang Pan, et al. · Theranostics · 28
PDF
Spatial–Temporal Diversity of Extrachromosomal DNA Shapes Urothelial Carcinoma Evolution and the Tumor Immune Microenvironment
2025 · Wei Lv, Yuchen Zeng, et al. · Cancer Discovery · 24
Characterization of Plasma Extrachromosomal Circular DNA in Gouty Arthritis
2022 · Jingyuan Pang, Xiaoguang Pan, et al. · Frontiers in Genetics · 24
PDF
Plasma extrachromosomal circular DNA is a pathophysiological hallmark of short‐term intensive insulin therapy for type 2 diabetes
2023 · Zhe Xu, Junyu He, et al. · Clinical and Translational Medicine · 23
PDF
Recent development of urinary biomarkers for bladder cancer diagnosis and monitoring
2023 · Yuchen Zeng, Anqi Wang, et al. · Clinical and Translational Discovery · 17
PDF
Haplotyping by CRISPR-mediated DNA circularization (CRISPR-hapC) broadens allele-specific gene editing
2019 · Jiaying Yu, Xi Xiang, et al. · Nucleic Acids Research · 15
PDF
Hyper-recombination in ribosomal DNA is driven by long-range resection-independent RAD51 accumulation
2024 · Zita Gál, Stavroula Boukoura, et al. · Nature Communications · 13
PDF
The single-cell expression profile of transposable elements and transcription factors in human early biparental and uniparental embryonic development
2022 · Conghui Li, Yue Zhang, et al. · Frontiers in Cell and Developmental Biology · 10
Identification of the transcriptome signatures and immune-inflammatory responses in postmenopausal osteoporosis
2023 · Pan Gao, Xiaoguang Pan, et al. · Heliyon · 9
Deep learning models simultaneously trained on multiple datasets improve base-editing activity prediction
2025 · Ying Sun, Kunli Qu, et al. · Nature Communications · 6
PDF
Identification and functional analysis of circulating extrachromosomal circular DNA in schizophrenia implicate its negative effect on the disorder
2023 · Xi Xiang, Xiaoguang Pan, et al. · Clinical and Translational Medicine · 6
PDF
LION: a simple and rapid method to achieve CRISPR gene editing
2019 · Xi Xiang, Lidan Luo, et al. · Cellular and Molecular Life Sciences · 5
Extrachromosomal circular miRNA-gene amplifications contribute to the renal cancer phenotype
2025 · Peng Han, Wei Lv, et al. · Cell Reports · 3
Massively Targeted Evaluation of Therapeutic CRISPR Off-Targets in Cells
2022 · Xiaoguang Pan, Kunli Qu, et al. · Research Square · 3
PDF
Massively parallel quantification of CRISPR editing in cells by TRAP-seq enables better design of Cas9, ABE, CBE gRNAs of high efficiency and accuracy
2020 · Xi Xiang, Kunli Qu, et al. · bioRxiv (Cold Spring Harbor Laboratory) · 3
PDF
Landscape of A-I RNA editing in mouse, pig, macaque, and human brains
2025 · Conghui Li, Wei Lv, et al. · Nucleic Acids Research · 2
PDF
Abstract 2668: Spatial-temporal diversity of extrachromosomal DNA shapes urothelial carcinoma evolution and tumor-immune microenvironment
2025 · Wei Lv, Yuchen Zeng, et al. · Cancer Research · 1
Cell free extrachromosomal circular DNA is common in human urine
2021 · Wei Lv, Xiaoguang Pan, et al. · bioRxiv (Cold Spring Harbor Laboratory) · 1
PDF
Endonuclease-Assisted Selective Exponential Amplification for Ultrasensitive Enrichment and Detection of Low-Abundance Mutant Alleles in Lung Cancer
2026 · Pei Li, Bao Lv, et al. · Journal of Molecular Diagnostics
Works count: 39
Citation count: 710
H-index: 13
I10-index: 14
Year
Topic
Type