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Nigel Beaton
Observed names:
Beaton, Nigel,
Beaton, Nigel Alexander,
N. Beaton
Institution:
Biognosys (Switzerland)
Observed institutions:
Heidelberg University,
The Royal Free Hospital,
ETH Zurich,
Biognosys (Switzerland),
Institute of Food, Nutrition, and Health,
University College London
show all 6
ORCID:
0000-0003-3852-0223
Observed ORCID:
0000-0003-3852-0223
OpenAlex ID:
A5060774960
A machine learning-based chemoproteomic approach to identify drug targets and binding sites in complex proteomes
2020
·
Ilaria Piazza
, Nigel Beaton
, et al.
·
Nature Communications
·
192
PDF
Regulation of Adipocyte Formation by GLP-1/GLP-1R Signaling
2011
·
Tenagne Delessa Challa
, Nigel Beaton
, et al.
·
Journal of Biological Chemistry
·
155
PDF
Proteome-wide structural changes measured with limited proteolysis-mass spectrometry: an advanced protocol for high-throughput applications
2022
·
Liliana Malinovska
, Valentina Cappelletti
, et al.
·
Nature Protocols
·
142
Adipogenesis and insulin sensitivity in obesity are regulated by retinoid‐related orphan receptor gamma
2011
·
Bettina Meissburger
, Jozef Ukropec
, et al.
·
EMBO Molecular Medicine
·
109
PDF
Compounds activating VCP D1 ATPase enhance both autophagic and proteasomal neurotoxic protein clearance
2022
·
Lidia Wrobel
, Sandra M. Hill
, et al.
·
Nature Communications
·
46
PDF
TUSC5 regulates insulin-mediated adipose tissue glucose uptake by modulation of GLUT4 recycling
2015
·
Nigel Beaton
, Carla Rudigier
, et al.
·
Molecular Metabolism
·
40
PDF
A haemocompatible and scalable nanoporous adsorbent monolith synthesised using a novel lignin binder route to augment the adsorption of poorly removed uraemic toxins in haemodialysis
2017
·
Susan R Sandeman
, Yishan Zheng
, et al.
·
Biomedical Materials
·
36
PDF
TaqIA polymorphism in dopamine D2 receptor gene complicates weight maintenance in younger obese patients
2012
·
Julia K. Winkler
, Annika Woehning
, et al.
·
Nutrition
·
34
Mechanistic Insights into a CDK9 Inhibitor Via Orthogonal Proteomics Methods
2021
·
J. Adam Hendricks
, Nigel Beaton
, et al.
·
ACS Chemical Biology
·
14
PDF
Bioinspired detoxification of blood: The efficient removal of anthrax toxin protective antigen using an extracorporeal macroporous adsorbent device
2018
·
Ganesh Ingavle
, Les Baillie
, et al.
·
Scientific Reports
·
10
PDF
Serum proteomics reveals survival-associated biomarkers in pancreatic cancer patients treated with chemoimmunotherapy
2025
·
Marco Tognetti
, Lopamudra Chatterjee
, et al.
·
iScience
·
8
Author Correction: Proteome-wide structural changes measured with limited proteolysis-mass spectrometry: an advanced protocol for high-throughput applications
2023
·
Liliana Malinovska
, Valentina Cappelletti
, et al.
·
Nature Protocols
·
3
PDF
602 Mass spectrometry-based protein biomarker analysis in chemoimmunotherapy combinations identifies unique immune signatures in pancreatic cancer
2022
·
Marco Tognetti
, Nigel Beaton
, et al.
·
Journal for ImmunoTherapy of Cancer
·
2
PDF
LiP-Quant, an automated chemoproteomic approach to identify drug targets in complex proteomes
2020
·
Y. Feng
, N. Beaton
, et al.
·
European Journal of Cancer
·
2
PDF
Abstract 2755: Limited proteolysis coupled to mass spectrometry (LiP-MS), a novel drug target deconvolution strategy
2019
·
Nigel Beaton
, Roland Bruderer
, et al.
·
Cancer Research
·
2
Abstract 5776: Target identification, selectivity profiling and binding site mapping of small molecule and peptide drugs by LiP-MS
2024
·
Fabio Sabino
, Martin Soste
, et al.
·
Cancer Research
·
1
Abstract 3847: Target identification of a multi-pass transmembrane G protein coupled receptor using limited-proteolysis coupled mass spectrometry (LiP-MS)
2023
·
Martin Soste
, Dominique Kamber
, et al.
·
Cancer Research
·
1
The Marine Product Elatol Is a Novel Inhibitor of Mitochondrial Translation Triggering the Integrated Stress Response and Apoptosis in Leukemia and Lymphoma Cells
2022
·
Tyler A. Cunningham
, Priyanka Maiti
, et al.
·
Blood
·
1
High-Resolution Limited Proteolysis (HR-LIP): A novel approach for target validation and lead compound optimization
2020
·
Y. Feng
, N. Beaton
, et al.
·
European Journal of Cancer
·
1
Abstract 6404: LiP-Quant, an automated chemoproteomic approach to identify drug targets in complex proteomes
2020
·
Yuehan Feng
, Nigel Beaton
, et al.
·
Cancer Research
·
1
Abstract C078: Pembrolizumab response in melanoma patients: an analysis of the tumor microenvironment
2023
·
Anna Juncker-Jensen
, Juliana Wortman
, et al.
·
Molecular Cancer Therapeutics
Abstract 5300: Mass spectrometry-based protein biomarker analysis in chemoimmunotherapy combinations identifies unique immune signatures in pancreatic cancer
2023
·
Nigel Beaton
, Marco Tognetti
, et al.
·
Cancer Research
Abstract 2024: High resolution limited proteolysis (HR-LiP), a novel structural proteomics approach for the prediction of small molecule-protein binding events
2023
·
Nigel Beaton
, Roland Bruderer
, et al.
·
Cancer Research
Abstract 1267: Dual approach using unbiased proteomics and multiplexed immunofluorescence for the detection of markers predictive for immunotherapy in melanoma patients
2022
·
Anna Juncker-Jensen
, Nigel Beaton
, et al.
·
Cancer Research
Abstract 3923: Ubiquitin ligases implicated as predictive biomarkers for poor outcome to immunotherapy in melanoma patients
2022
·
Nigel Beaton
, Tobias Treiber
, et al.
·
Cancer Research
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Works count:
34
Citation count:
800
H-index:
10
I10-index:
10
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