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Author

Yunoshin Tamura

ORCID: 0000-0003-3901-4082
Observed ORCID: 0000-0003-3901-4082
OpenAlex ID: A5061151303
Discovery of ORN0829, a potent dual orexin 1/2 receptor antagonist for the treatment of insomnia
2020 · Aya Futamura, Ryo Suzuki, et al. · Bioorganic & Medicinal Chemistry · 32
Binding Free-Energy Calculation Is a Powerful Tool for Drug Optimization: Calculation and Measurement of Binding Free Energy for 7-Azaindole Derivatives to Glycogen Synthase Kinase-3β
2014 · Kunihiro Kitamura, Yunoshin Tamura, et al. · Journal of Chemical Information and Modeling · 28
Discovery and optimization of a series of 2-aminothiazole-oxazoles as potent phosphoinositide 3-kinase γ inhibitors
2012 · Yusuke Oka, Tetsuya Yabuuchi, et al. · Bioorganic & Medicinal Chemistry Letters · 26
Discovery of TP0597850: A Selective, Chemically Stable, and Slow Tight-Binding Matrix Metalloproteinase-2 Inhibitor with a Phenylbenzamide–Pentapeptide Hybrid Scaffold
2023 · Tomoki Takeuchi, Yusaku Nomura, et al. · Journal of Medicinal Chemistry · 23
Lead optimization of 8-(methylamino)-2-oxo-1,2-dihydroquinolines as bacterial type II topoisomerase inhibitors
2020 · Fumihito Ushiyama, Hideaki Amada, et al. · Bioorganic & Medicinal Chemistry · 22
Unique structure of ozoralizumab, a trivalent anti-TNFα NANOBODY® compound, offers the potential advantage of mitigating the risk of immune complex-induced inflammation
2023 · Masanao Kyuuma, Ayaka Kaku, et al. · Frontiers in Immunology · 21
Design and Synthesis of 2-(1-Alkylaminoalkyl)pyrazolo[1,5-a]pyrimidines as New Respiratory Syncytial Virus Fusion Protein Inhibitors
2020 · Toru Yamaguchi-Sasaki, Yunoshin Tamura, et al. · Chemical and Pharmaceutical Bulletin · 15
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Discovery of novel indole derivatives as potent and selective inhibitors of proMMP-9 activation
2023 · Rie Nishikawa-Shimono, Motoi Kuwabara, et al. · Bioorganic & Medicinal Chemistry Letters · 13
Identification of highly selective and potent orexin receptor 1 antagonists derived from a dual orexin receptor 1/2 antagonist based on the structural framework of pyrazoylethylbenzamide
2017 · Aya Futamura, Dai Nozawa, et al. · Bioorganic & Medicinal Chemistry · 13
Discovery of Highly Potent and Selective Matrix Metalloproteinase-7 Inhibitors by Hybridizing the S1′ Subsite Binder with Short Peptides
2022 · Hideaki Tabuse, Kumi Abe-Sato, et al. · Journal of Medicinal Chemistry · 12
Molecular Dynamics Unveils Multiple-Site Binding of Inhibitors with Reduced Activity on the Surface of Dihydrofolate Reductase
2024 · Mitsugu Araki, Toru Ekimoto, et al. · Journal of the American Chemical Society · 8
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Binding interaction of SGLT with sugar and thiosugar by the molecular dynamics simulation
2015 · Yunoshin Tamura, Hiroh Miyagawa, et al. · Biochimica et Biophysica Acta (BBA) - Biomembranes · 8
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Thermoreversible gelation with hydrogen‐bonded zipper‐like crosslink junctions
2005 · Yunoshin Tamura, Fumihiko Tanaka · Journal of Polymer Science Part B Polymer Physics · 2
Works count: 13
Citation count: 223
H-index: 10
I10-index: 10
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