Author

Roshni V. Madhvani

Observed names: Roshni Madhvani, Roshni Vyas Madhvani

Institution: Cytokinetics (United States)

Observed institutions: University of California, Los Angeles, Stanford Medicine, Cytokinetics (United States), Stanford University

ORCID: 0000-0002-6876-5419

Observed ORCID: 0000-0002-6876-5419

OpenAlex ID: A5061168614

Aficamten is a small-molecule cardiac myosin inhibitor designed to treat hypertrophic cardiomyopathy

2024 · James J. Hartman, Darren T. Hwee, et al. · Nature Cardiovascular Research · 73

Shaping a new Ca 2+ conductance to suppress early afterdepolarizations in cardiac myocytes

2011 · Roshni V. Madhvani, Yuanfang Xie, et al. · The Journal of Physiology · 61

Targeting the late component of the cardiac L-type Ca2+ current to suppress early afterdepolarizations

2015 · Roshni V. Madhvani, Marina Angelini, et al. · The Journal of General Physiology · 47

Site-Directed Alkylation of Cysteine Replacements in the Lactose Permease of Escherichia coli : Helices I, III, VI, and XI

2006 · Natalia Ermolova, Roshni Vyas Madhvani, et al. · Biochemistry · 23

Stochastic pacing reveals the propensity to cardiac action potential alternans and uncovers its underlying dynamics

2015 · Yann Prudat, Roshni V. Madhvani, et al. · The Journal of Physiology · 19

Wnt Signaling Interactor WTIP (Wilms Tumor Interacting Protein) Underlies Novel Mechanism for Cardiac Hypertrophy

2022 · Hannah N. De Jong, Frederick E. Dewey, et al. · Circulation Genomic and Precision Medicine · 3

The Cytochrome C-Like Domain of the Human BK Channel

2014 · Taleh Yusifov, Roshni V. Madhvani, et al. · Biophysical Journal · 2

Preclinical characterization of CK-4021586, a new class of cardiac myosin inhibitors for the treatment of hypertrophic cardiomyopathy

2023 · Saswata Sankar Sarkar, James J. Hartman, et al. · Biophysical Journal · 1

Suppressing Early Afterdepolarizations in Cardiac Myocytes by Shaping a Modified Ca2+ Conductance Under Dynamic Clamp

2011 · Roshni V. Madhvani, Yuanfang Xie, et al. · Biophysical Journal · 1

L-type Ca2+ channels as therapeutic targets for Early afterdepolarization-related arrhythmias

2014 · Roshni V. Madhvani · eScholarship (California Digital Library)

Tuning L-Type Ca2+ Current Properties to Suppress Early After depolarizations

2013 · Roshni V. Madhvani, Yuanfang Xie, et al. · Biophysical Journal

How do L-Type Calcium Current Kinetics Contribute to Early After Depolarizations in Cardiac Myocytes?

2012 · Roshni V. Madhvani, Yuanfang Xie, et al. · Biophysical Journal

Biophysical Characterization of Iks Channels in Cardiomyocytes Derived from Human Embryonic Stem Cells Reveals Insights Into Stoichiometry of KCNQ1-KCNE1 Complex

2011 · Roshni V. Madhvani, Yuanfang Xie, et al.

Works count: 13

Citation count: 230

H-index: 5

I10-index: 5