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Neil R. Stokes

Protection of Escherichia coli cells against extreme turgor by activation of MscS and MscL mechanosensitive channels: identification of genes required for MscS activity
1999 · Natalia Levina, Sabine Tötemeyer, et al. · The EMBO Journal · 725
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An Inhibitor of FtsZ with Potent and Selective Anti-Staphylococcal Activity
2008 · David J. Haydon, Neil R. Stokes, et al. · Science · 459
Characterization of three novel mechanosensitive channel activities inEscherichia coli
2012 · Michelle D. Edwards, Susan Black, et al. · Channels · 139
Novel Inhibitors of Bacterial Cytokinesis Identified by a Cell-based Antibiotic Screening Assay
2005 · Neil R. Stokes, Jörg Sievers, et al. · Journal of Biological Chemistry · 111
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A role for mechanosensitive channels in survival of stationary phase: Regulation of channel expression by RpoS
2003 · Neil R. Stokes, Heath D. Murray, et al. · Proceedings of the National Academy of Sciences · 111
Creating an Antibacterial with in Vivo Efficacy: Synthesis and Characterization of Potent Inhibitors of the Bacterial Cell Division Protein FtsZ with Improved Pharmaceutical Properties
2010 · David J. Haydon, James M. Bennett, et al. · Journal of Medicinal Chemistry · 109
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An Improved Small-Molecule Inhibitor of FtsZ with Superior In Vitro Potency, Drug-Like Properties, and In Vivo Efficacy
2012 · Neil R. Stokes, Nicola Baker, et al. · Antimicrobial Agents and Chemotherapy · 96
Antibacterial alkoxybenzamide inhibitors of the essential bacterial cell division protein FtsZ
2008 · Lloyd G. Czaplewski, Ian Collins, et al. · Bioorganic & Medicinal Chemistry Letters · 91
Design, synthesis and structure–activity relationships of substituted oxazole–benzamide antibacterial inhibitors of FtsZ
2013 · Neil R. Stokes, Nicola Baker, et al. · Bioorganic & Medicinal Chemistry Letters · 82
Novel Bacterial Topoisomerase Inhibitors with Potent Broad-Spectrum Activity against Drug-Resistant Bacteria
2017 · Cédric Charrier, Anne-Marie Salisbury, et al. · Antimicrobial Agents and Chemotherapy · 46
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Design, synthesis and biological evaluation of α-substituted isonipecotic acid benzothiazole analogues as potent bacterial type II topoisomerase inhibitors
2013 · Lorraine C. Axford, Piyush K. Agarwal, et al. · Bioorganic & Medicinal Chemistry Letters · 39
Biological Evaluation of Benzothiazole Ethyl Urea Inhibitors of Bacterial Type II Topoisomerases
2013 · Neil R. Stokes, Helena B. Thomaides-Brears, et al. · Antimicrobial Agents and Chemotherapy · 34
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Biological profiling of novel tricyclic inhibitors of bacterial DNA gyrase and topoisomerase IV
2016 · Victoria J. Savage, Cédric Charrier, et al. · Journal of Antimicrobial Chemotherapy · 28
Discovery and in vivo evaluation of alcohol-containing benzothiazoles as potent dual-targeting bacterial DNA supercoiling inhibitors
2014 · James T. Palmer, Lorraine C. Axford, et al. · Bioorganic & Medicinal Chemistry Letters · 21
Transcriptional Responses of Intestinal Epithelial Cells to Infection with Vibrio cholerae
2004 · Neil R. Stokes, Xin Zhou, et al. · Infection and Immunity · 21
Design, synthesis and antibacterial properties of pyrimido[4,5-b]indol-8-amine inhibitors of DNA gyrase
2018 · David H. McGarry, Ian R. Cooper, et al. · Bioorganic & Medicinal Chemistry Letters · 18
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Discovery and structure–activity relationships of a novel oxazolidinone class of bacterial type II topoisomerase inhibitors
2022 · Amanda Lyons, James Kirkham, et al. · Bioorganic & Medicinal Chemistry Letters · 16
Discovery and structure–activity relationships of a novel isothiazolone class of bacterial type II topoisomerase inhibitors
2016 · Ian R. Cooper, Andrew J. McCarroll, et al. · Bioorganic & Medicinal Chemistry Letters · 11
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Efficacy of a Novel Tricyclic Topoisomerase Inhibitor in a Murine Model of Neisseria gonorrhoeae Infection
2016 · Victoria J. Savage, Cédric Charrier, et al. · Antimicrobial Agents and Chemotherapy · 10
In vitrobiological evaluation of novel broad-spectrum isothiazolone inhibitors of bacterial type II topoisomerases
2016 · Cédric Charrier, Anne-Marie Salisbury, et al. · Journal of Antimicrobial Chemotherapy · 9
STING Agonist Induced Innate Immune Responses Drive Anti-Respiratory Virus Activity In Vitro with Limited Antiviral Efficacy In Vivo
2024 · Rebecca Broeckel, Amanda Browne, et al. · ACS Infectious Diseases · 7
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Discovery of Potent STT3A/B Inhibitors and Assessment of Their Multipathogen Antiviral Potential and Safety
2024 · Joseph E. Pero, Elizabeth A. Mueller, et al. · Journal of Medicinal Chemistry · 7
Rational design, synthesis and testing of novel tricyclic topoisomerase inhibitors for the treatment of bacterial infections part 1
2020 · R. Kirk, A. Ratcliffe, et al. · RSC Medicinal Chemistry · 5
Antibacterial Inhibitors of the Essential Cell Division Protein FtsZ
2011 · Lloyd G. Czaplewski, Neil R. Stokes, et al. · Springer eBooks · 5
Rational design, synthesis and testing of novel tricyclic topoisomerase inhibitors for the treatment of bacterial infections part 2
2020 · R. Kirk, A. Ratcliffe, et al. · RSC Medicinal Chemistry · 2
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Works count: 27
Citation count: 2,203
H-index: 16
I10-index: 19
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