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Wells S. Brown
Observed names:
Wells Brown,
Wells S Brown
Institution:
BC Cancer Agency
Observed institutions:
BC Cancer Agency,
The University of Texas MD Anderson Cancer Center,
University of British Columbia,
Baylor College of Medicine,
Purdue University West Lafayette,
National Taiwan University Hospital,
Purdue University Institute for Cancer Research,
Taipei Medical University
show all 8
ORCID:
0000-0002-6979-9143
Observed ORCID:
0000-0002-6979-9143
OpenAlex ID:
A5061255878
Regulation of pH by Carbonic Anhydrase 9 Mediates Survival of Pancreatic Cancer Cells With Activated KRAS in Response to Hypoxia
2019
·
Paul C. McDonald
, Shawn C. Chafe
, et al.
·
Gastroenterology
·
224
PDF
Genome-wide synthetic lethal screen unveils novel CAIX-NFS1/xCT axis as a targetable vulnerability in hypoxic solid tumors
2021
·
Shawn C. Chafe
, Frederick S. Vizeacoumar
, et al.
·
Science Advances
·
140
PDF
Spleen Tyrosine Kinase–Mediated Autophagy Is Required for Epithelial–Mesenchymal Plasticity and Metastasis in Breast Cancer
2019
·
Aparna Shinde
, Shana D. Hardy
, et al.
·
Cancer Research
·
115
Overcoming Adaptive Resistance to KRAS and MEK Inhibitors by Co-targeting mTORC1/2 Complexes in Pancreatic Cancer
2020
·
Wells S. Brown
, Paul C. McDonald
, et al.
·
Cell Reports Medicine
·
111
PDF
Targeting Constitutively Activated β1 Integrins Inhibits Prostate Cancer Metastasis
2013
·
Yu-Chen Lee
, Jung-Kang Jin
, et al.
·
Molecular Cancer Research
·
89
The PI3-Kinase Delta Inhibitor Idelalisib (GS-1101) Targets Integrin-Mediated Adhesion of Chronic Lymphocytic Leukemia (CLL) Cell to Endothelial and Marrow Stromal Cells
2013
·
Stefania Fiorcari
, Wells S. Brown
, et al.
·
PLoS ONE
·
87
PDF
Covalent Targeting of Fibroblast Growth Factor Receptor Inhibits Metastatic Breast Cancer
2016
·
Wells S. Brown
, Li Tan
, et al.
·
Molecular Cancer Therapeutics
·
77
FGFR signaling maintains a drug persistent cell population following epithelial-mesenchymal transition
2016
·
Wells S. Brown
, Saeed Salehin Akhand
, et al.
·
Oncotarget
·
56
PDF
Epigenetic targeting of neuropilin-1 prevents bypass signaling in drug-resistant breast cancer
2020
·
Ammara Abdullah
, Saeed Salehin Akhand
, et al.
·
Oncogene
·
40
PDF
Clustering T‐cell GM1 lipid rafts increases cellular resistance to shear on fibronectin through changes in integrin affinity and cytoskeletal dynamics
2009
·
Jason S Mitchell
, Wells S Brown
, et al.
·
Immunology and Cell Biology
·
36
Small Molecule Agonist of Very Late Antigen-4 (VLA-4) Integrin Induces Progenitor Cell Adhesion
2013
·
Peter Vanderslice
, Ronald J. Biediger
, et al.
·
Journal of Biological Chemistry
·
32
PDF
A Carbonic Anhydrase IX/SLC1A5 Axis Regulates Glutamine Metabolism Dependent Ferroptosis in Hypoxic Tumor Cells
2022
·
Geetha Venkateswaran
, Paul C. McDonald
, et al.
·
Molecular Cancer Therapeutics
·
31
PDF
Biased signaling downstream of epidermal growth factor receptor regulates proliferative versus apoptotic response to ligand
2018
·
Remah Ali
, Wells Brown
, et al.
·
Cell Death and Disease
·
29
PDF
Neutrophil extracellular trap gene expression signatures identify prognostic and targetable signaling axes for inhibiting pancreatic tumour metastasis
2025
·
Paul C. McDonald
, James T. Topham
, et al.
·
Communications Biology
·
18
B-Raf Regulation of Integrin α4β1-mediated Resistance to Shear Stress through Changes in Cell Spreading and Cytoskeletal Association in T Cells
2014
·
Wells S. Brown
, Jahan S. Khalili
, et al.
·
Journal of Biological Chemistry
·
14
PDF
Synthesis and Evaluation of an Anti-MLC1 × Anti-CD90 Bispecific Antibody for Targeting and Retaining Bone-Marrow-Derived Multipotent Stromal Cells in Infarcted Myocardium
2011
·
C. William Gundlach IV
, Amy Caivano
, et al.
·
Bioconjugate Chemistry
·
14
Selective Inhibition of STAT3 Phosphorylation Using a Nuclear-Targeted Kinase Inhibitor
2017
·
Matthew D. Bartolowits
, Wells Brown
, et al.
·
ACS Chemical Biology
·
13
2E8 Binds to the High Affinity I-domain in a Metal Ion-dependent Manner
2010
·
Roberto Carreño
, Wells S. Brown
, et al.
·
Journal of Biological Chemistry
·
8
Integrin-mediated resistance to epidermal growth factor receptor-targeted therapy: an inflammatory situation
2014
·
Wells S Brown
, Michael K Wendt
·
Breast Cancer Research
·
6
PDF
Abstract 6002: Increased ferroptosis sensitivity and epithelial to mesenchymal transition of breast cancer cells overcoming chemotherapeutic mediated apoptotic caspase activation
2024
·
Rachel Hausman
, Wells Brown
, et al.
·
Cancer Research
·
3
Correction: Epigenetic targeting of neuropilin-1 prevents bypass signaling in drug-resistant breast cancer
2023
·
Ammara Abdullah
, Saeed Salehin Akhand
, et al.
·
Oncogene
·
3
PDF
The PI3 Kinase δ Inhibitor, CAL-101 (GS-1101), Inhibits Chronic Lymphocytic Leukemia (CLL) Cell Survival in Endothelial and Marrow Stromal Cell Co-Cultures.
2011
·
Stefania Fiorcari
, Wells S Brown
, et al.
·
Blood
·
3
Abstract 5997: The role of neutrophil extracellular trap-CCDC25-integrin linked kinase complex in pancreatic cancer progression and metastasis
2022
·
Paul C. McDonald
, Wells S. Brown
, et al.
·
Cancer Research
·
1
Survival of cancer cells following taxol-induced apoptosis is supported by ZEB1-mediated ferroptosis sensitivity
2026
·
Rachel Hausman
, Wells S. Brown
, et al.
·
Cell Death and Disease
PDF
Abstract 4659: Survival of TNBC cells following taxol induced apoptotic caspase activation (anastasis) depends on enhanced ferroptosis sensitivity
2026
·
Rachel Hausman
, Wells Brown
, et al.
·
Cancer Research
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Works count:
72
Citation count:
1,150
H-index:
14
I10-index:
17
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