Get started
Author

Penny A. Handford

Observed names: Handford, Penny, Handford, Penny A, Handford, Penny A., P A Handford, P Handford, P. A. HANDFORD, P. A. Handford, P. Handford, P.A Handford, P.A. Handford, Penny A Handford, Penny Ann Handford, Penny Handford, Penny A. Handford
ORCID: 0000-0002-0590-7651
Observed ORCID: 0000-0002-0590-7651
OpenAlex ID: A5061413790
Somatic mutant clones colonize the human esophagus with age
2018 · Iñigo Martincorena, Joanna C. Fowler, et al. · Science · 1,115
Solution Structure of a Pair of Calcium-Binding Epidermal Growth Factor-like Domains: Implications for the Marfan Syndrome and Other Genetic Disorders
1996 · A.K Downing, V Knott, et al. · Cell · 446
PDF
The molecular genetics of Marfan syndrome and related disorders
2006 · P N Robinson, E Arteaga-Solis, et al. · Journal of Medical Genetics · 430
PDF
The structure of a Ca2+-binding epidermal growth factor-like domain: Its role in protein-protein interactions
1995 · Zihe Rao, Penny Handford, et al. · Cell · 344
PDF
Key residues involved in calcium-binding motifs in EGF-like domains
1991 · P. A. Handford, M. Mayhew, et al. · Nature · 283
A conserved face of the Jagged/Serrate DSL domain is involved in Notch trans-activation and cis-inhibition
2008 · Jemima Cordle, Steven Johnson, et al. · Nature Structural & Molecular Biology · 265
Mutations in Fibrillin-1 Cause Congenital Scleroderma: Stiff Skin Syndrome
2010 · B. L. Loeys, E. E. Gerber, et al. · Science Translational Medicine · 239
The role of beta‐hydroxyaspartate and adjacent carboxylate residues in the first EGF domain of human factor IX.
1988 · D. J. Rees, I. M. Jones, et al. · The EMBO Journal · 238
Mutations in the TGFβ Binding-Protein-Like Domain 5 of FBN1 Are Responsible for Acromicric and Geleophysic Dysplasias
2011 · Carine Le Goff, Clémentine Mahaut, et al. · The American Journal of Human Genetics · 229
PDF
Notch receptor–ligand binding and activation: Insights from molecular studies
2012 · Chandramouli R. Chillakuri, Devon Sheppard, et al. · Seminars in Cell and Developmental Biology · 214
PDF
The CD46-Jagged1 interaction is critical for human TH1 immunity
2012 · Gaëlle Le Friec, Devon Sheppard, et al. · Nature Immunology · 204
The first EGF‐like domain from human factor IX contains a high‐affinity calcium binding site.
1990 · P.A. Handford, M. Baron, et al. · The EMBO Journal · 191
CRB1 mutation spectrum in inherited retinal dystrophies
2004 · Anneke I. den Hollander, Jason Davis, et al. · Human Mutation · 188
PDF
Microfibrils, elastin fibres and collagen fibres in the human intervertebral disc and bovine tail disc
2007 · Jing Yu, Uday Tirlapur, et al. · Journal of Anatomy · 168
PDF
Structure of the Integrin Binding Fragment from Fibrillin-1 Gives New Insights into Microfibril Organization
2004 · Stephen S.J Lee, Vroni Knott, et al. · Structure · 133
PDF
Fibrillin: from domain structure to supramolecular assembly
2000 · P.A Handford, A.K Downing, et al. · Matrix Biology · 119
Calcium Binding Properties of an Epidermal Growth Factor-like Domain Pair from Human Fibrillin-1
1996 · Vroni Knott, Kristina A. Downing, et al. · Journal of Molecular Biology · 117
Fringe-mediated extension of O -linked fucose in the ligand-binding region of Notch1 increases binding to mammalian Notch ligands
2014 · Paul Taylor, Hideyuki Takeuchi, et al. · Proceedings of the National Academy of Sciences · 115
Molecular Analysis of the Epidermal Growth Factor-like Short Consensus Repeat Domain-mediated Protein-Protein Interactions
2001 · Hsi-Hsien Lin, Martin Stacey, et al. · Journal of Biological Chemistry · 115
PDF
Dissecting the Fibrillin Microfibril: Structural Insights into Organization and Function
2012 · Sacha A. Jensen, Ian B. Robertson, et al. · Structure · 114
PDF
Structural and Functional Properties of the Human Notch-1 Ligand Binding Region
2004 · Sophie Hambleton, Najl V. Valeyev, et al. · Structure · 107
PDF
Localization of the Delta-like-1-binding Site in Human Notch-1 and Its Modulation by Calcium Affinity
2008 · Jemima Cordle, Christina RedfieldZ, et al. · Journal of Biological Chemistry · 106
The Calcium Binding Properties and Molecular Organization of Epidermal Growth Factor-like Domains in Human Fibrillin-1
1995 · Penny Handford, A.Kristina Downing, et al. · Journal of Biological Chemistry · 102
TB domain proteins: evolutionary insights into the multifaceted roles of fibrillins and LTBPs
2010 · Ian Robertson, Sacha Jensen, et al. · Biochemical Journal · 101
Fibrillin-1, a calcium binding protein of extracellular matrix
2000 · P.A Handford · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · 95
PDF
Works count: 145
Citation count: 7,999
H-index: 45
I10-index: 78
Year
Topic
Type