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Laurent Gauthier

Anti-NKG2A mAb Is a Checkpoint Inhibitor that Promotes Anti-tumor Immunity by Unleashing Both T and NK Cells
2018 · Pascale André, Caroline Denis, et al. · Cell · 1,263
Identification, activation, and selective in vivo ablation of mouse NK cells via NKp46
2007 · Thierry Walzer, Mathieu Bléry, et al. · Proceedings of the National Academy of Sciences · 496
Multifunctional Natural Killer Cell Engagers Targeting NKp46 Trigger Protective Tumor Immunity
2019 · Laurent Gauthier, Ariane Morel, et al. · Cell · 454
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Blocking Antibodies Targeting the CD39/CD73 Immunosuppressive Pathway Unleash Immune Responses in Combination Cancer Therapies
2019 · Ivan Perrot, Henri-Alexandre Michaud, et al. · Cell Reports · 445
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Preclinical characterization of 1-7F9, a novel human anti–KIR receptor therapeutic antibody that augments natural killer–mediated killing of tumor cells
2009 · Francois Romagné, Pascale André, et al. · Blood · 430
Transglutaminase-Based Chemo-Enzymatic Conjugation Approach Yields Homogeneous Antibody–Drug Conjugates
2014 · Patrick Dennler, Aristeidis Chiotellis, et al. · Bioconjugate Chemistry · 306
Crystal Structure of HLA-DR2 (DRA*0101, DRB1*1501) Complexed with a Peptide from Human Myelin Basic Protein
1998 · Kathrine J. Smith, Jason Pyrdol, et al. · The Journal of Experimental Medicine · 300
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Ex vivo analysis of human memory CD4 T cells specific for hepatitis C virus using MHC class II tetramers
2003 · Cheryl L. Day, Nilufer P. Seth, et al. · Journal of Clinical Investigation · 294
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New immune cell engagers for cancer immunotherapy
2024 · Aurore Fenis, Olivier Demaria, et al. · Nature reviews. Immunology · 225
Natural killer cell engagers in cancer immunotherapy: Next generation of immuno‐oncology treatments
2021 · Olivier Demaria, Laurent Gauthier, et al. · European Journal of Immunology · 154
Complement factor P is a ligand for the natural killer cell–activating receptor NKp46
2017 · Emilie Narni-Mancinelli, Laurent Gauthier, et al. · Science Immunology · 144
Control of acute myeloid leukemia by a trifunctional NKp46-CD16a-NK cell engager targeting CD123
2023 · Laurent Gauthier, Angela Virone-Oddos, et al. · Nature Biotechnology · 116
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TLR3 and Rig-Like Receptor on Myeloid Dendritic Cells and Rig-Like Receptor on Human NK Cells Are Both Mandatory for Production of IFN-γ in Response to Double-Stranded RNA
2010 · Ivan Perrot, Florence Deauvieau, et al. · The Journal of Immunology · 115
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Site-Specific Conjugation of Monomethyl Auristatin E to Anti-CD30 Antibodies Improves Their Pharmacokinetics and Therapeutic Index in Rodent Models
2015 · F. Lhospice, D. Brégeon, et al. · Molecular Pharmaceutics · 114
Recombinant Soluble Human α3β1Integrin: Purification, Processing, Regulation, and Specific Binding to Laminin-5 and Invasin in a Mutually Exclusive Manner
1998 · Johannes A. Eble, Kai W. Wucherpfennig, et al. · Biochemistry · 109
IPH4102, a Humanized KIR3DL2 Antibody with Potent Activity against Cutaneous T-cell Lymphoma
2014 · Anne Marie-Cardine, Nicolas Viaud, et al. · Cancer Research · 89
Antitumor immunity induced by antibody-based natural killer cell engager therapeutics armed with not-alpha IL-2 variant
2022 · Olivier Demaria, Laurent Gauthier, et al. · Cell Reports Medicine · 80
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Structural Features of Autoreactive TCR That Determine the Degree of Degeneracy in Peptide Recognition
1999 · Stefan Hausmann, Margarita Martin, et al. · The Journal of Immunology · 70
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Kinetics of T-cell Receptor Binding by Bivalent HLA-DR·Peptide Complexes That Activate Antigen-specific Human T-cells
2000 · Heiner Appel, Laurent Gauthier, et al. · Journal of Biological Chemistry · 67
Binding of conserved islet peptides by human and murine MHC class II molecules associated with susceptibility to type I diabetes
2000 · Bei Yu, Laurent Gauthier, et al. · European Journal of Immunology · 60
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Binding Motifs of Copolymer 1 to Multiple Sclerosis- and Rheumatoid Arthritis-Associated HLA-DR Molecules
1999 · Masha Fridkis-Hareli, John M Neveu, et al. · The Journal of Immunology · 57
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Anergy Induction by Dimeric TCR Ligands
2001 · Heiner Appel, Nilufer P Seth, et al. · The Journal of Immunology · 53
Cutting Edge: Characterization of Allorestricted and Peptide-Selective Alloreactive T Cells Using HLA-Tetramer Selection
2001 · Arnaud Moris, Volker Teichgräber, et al. · The Journal of Immunology · 46
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Diverse expansion potential and heterogeneous avidity in tumor-associated antigen-specific T lymphocytes from primary melanoma patients
2001 · Belinda Palermo, Rita Campanelli, et al. · European Journal of Immunology · 44
Exploiting Natural Killer Cell Engagers to Control Pediatric B-cell Precursor Acute Lymphoblastic Leukemia
2022 · Natalia Colomar-Carando, Laurent Gauthier, et al. · Cancer Immunology Research · 43
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Works count: 64
Citation count: 5,837
H-index: 27
I10-index: 36
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