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Simon Linder

An androgen receptor switch underlies lineage infidelity in treatment-resistant prostate cancer
2021 · Alastair Davies, Shaghayegh Nouruzi, et al. · Nature Cell Biology · 172
Drug-Induced Epigenomic Plasticity Reprograms Circadian Rhythm Regulation to Drive Prostate Cancer toward Androgen Independence
2022 · Simon Linder, Marlous Hoogstraat, et al. · Cancer Discovery · 83
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Enzalutamide therapy for advanced prostate cancer: efficacy, resistance and beyond
2018 · Simon Linder, Henk G van der Poel, et al. · Endocrine Related Cancer · 78
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Genetic determinants of chromatin reveal prostate cancer risk mediated by context-dependent gene regulation
2022 · Sylvan C. Baca, Cassandra Singler, et al. · Nature Genetics · 61
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Androgen Receptor Inhibition Increases MHC Class I Expression and Improves Immune Response in Prostate Cancer
2024 · Lisa N. Chesner, Fanny Polesso, et al. · Cancer Discovery · 60
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Optimized ChIP-seq method facilitates transcription factor profiling in human tumors
2018 · Abhishek A Singh, Karianne Schuurman, et al. · Life Science Alliance · 55
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Mps1 inhibitors synergise with low doses of taxanes in promoting tumour cell death by enhancement of errors in cell division
2018 · Ana Rita R. Maia, Simon Linder, et al. · British Journal of Cancer · 53
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Dual functions of SPOP and ERG dictate androgen therapy responses in prostate cancer
2021 · Tiziano Bernasocchi, Geniver El Tekle, et al. · Nature Communications · 49
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Transposable Elements Are Co-opted as Oncogenic Regulatory Elements by Lineage-Specific Transcription Factors in Prostate Cancer
2023 · Giacomo Grillo, Tina Keshavarzian, et al. · Cancer Discovery · 41
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Molecular underpinnings of enzalutamide resistance
2018 · S Prekovic, T Van den Broeck, et al. · Endocrine Related Cancer · 37
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Functional mapping of androgen receptor enhancer activity
2021 · Chia-Chi Flora Huang, Shreyas Lingadahalli, et al. · Genome biology · 36
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Reduced NCOR2 expression accelerates androgen deprivation therapy failure in prostate cancer
2021 · Mark D. Long, Justine J. Jacobi, et al. · Cell Reports · 35
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Comparative transcriptomics reveals a mixed basal, club, and hillock epithelial cell identity in castration-resistant prostate cancer
2025 · Samuel P. Pitzen, Amber N. Rudenick, et al. · Proceedings of the National Academy of Sciences · 27
Zincore, an atypical coregulator, binds zinc finger transcription factors to control gene expression
2025 · Daniëlle Bianchi, Razvan Borza, et al. · Science · 22
Radiogenomics Analysis Linking Multiparametric MRI and Transcriptomics in Prostate Cancer
2023 · Catarina Dinis Fernandes, Annekoos Schaap, et al. · Cancers · 21
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A kinome-centered CRISPR-Cas9 screen identifies activated BRAF to modulate enzalutamide resistance with potential therapeutic implications in BRAF-mutated prostate cancer
2021 · Sander A. L. Palit, Jeroen van Dorp, et al. · Scientific Reports · 18
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Androgen modulation of XBP1 is functionally driving part of the AR transcriptional program
2019 · Suzan Stelloo, Simon Linder, et al. · Endocrine Related Cancer · 15
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Epigenetic profiling identifies markers of endocrine resistance and therapeutic options for metastatic castration-resistant prostate cancer
2025 · Tesa M. Severson, Emma Minnee, et al. · Cell Reports Medicine · 13
Compartmentalization of androgen receptors at endogenous genes in living cells
2023 · Selçuk Yavuz, Hélène Kabbech, et al. · Nucleic Acids Research · 10
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Unexpected gene activation following CRISPR‐Cas9‐mediated genome editing
2021 · Anna G Manjón, Simon Linder, et al. · EMBO Reports · 10
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Grade Group 1 Prostate Cancers Exhibit Tumor-defining Androgen Receptor–driven Programs
2023 · Simon Linder, Tesa M. Severson, et al. · European Urology · 9
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Low tristetraprolin expression activates phenotypic plasticity and primes transition to lethal prostate cancer in mice
2024 · Katherine L. Morel, Beatriz Germán, et al. · Journal of Clinical Investigation · 8
The unintended consequences of regulatory import: the Basel Accord’s failure during the financial crisis
2020 · Manuel Becker, Simon Linder · Journal of European Public Policy · 8
Selective targeting of TBXT with DARPins identifies regulatory networks and therapeutic vulnerabilities in chordoma
2025 · Charles S. Umbaugh, Marie Groth, et al. · Science Advances · 5
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TRIM33 loss reduces androgen receptor transcriptional output and H2BK120 ubiquitination
2025 · Nils Eickhoff, Janina Janetzko, et al. · Communications Biology · 4
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Works count: 94
Citation count: 937
H-index: 16
I10-index: 20
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