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Richard Vargas
Observed name:
Vargas, Richard
Observed institutions:
Pfizer (United States),
Blueprint Medicines (United States),
Wyeth
OpenAlex ID:
A5061596482
Discovery of Clinical Candidate 1-{[(2 S ,3 S ,4 S )-3-Ethyl-4-fluoro-5-oxopyrrolidin-2-yl]methoxy}-7-methoxyisoquinoline-6-carboxamide (PF-06650833), a Potent, Selective Inhibitor of Interleukin-1 Receptor Associated Kinase 4 (IRAK4), by Fragment-Based Drug Design
2017
·
Katherine L. Lee
, Catherine M. Ambler
, et al.
·
Journal of Medicinal Chemistry
·
152
Benzenesulfonamide indole inhibitors of cytosolic phospholipase A2α: Optimization of in vitro potency and rat pharmacokinetics for oral efficacy
2007
·
Katherine L. Lee
, Mark L. Behnke
, et al.
·
Bioorganic & Medicinal Chemistry
·
28
Efficacy and Safety of Remdesivir in People With Impaired Kidney Function Hospitalized for COVID-19 Pneumonia: A Randomized Clinical Trial
2024
·
Meghan E Sise
, Jose Ramon Santos
, et al.
·
Clinical Infectious Diseases
·
21
Abstract 2306: BLU-222, an investigational, potent, and selective CDK2 inhibitor, demonstrated robust antitumor activity in CCNE1-amplified ovarian cancer models
2022
·
Victoria Brown
, Phil Ramsden
, et al.
·
Cancer Research
·
14
Abstract 1279: Development of a selective CDK2-E inhibitor in CCNE driven cancers
2021
·
Yoon J. Choi
, Steve Wenglowsky
, et al.
·
Cancer Research
·
7
CCDC 1566948: Experimental Crystal Structure Determination
2017
·
Lee, Katherine L.
, Ambler, Catherine M.
, et al.
·
The Cambridge Structural Database
CCDC 1566946: Experimental Crystal Structure Determination
2017
·
Lee, Katherine L.
, Ambler, Catherine M.
, et al.
·
The Cambridge Structural Database
CCDC 1566947: Experimental Crystal Structure Determination
2017
·
Lee, Katherine L.
, Ambler, Catherine M.
, et al.
·
The Cambridge Structural Database
CCDC 1566949: Experimental Crystal Structure Determination
2017
·
Lee, Katherine L.
, Ambler, Catherine M.
, et al.
·
The Cambridge Structural Database
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Works count:
9
Citation count:
221
H-index:
5
I10-index:
4
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