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Yann Kieffer

Fibroblast Heterogeneity and Immunosuppressive Environment in Human Breast Cancer
2018 · Ana Costa, Yann Kieffer, et al. · Cancer Cell · 1,734
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Single-Cell Analysis Reveals Fibroblast Clusters Linked to Immunotherapy Resistance in Cancer
2020 · Yann Kieffer, Hocine R. Hocine, et al. · Cancer Discovery · 941
Cancer-associated fibroblast heterogeneity in axillary lymph nodes drives metastases in breast cancer through complementary mechanisms
2020 · Floriane Pelon, Brigitte Bourachot, et al. · Nature Communications · 401
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PML-Regulated Mitochondrial Metabolism Enhances Chemosensitivity in Human Ovarian Cancers
2018 · Géraldine Gentric, Yann Kieffer, et al. · Cell Metabolism · 317
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Lipid-Associated Macrophages Are Induced by Cancer-Associated Fibroblasts and Mediate Immune Suppression in Breast Cancer
2022 · Eleonora Timperi, Paul Gueguen, et al. · Cancer Research · 314
miR200-regulated CXCL12β promotes fibroblast heterogeneity and immunosuppression in ovarian cancers
2018 · Anne-Marie Givel, Yann Kieffer, et al. · Nature Communications · 307
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Dissection of intercellular communication using the transcriptome-based framework ICELLNET
2021 · Floriane Noël, Lucile Massenet-Regad, et al. · Nature Communications · 217
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Inhibition of autophagy as a new means of improving chemotherapy efficiency in high-LC3B triple-negative breast cancers
2014 · Sylvain Lefort, Carine Joffre, et al. · Autophagy · 191
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Chronic oxidative stress promotes H2AX protein degradation and enhances chemosensitivity in breast cancer patients
2016 · Tina Gruosso, Virginie Mieulet, et al. · EMBO Molecular Medicine · 182
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Deciphering the spatial landscape and plasticity of immunosuppressive fibroblasts in breast cancer
2024 · Hugo Croizer, Rana Mhaidly, et al. · Nature Communications · 181
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CXCR4 inhibitors could benefit to HER2 but not to triple-negative breast cancer patients
2016 · S Lefort, A Thuleau, et al. · Oncogene · 89
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Stiffness increases with myofibroblast content and collagen density in mesenchymal high grade serous ovarian cancer
2021 · Virginie Mieulet, Camille Garnier, et al. · Scientific Reports · 82
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A subset of activated fibroblasts is associated with distant relapse in early luminal breast cancer
2020 · Claire Bonneau, Antoine Eliès, et al. · Breast Cancer Research · 78
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WNT-dependent interaction between inflammatory fibroblasts and FOLR2+ macrophages promotes fibrosis in chronic kidney disease
2024 · Camille Cohen, Rana Mhaidly, et al. · Nature Communications · 75
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MAP3K8/TPL-2/COT is a potential predictive marker for MEK inhibitor treatment in high-grade serous ovarian carcinomas
2015 · Tina Gruosso, Camille Garnier, et al. · Nature Communications · 70
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Residual ANTXR1+ myofibroblasts after chemotherapy inhibit anti-tumor immunity via YAP1 signaling pathway
2024 · Monika Licaj, Rana Mhaidly, et al. · Nature Communications · 68
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Discovery of Lung Cancer Biomarkers by Profiling the Plasma Proteome with Monoclonal Antibody Libraries
2011 · Mariana Guergova-Kuras, István Kurucz, et al. · Molecular & Cellular Proteomics · 59
Targeting the mitochondrial trifunctional protein restrains tumor growth in oxidative lung carcinomas
2021 · Nivea Dias Amoedo, Saharnaz Sarlak, et al. · Journal of Clinical Investigation · 57
AMOTL1 Promotes Breast Cancer Progression and Is Antagonized by Merlin
2016 · Christophe Couderc, Alizée Boin, et al. · Neoplasia · 47
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CD73-Mediated Immunosuppression Is Linked to a Specific Fibroblast Population That Paves the Way for New Therapy in Breast Cancer
2021 · Ilaria Magagna, Nicolas Gourdin, et al. · Cancers · 44
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A catalog of numerical centrosome defects in epithelial ovarian cancers
2022 · Jean‐Philippe Morretton, Anthony Simon, et al. · EMBO Molecular Medicine · 34
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Tumor-instructed glutamine synthesis in cancer-associated fibroblasts promotes pro-tumor macrophages
2025 · Xiaoyun Li, Sofie Hedlund Møller, et al. · The Journal of Experimental Medicine · 28
Cancer-associated fibroblasts produce matrix-bound vesicles that influence endothelial cell function
2024 · Alice Santi, Emily J. Kay, et al. · Science Signaling · 28
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E-Cadherin Mutational Landscape and Outcomes in Breast Invasive Lobular Carcinoma
2024 · Lounes Djerroudi, Amel Bendali, et al. · Modern Pathology · 24
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Clinical Interest of Combining Transcriptomic and Genomic Signatures in High-Grade Serous Ovarian Cancer
2020 · Yann Kieffer, Claire Bonneau, et al. · Frontiers in Genetics · 23
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Works count: 107
Citation count: 5,651
H-index: 24
I10-index: 28
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