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Anne F. McGettrick

Observed names: A F Mcgettrick, A MCGETTRICK, A. F. McGettrick, Anne F McGettrick, Anne F. McGETTRICK, Anne F. Mcgettrick, Anne. F. McGettrick
ORCID: 0000-0001-6887-7229
Observed ORCID: 0000-0001-6887-7229
OpenAlex ID: A5061944746
Succinate is an inflammatory signal that induces IL-1β through HIF-1α
2013 · G. M. Tannahill, A. M. Curtis, et al. · Nature · 4,285
Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1
2018 · Evanna L. Mills, Dylan G. Ryan, et al. · Nature · 1,924
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The Role of HIF in Immunity and Inflammation
2020 · Anne F. McGettrick, Luke A.J. O’Neill · Cell Metabolism · 783
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The Immunomodulatory Metabolite Itaconate Modifies NLRP3 and Inhibits Inflammasome Activation
2020 · Alexander Hooftman, Stefano Angiari, et al. · Cell Metabolism · 632
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Itaconate and itaconate derivatives target JAK1 to suppress alternative activation of macrophages
2022 · Marah C. Runtsch, Stefano Angiari, et al. · Cell Metabolism · 343
Circadian control of innate immunity in macrophages by miR-155 targeting Bmal1
2015 · Anne M. Curtis, Caio T. Fagundes, et al. · Proceedings of the National Academy of Sciences · 321
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Localisation and trafficking of Toll-like receptors: an important mode of regulation
2010 · Anne F McGettrick, Luke AJ O’Neill · Current Opinion in Immunology · 315
The myristoylation of TRIF-related adaptor molecule is essential for Toll-like receptor 4 signal transduction
2006 · Daniel C. Rowe, Anne F. McGettrick, et al. · Proceedings of the National Academy of Sciences · 289
Macrophage fumarate hydratase restrains mtRNA-mediated interferon production
2023 · Alexander Hooftman, Christian G. Peace, et al. · Nature · 247
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How Metabolism Generates Signals during Innate Immunity and Inflammation
2013 · Anne F. McGettrick, Luke A.J. O'Neill · Journal of Biological Chemistry · 232
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Pyruvate Kinase M2 Is Required for the Expression of the Immune Checkpoint PD-L1 in Immune Cells and Tumors
2017 · Eva M. Palsson-McDermott, Lydia Dyck, et al. · Frontiers in Immunology · 174
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The expanding family of MyD88-like adaptors in Toll-like receptor signal transduction
2004 · A MCGETTRICK · Molecular Immunology · 157
TAG, a splice variant of the adaptor TRAM, negatively regulates the adaptor MyD88–independent TLR4 pathway
2009 · Eva M Palsson-McDermott, Sarah L Doyle, et al. · Nature Immunology · 150
Trif-related adapter molecule is phosphorylated by PKCε during Toll-like receptor 4 signaling
2006 · Anne F. McGettrick, Elizabeth K. Brint, et al. · Proceedings of the National Academy of Sciences · 140
Toll‐like receptors: key activators of leucocytes and regulator of haematopoiesis
2007 · Anne F. McGettrick, Luke A. J. O'Neill · British Journal of Haematology · 110
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Glutathione Transferase Omega-1 Regulates NLRP3 Inflammasome Activation Through NEK7 Deglutathionylation
2019 · Mark M. Hughes, Alexander Hooftman, et al. · Cell Reports · 94
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Metabolic Messengers: itaconate
2024 · A. F. McGettrick, L. A. Bourner, et al. · Nature Metabolism · 89
Itaconate drives mtRNA-mediated type I interferon production through inhibition of succinate dehydrogenase
2024 · Shane M. O’Carroll, Christian G. Peace, et al. · Nature Metabolism · 79
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NLRP3 and IL ‐1 β in macrophages as critical regulators of metabolic diseases
2013 · A. F. McGettrick, L. A. J. O'Neill · Diabetes Obesity and Metabolism · 68
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The GOLD domain-containing protein TMED7 inhibits TLR4 signalling from the endosome upon LPS stimulation
2012 · Sarah L. Doyle, Harald Husebye, et al. · Nature Communications · 66
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Trypanosoma brucei metabolite indolepyruvate decreases HIF-1α and glycolysis in macrophages as a mechanism of innate immune evasion
2016 · Anne F. McGettrick, Sarah E. Corcoran, et al. · Proceedings of the National Academy of Sciences · 65
Intracellular Serine Protease Inhibitor SERPINB4 Inhibits Granzyme M-Induced Cell Death
2011 · Pieter J. A. de Koning, J. Alain Kummer, et al. · PLoS ONE · 56
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The GOLD Domain-containing Protein TMED1 Is Involved in Interleukin-33 Signaling*
2013 · Dympna J. Connolly, Luke A.J. O'Neill, et al. · Journal of Biological Chemistry · 55
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Endogenously produced itaconate negatively regulates innate-driven cytokine production and drives global ubiquitination in human macrophages
2024 · Luke A. Bourner, Linda A. Chung, et al. · Cell Reports · 50
Regulators of TLR4 Signaling by Endotoxins
2010 · Anne F. McGettrick, Luke A.J. O’Neill · Sub-cellular biochemistry/Subcellular biochemistry · 48
Works count: 41
Citation count: 10,990
H-index: 29
I10-index: 34
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