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Renée de Leeuw

A Hormone–DNA Repair Circuit Governs the Response to Genotoxic Insult
2013 · Jonathan F. Goodwin, Matthew J. Schiewer, et al. · Cancer Discovery · 368
MAPK Reliance via Acquired CDK4/6 Inhibitor Resistance in Cancer
2018 · Renée de Leeuw, Christopher McNair, et al. · Clinical Cancer Research · 131
A Role for Estrogen Receptor Phosphorylation in the Resistance to Tamoxifen
2011 · Renée de Leeuw, Jacques Neefjes, et al. · International Journal of Breast Cancer · 129
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The hinge region of the human estrogen receptor determines functional synergy between AF-1 and AF-2 in the quantitative response to estradiol and tamoxifen
2010 · Wilbert Zwart, Renée de Leeuw, et al. · Journal of Cell Science · 120
Targeting cell cycle and hormone receptor pathways in cancer
2013 · C E S Comstock, M A Augello, et al. · Oncogene · 119
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Novel Actions of Next-Generation Taxanes Benefit Advanced Stages of Prostate Cancer
2015 · Renée de Leeuw, Lisa D. Berman-Booty, et al. · Clinical Cancer Research · 98
PARP‐1 regulates DNA repair factor availability
2018 · Matthew J Schiewer, Amy C Mandigo, et al. · EMBO Molecular Medicine · 63
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Patient-derived Models Reveal Impact of the Tumor Microenvironment on Therapeutic Response
2018 · Ayesha A. Shafi, Matthew J. Schiewer, et al. · European Urology Oncology · 53
SLC36A1-mTORC1 signaling drives acquired resistance to CDK4/6 inhibitors
2019 · Akihiro Yoshida, Yiwen Bu, et al. · Science Advances · 47
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Serine-305 Phosphorylation Modulates Estrogen Receptor Alpha Binding to a Coregulator Peptide Array, with Potential Application in Predicting Responses to Tamoxifen
2012 · René Houtman, Renée de Leeuw, et al. · Molecular Cancer Therapeutics · 45
Mutant p53 elicits context-dependent pro-tumorigenic phenotypes
2021 · Jennifer J. McCann, Irina A. Vasilevskaya, et al. · Oncogene · 42
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PKA phosphorylation redirects ERα to promoters of a unique gene set to induce tamoxifen resistance
2012 · R de Leeuw, K Flach, et al. · Oncogene · 40
Pleiotropic Impact of DNA-PK in Cancer and Implications for Therapeutic Strategies
2019 · Emanuela Dylgjeri, Christopher McNair, et al. · Clinical Cancer Research · 33
Tumor cell heterogeneity and resistance; report from the 2018 Coffey‐Holden Prostate Cancer Academy Meeting
2018 · Andrea K. Miyahira, Robert B. Den, et al. · The Prostate · 24
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Petosemtamab (MCLA-158) with pembrolizumab as first-line (1L) treatment of PD-L1+ recurrent/metastatic (r/m) head and neck squamous cell carcinoma (HNSCC): Phase 2 trial.
2025 · Carla M.L. van Herpen, Amaury Daste, et al. · Journal of Clinical Oncology · 17
Abstract CT012: Clinical activity of MCLA-158 (petosemtamab), an IgG1 bispecific antibody targeting EGFR and LGR5, in advanced head and neck squamous cell cancer (HNSCC)
2023 · Ezra E. Cohen, Jérôme Fayette, et al. · Cancer Research · 14
Randomized Phase II Multicenter Trial of Abiraterone Acetate With or Without Cabazitaxel in the Treatment of Metastatic Castration-Resistant Prostate Cancer
2023 · Susan F. Slovin, Karen Knudsen, et al. · Journal of Clinical Oncology · 7
c15-153: Randomized phase IB/II study of enzalutamide with and without ribociclib in patients with metastatic castrate resistant, chemotherapy naïve prostate cancer that retains RB expression.
2018 · William Kevin Kelly, James Luke Godwin, et al. · Journal of Clinical Oncology · 3
Abstract CT156: MCLA-158 (petosemtamab), an IgG1 bispecific antibody targeting EGFR and LGR5, in advanced gastric/esophageal adenocarcinoma (GEA)
2023 · Marc Díez García, Antoine Hollebecque, et al. · Cancer Research · 2
Editorial: Response and Resistance in Castration-Resistant Prostate Cancer
2020 · Renée de Leeuw, Qi Cao, et al. · Frontiers in Oncology · 2
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Effect of bypass kinase pathways on acquired CDK4/6 inhibitor resistance.
2018 · Renee De Leeuw, Christopher McNair, et al. · Journal of Clinical Oncology · 1
Leveraging RB status to define therapy for castrate-resistant prostate cancer.
2014 · Renee de Leeuw, Clay de Comstock, et al. · Journal of Clinical Oncology · 1
Supplementary Table 1 from A Hormone–DNA Repair Circuit Governs the Response to Genotoxic Insult
2023 · Jonathan F. Goodwin, Matthew J. Schiewer, et al.
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Supplementary Figure Legends from A Hormone–DNA Repair Circuit Governs the Response to Genotoxic Insult
2023 · Jonathan F. Goodwin, Matthew J. Schiewer, et al.
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Supplementary Figure 7 from A Hormone–DNA Repair Circuit Governs the Response to Genotoxic Insult
2023 · Jonathan F. Goodwin, Matthew J. Schiewer, et al.
Works count: 72
Citation count: 1,359
H-index: 15
I10-index: 16
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