Author

Jewel L. Johnston

Observed names: Jewel L. Johnston, Jewel Johnston, Jewel L Johnston

Institution: Athira Pharma (United States)

Observed institution: Athira Pharma (United States)

ORCID: 0000-0003-2937-2919

Observed ORCID: 0000-0003-2937-2919

OpenAlex ID: A5062663435

Fosgonimeton, a Novel Positive Modulator of the HGF/MET System, Promotes Neurotrophic and Procognitive Effects in Models of Dementia

2022 · Jewel L. Johnston, Sherif M. Reda, et al. · Neurotherapeutics · 24

PDF

Fosgonimeton attenuates amyloid-beta toxicity in preclinical models of Alzheimer's disease

2024 · Sherif M. Reda, Sharay E. Setti, et al. · Neurotherapeutics · 7

PDF

ATH-1105, a small-molecule positive modulator of the neurotrophic HGF system, is neuroprotective, preserves neuromotor function, and extends survival in preclinical models of ALS

2024 · Andrée-Anne Berthiaume, Sherif M. Reda, et al. · Frontiers in Neuroscience · 5

Fosgonimeton, a novel, small molecule positive modulator of the HGF/MET system is neuroprotective in primary neuron culture

2022 · Sherif Reda, Jewel Johnston, et al. · Alzheimer s & Dementia · 5

Development of stable, orally bioavailable small molecule positive modulators of HGF/MET signaling for the treatment of cognitive impairment.

2022 · Robert W Taylor, Doug Boatman, et al. · Alzheimer s & Dementia · 2

Fosgonimeton attenuates amyloid‐β‐induced autophagic impairments in primary cortical neurons

2024 · Sherif M Reda, Wei Wu, et al. · Alzheimer s & Dementia · 1

PDF

ATH-1105 mitigates multiple pathologies in ALS models both alone and in combination with riluzole

2026 · Andrée-Anne Berthiaume, Kayla N. Kleist, et al. · Frontiers in Neurology

PDF

ATH-1105, a Small-molecule Positive Modulator of the Neurotrophic HGF System, is Neuroprotective in Co-culture of Human iPSC-derived Motor Neurons and Muscle (P9-11.025)

2025 · Sherif Reda, Wei Wu, et al. · Neurology

Neuroprotective effects of fosgonimeton and amyloid‐β‐targeting monoclonal antibodies against amyloid‐β toxicity in primary neuron culture

2024 · Sherif M Reda, Wei Wu, et al. · Alzheimer s & Dementia

PDF

Development of Novel Small Molecules Targeting Neurotrophic HGF Signaling for the Treatment of Alzheimer’s, Parkinson’s, and ALS

2024 · Robert W. Taylor, Andree-Anne Berthiaume, et al. · Neurotherapeutics

PDF

Targeting Neurotrophic HGF Signaling for the Treatment of Neurodegenerative Disorders (P11-4.003)

2024 · Kevin Church, Sherif Reda, et al. · Neurology

ATH‐1105, a small molecule positive modulator of the HGF/MET system, is neuroprotective and attenuates TDP‐43 protein pathology in ALS and frontotemporal dementia‐relevant preclinical models

2023 · Jewel L Johnston, Andrée‐Anne Berthiaume, et al. · Alzheimer s & Dementia

PDF

Fosgonimeton, a Small‐Molecule Positive Modulator of the HGF/MET System, Attenuates Amyloid‐β – Mediated Toxicity in Primary Neuron Culture

2023 · Sherif Reda, Wei Wu, et al. · Alzheimer s & Dementia

PDF

Small Molecule Positive Modulator of Hepatocyte Growth Factor (HGF)/MET, ATH-1105, Improves Function and Reduces Disease Biomarkers in a TDP-43 Mouse Model of Amyotrophic Lateral Sclerosis (P8-8.007)

2023 · Kayla Kleist, Andree-Anne Berthiaume, et al. · Neurology

Therapeutic Potential of Fosgonimeton, a Small-Molecule Positive Modulator of the Neurotrophic HGF/MET Pathway, in Neurodegenerative Conditions (S14.008)

2023 · Sherif Reda, Robert Taylor, et al. · Neurology

ATH-1105, a Small Molecule Positive Modulator of HGF/MET, is Neuroprotective and Preserves Motor and Nerve Function in a TDP-43 Mouse Model of ALS

2023 · Andrée-Anne Berthiaume, Sherif M. Reda, et al. · SSRN Electronic Journal

Works count: 16

Citation count: 44

H-index: 4

I10-index: 1