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Susan Cantin
Institution:
Jnana Therapeutics (United States)
Observed institutions:
Jnana Therapeutics (United States),
AstraZeneca (United States)
ORCID:
0000-0002-8674-8284
Observed ORCID:
0000-0002-8674-8284
OpenAlex ID:
A5062785500
Treatment with HC-070, a potent inhibitor of TRPC4 and TRPC5, leads to anxiolytic and antidepressant effects in mice
2018
·
Stefan Just
, Bertrand L. Chenard
, et al.
·
PLoS ONE
·
137
PDF
Systemic nano-delivery of low-dose STING agonist targeted to CD103+ dendritic cells for cancer immunotherapy
2022
·
Aatman S. Doshi
, Susan Cantin
, et al.
·
Journal of Controlled Release
·
65
STAT3 Antisense Oligonucleotide Remodels the Suppressive Tumor Microenvironment to Enhance Immune Activation in Combination with Anti–PD-L1
2020
·
Theresa A. Proia
, Maneesh Singh
, et al.
·
Clinical Cancer Research
·
63
PDF
XTX301, a Tumor-Activated Interleukin-12 Has the Potential to Widen the Therapeutic Index of IL12 Treatment for Solid Tumors as Evidenced by Preclinical Studies
2023
·
Ekta Patel
, Natalia V. Malkova
, et al.
·
Molecular Cancer Therapeutics
·
19
PDF
Novel Arginase Inhibitor, AZD0011, Demonstrates Immune Cell Stimulation and Antitumor Efficacy with Diverse Combination Partners
2023
·
Aatman S. Doshi
, Susan Cantin
, et al.
·
Molecular Cancer Therapeutics
·
16
Discovery of (2R,4R)-4-((S)-2-Amino-3-methylbutanamido)-2-(4-boronobutyl)pyrrolidine-2-carboxylic Acid (AZD0011), an Actively Transported Prodrug of a Potent Arginase Inhibitor to Treat Cancer
2024
·
Scott N. Mlynarski
, Brian M. Aquila
, et al.
·
Journal of Medicinal Chemistry
·
8
Abstract 4523: Inhibition of arginase in combination with anti-PDL1 leads to increased infiltration and activation of CD8+ T cells, NK cells, and CD103+ dendritic cells in mouse syngeneic tumor models
2020
·
Alwin Schuller
, Aatman Doshi
, et al.
·
Cancer Research
·
4
Abstract 1664: Inhibition of arginase in combination with radiation therapy shows increased immune-activation and anti-tumor activity in syngeneic tumor models
2021
·
Alwin Schuller
, Aatman Doshi
, et al.
·
Cancer Research
·
2
Supplementary Table S2 from XTX301, a Tumor-Activated Interleukin-12 Has the Potential to Widen the Therapeutic Index of IL12 Treatment for Solid Tumors as Evidenced by Preclinical Studies
2026
·
Ekta Patel
, Natalia V. Malkova
, et al.
Supplementary Figure S7 from XTX301, a Tumor-Activated Interleukin-12 Has the Potential to Widen the Therapeutic Index of IL12 Treatment for Solid Tumors as Evidenced by Preclinical Studies
2026
·
Ekta Patel
, Natalia V. Malkova
, et al.
Supplementary Figure S3 from XTX301, a Tumor-Activated Interleukin-12 Has the Potential to Widen the Therapeutic Index of IL12 Treatment for Solid Tumors as Evidenced by Preclinical Studies
2026
·
Ekta Patel
, Natalia V. Malkova
, et al.
Supplementary Figure S6 from XTX301, a Tumor-Activated Interleukin-12 Has the Potential to Widen the Therapeutic Index of IL12 Treatment for Solid Tumors as Evidenced by Preclinical Studies
2026
·
Ekta Patel
, Natalia V. Malkova
, et al.
Supplementary Table S3 from XTX301, a Tumor-Activated Interleukin-12 Has the Potential to Widen the Therapeutic Index of IL12 Treatment for Solid Tumors as Evidenced by Preclinical Studies
2026
·
Ekta Patel
, Natalia V. Malkova
, et al.
Supplementary Figure S5 from XTX301, a Tumor-Activated Interleukin-12 Has the Potential to Widen the Therapeutic Index of IL12 Treatment for Solid Tumors as Evidenced by Preclinical Studies
2026
·
Ekta Patel
, Natalia V. Malkova
, et al.
Supplementary Table S1 from XTX301, a Tumor-Activated Interleukin-12 Has the Potential to Widen the Therapeutic Index of IL12 Treatment for Solid Tumors as Evidenced by Preclinical Studies
2026
·
Ekta Patel
, Natalia V. Malkova
, et al.
Supplementary Figure S2 from XTX301, a Tumor-Activated Interleukin-12 Has the Potential to Widen the Therapeutic Index of IL12 Treatment for Solid Tumors as Evidenced by Preclinical Studies
2026
·
Ekta Patel
, Natalia V. Malkova
, et al.
Supplementary Figure S1 from XTX301, a Tumor-Activated Interleukin-12 Has the Potential to Widen the Therapeutic Index of IL12 Treatment for Solid Tumors as Evidenced by Preclinical Studies
2026
·
Ekta Patel
, Natalia V. Malkova
, et al.
Supplementary Figure S4 from XTX301, a Tumor-Activated Interleukin-12 Has the Potential to Widen the Therapeutic Index of IL12 Treatment for Solid Tumors as Evidenced by Preclinical Studies
2026
·
Ekta Patel
, Natalia V. Malkova
, et al.
Effects of acute inhibition of solute carrier family 6 member 19 on plasma and brain amino acid levels and on neurotransmitters in a mouse model of phenylketonuria
2026
·
Heike Wobst
, Ryan Philbin
, et al.
·
Molecular Genetics and Metabolism
Supplementary Figure 2 from Novel Arginase Inhibitor, AZD0011, Demonstrates Immune Cell Stimulation and Antitumor Efficacy with Diverse Combination Partners
2025
·
Aatman S. Doshi
, Susan Cantin
, et al.
Supplementary Table 1 from Novel Arginase Inhibitor, AZD0011, Demonstrates Immune Cell Stimulation and Antitumor Efficacy with Diverse Combination Partners
2025
·
Aatman S. Doshi
, Susan Cantin
, et al.
Supplementary Figure 4 from Novel Arginase Inhibitor, AZD0011, Demonstrates Immune Cell Stimulation and Antitumor Efficacy with Diverse Combination Partners
2025
·
Aatman S. Doshi
, Susan Cantin
, et al.
Supplementary Figure 3 from Novel Arginase Inhibitor, AZD0011, Demonstrates Immune Cell Stimulation and Antitumor Efficacy with Diverse Combination Partners
2025
·
Aatman S. Doshi
, Susan Cantin
, et al.
Supplementary Figure 5 from Novel Arginase Inhibitor, AZD0011, Demonstrates Immune Cell Stimulation and Antitumor Efficacy with Diverse Combination Partners
2025
·
Aatman S. Doshi
, Susan Cantin
, et al.
Supplementary Figure 1 from Novel Arginase Inhibitor, AZD0011, Demonstrates Immune Cell Stimulation and Antitumor Efficacy with Diverse Combination Partners
2025
·
Aatman S. Doshi
, Susan Cantin
, et al.
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Works count:
96
Citation count:
314
H-index:
6
I10-index:
5
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