Get started
Author

Carmen L. Laethem

Observed names: C L Laethem, C. L. Laethem, C.L. Laethem, Carmen Laethem, Laethem, Carmen, Laethem, Carmen L, Laethem, Carmen L.
OpenAlex ID: A5062950132
Formation of 19(S)-, 19(R)-, and 18(R)-hydroxyeicosatetraenoic acids by alcohol-inducible cytochrome P450 2E1
1993 · R.M. Laethem, M. Balazy, et al. · Journal of Biological Chemistry · 203
Discovery and Preclinical Development of Netarsudil, a Novel Ocular Hypotensive Agent for the Treatment of Glaucoma
2017 · Cheng-Wen Lin, Bryan Sherman, et al. · Journal of Ocular Pharmacology and Therapeutics · 187
Identification of ethanol-inducible P450 isozyme 3a (P450IIE1) as a benzene and phenol hydroxylase
1989 · Dennis R. Koop, Carmen L. Laethem, et al. · Toxicology and Applied Pharmacology · 137
Discovery of the ROCK inhibitor netarsudil for the treatment of open-angle glaucoma
2016 · Jill M. Sturdivant, Susan M. Royalty, et al. · Bioorganic & Medicinal Chemistry Letters · 100
The Utility of p-Mtrophenol Hydroxylation in P450iie1 Analysis
1989 · Dennis R. Koop, Carmen L. Laethem, et al. · Drug Metabolism Reviews · 87
Secretion of Proinflammatory Cytokines and Chemokines during Amphotericin B Exposure Is Mediated by Coactivation of Toll-Like Receptors 1 and 2
2005 · Raymund R. Razonable, Martin Henault, et al. · Antimicrobial Agents and Chemotherapy · 62
Identification and induction of cytochromes P450, P450IIE1 and P450IA1 in rabbit bone marrow.
1989 · G G Schnier, C L Laethem, et al. · Journal of Pharmacology and Experimental Therapeutics · 54
Purification and properties of a cytochrome P450 arachidonic acid epoxygenase from rabbit renal cortex.
1992 · R.M. Laethem, C.L. Laethem, et al. · Journal of Biological Chemistry · 49
Generation and Characterization of a Stable MK2‐EGFP Cell Line and Subsequent Development of a High‐Content Imaging Assay on the Cellomics ArrayScan Platform to Screen for p38 Mitogen‐Activated Protein Kinase Inhibitors
2006 · Rhonda Gates Williams, Ramani Kandasamy, et al. · Methods in enzymology on CD-ROM/Methods in enzymology · 32
Assay Development and Case History of a 32K‐Biased Library High‐Content MK2‐EGFP Translocation Screen to Identify p38 Mitogen‐Activated Protein Kinase Inhibitors on the ArrayScan 3.1 Imaging Platform
2006 · Oscar J. Trask, Audrey Baker, et al. · Methods in enzymology on CD-ROM/Methods in enzymology · 30
P-450-dependent arachidonic acid metabolism in rabbit olfactory microsomes.
1992 · R M Laethem, C L Laethem, et al. · Journal of Pharmacology and Experimental Therapeutics · 25
Development and Implementation of Three Mitogen‐Activated Protein Kinase (MAPK) Signaling Pathway Imaging Assays to Provide MAPK Module Selectivity Profiling for Kinase Inhibitors: MK2‐EGFP Translocation, c‐Jun, and ERK Activation
2006 · Debra Nickischer, Carmen Laethem, et al. · Methods in enzymology on CD-ROM/Methods in enzymology · 21
Configuring Radioligand Receptor Binding Assays for HTS Using Scintillation Proximity Assay Technology
2003 · John W. Carpenter, Carmen Laethem, et al. · Humana Press eBooks · 21
Chloroform-Induced Cytolethality in Freshly Isolated Male B6C3F1Mouse and F-344 Rat Hepatocytes
1998 · Pierre Ammann, Carmen L. Laethem, et al. · Toxicology and Applied Pharmacology · 16
Role of eicosanoids in vasopressin-induced calcium mobilization in A7r5 vascular smooth muscle cells
1993 · M. Thibonnier, A. L. Bayer, et al. · American Journal of Physiology-Endocrinology and Metabolism · 12
Inhibition of rabbit microsomal cytochrome P-450 2E1-dependent p-nitrophenol hydroxylation by substituted benzene derivatives.
1992 · D R Koop, C L Laethem · Drug Metabolism and Disposition · 11
Works count: 22
Citation count: 1,047
H-index: 14
I10-index: 16
Year
Topic
Type