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Sheila Hobbs DeWitt

Observed names: S H DeWitt, S Hobbs Dewitt, S. H. DEWITT, S. HOBBS DEWITT, Sheila DeWitt, Sheila Dewitt, Sheila H DeWitt, Sheila H. DeWitt, Sheila H. Dewitt, Sheila Hobbs De Witt, Sheila Hobbs Dewitt
ORCID: 0000-0003-0354-177X
Observed ORCID: 0000-0003-0354-177X
OpenAlex ID: A5064085290
"Diversomers": an approach to nonpeptide, nonoligomeric chemical diversity.
1993 · S H DeWitt, J S Kiely, et al. · Proceedings of the National Academy of Sciences · 340
Deuterated Drug Molecules: Focus on FDA-Approved Deutetrabenazine
2017 · Sheila H. DeWitt, Bruce E. Maryanoff · Biochemistry · 177
Combinatorial Organic Synthesis Using Parke-Davis's DIVERSOMER Method
1996 · Sheila Hobbs DeWitt, Anthony W. Czarnik · Accounts of Chemical Research · 140
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Micro reactors for chemical synthesis
1999 · Sheila H DeWitt · Current Opinion in Chemical Biology · 120
Differentiation of antiinflammatory and antitumorigenic properties of stabilized enantiomers of thalidomide analogs
2015 · Vincent Jacques, Anthony W. Czarnik, et al. · Proceedings of the National Academy of Sciences · 111
A practical guide to combinatorial chemistry
1997 · Anthony W. Czarnik, Sheila H. DeWitt · American Chemical Society eBooks · 106
Evaluation of PXL065 – deuterium-stabilized (R)-pioglitazone in patients with NASH: A phase II randomized placebo-controlled trial (DESTINY-1)
2023 · Stephen A. Harrison, Carole Thang, et al. · Journal of Hepatology · 94
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A solid phase approach to quinolones using the DIVERSOMER® technology
1996 · Alasdair A MacDonald, Sheila H DeWitt, et al. · Tetrahedron Letters · 64
Deuterium‐Stabilized (R)‐Pioglitazone (PXL065) Is Responsible for Pioglitazone Efficacy in NASH yet Exhibits Little to No PPARγ Activity
2021 · Vincent Jacques, Sébastien Bolze, et al. · Hepatology Communications · 50
Deuterium-Enabled Chiral Switching (DECS) Yields Chirally Pure Drugs from Chemically Interconverting Racemates
2020 · Sheila DeWitt, Anthony W. Czarnik, et al. · ACS Medicinal Chemistry Letters · 44
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DIVERSOMERTM technology: Solid phase synthesis, automation, and integration for the generation of chemical diversity
1994 · Sheila Hobbs Dewitt, Mel C. Schroeder, et al. · Drug Development Research · 27
Automated synthesis and combinatorial chemistry
1995 · Sheila H DeWitt, Anthony W Czarnik · Current Opinion in Biotechnology · 26
The impact of polystyrene resins in solid-phase organic synthesis
1996 · Alasdair A. MacDonald, Sheila H. Dewitt, et al. · Molecular Diversity · 21
Therapeutic potential of deuterium‐stabilized (R)‐pioglitazone— PXL065 —for X‐linked adrenoleukodystrophy
2022 · Pierre‐Axel Monternier, Jaspreet Singh, et al. · Journal of Inherited Metabolic Disease · 17
CD4 similarity to proteins of infectious agents in AIDS and their role in autoimmunity
1994 · R.S Root-Bernstein, S Hobbs Dewitt · Medical Hypotheses · 12
Semen alloantigens and lymphocytotoxic antibodies in AIDS and ICL
1995 · Robert S. Root-Bernstein, Sheila Hobbs DeWitt · Genetica · 11
Consideration of Solid-Phase Synthesis with Reference to Quinolone Antibiotics
1996 · Alasdair A. Macdonald, Sheila H. DeWitt, et al. · CHIMIA International Journal for Chemistry · 7
Fabrication and characterization of three-dimensional microfluidic arrays
1999 · Sheldon M. Kugelmass, Chao Lin, et al. · Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE · 6
Automated synthesis
1997 · Sheila H. DeWitt · Annual reports in combinatorial chemistry and molecular diversity · 5
SP-3164, a Novel Cereblon-Binding Protein Degrader, Shows Activity in Preclinical Lymphoma Models
2022 · Daniela Y Santiesteban, Aundrietta D Duncan, et al. · Blood · 2
Laboratory Automation in Chemical Development
1999 · Martin R. Owen, Sheila H. Dewitt · CRC Press eBooks · 2
Abstract 524: SP-3164, a novel ikaros and aiolos molecular glue degrader with preclinical activity in non-Hodgkin lymphomas
2023 · Daniela Y. Santiesteban, Aundrietta D. Duncan, et al. · Cancer Research · 1
Abstract 6253: SP-3164, a novel molecular glue degrader with activity in preclinical models of multiple myeloma
2023 · Aundrietta D. Duncan, Daniela Y. Santiesteban, et al. · Cancer Research · 1
ChemInform Abstract: Parallel Organic Synthesis Using Parke—Davis Diversomer Technology
1999 · Sheila Hobbs DeWitt, Anthony W. Czarnik · ChemInform · 1
ChemInform Abstract: A Modular System for Combinatorial and Automated Synthesis
1997 · S. H. DEWITT, B. R. BEAR, et al. · ChemInform · 1
Works count: 35
Citation count: 1,386
H-index: 14
I10-index: 16
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