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Koen D. Flach

Observed names: Flach, K.D., K Flach, Koen D Flach, Koen Dorus Flach, Koen Flach
OpenAlex ID: A5064118435
Interaction of 14-3-3 proteins with the Estrogen Receptor Alpha F domain provides a drug target interface
2013 · Ingrid J. De Vries-van Leeuwen, Daniel da Costa Pereira, et al. · Proceedings of the National Academy of Sciences · 149
Co-regulated gene expression by oestrogen receptor α and liver receptor homolog-1 is a feature of the oestrogen response in breast cancer cells
2013 · Chun-Fui Lai, Koen D. Flach, et al. · Nucleic Acids Research · 57
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MAPK p38 and JNK have opposing activities on TRAIL-induced apoptosis activation in NSCLC H460 cells that involves RIP1 and caspase-8 and is mediated by Mcl-1
2013 · Kaamar Azijli, Saravanan Yuvaraj, et al. · APOPTOSIS · 49
Comparative Cistromics Reveals Genomic Cross-talk between FOXA1 and ERα in Tamoxifen-Associated Endometrial Carcinomas
2016 · Marjolein Droog, Ekaterina Nevedomskaya, et al. · Cancer Research · 41
PKA phosphorylation redirects ERα to promoters of a unique gene set to induce tamoxifen resistance
2012 · R de Leeuw, K Flach, et al. · Oncogene · 39
A Mediator-cohesin axis controls heterochromatin domain formation
2022 · Judith H. I. Haarhuis, Robin H. van der Weide, et al. · Nature Communications · 38
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Endonuclease FEN1 Coregulates ERα Activity and Provides a Novel Drug Interface in Tamoxifen-Resistant Breast Cancer
2020 · Koen D. Flach, Manikandan Periyasamy, et al. · Cancer Research · 33
A CRISPR-Cas9 screen identifies essential CTCF anchor sites for estrogen receptor-driven breast cancer cell proliferation
2019 · Gozde Korkmaz, Zohar Manber, et al. · Nucleic Acids Research · 29
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Distinct roles for CKM–Mediator in controlling Polycomb-dependent chromosomal interactions and priming genes for induction
2022 · Emilia Dimitrova, Angelika Feldmann, et al. · Nature Structural & Molecular Biology · 26
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Perturbations in 3D genome organization can promote acquired drug resistance
2023 · Anna G. Manjón, Stefano Giustino Manzo, et al. · Cell Reports · 25
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The first decade of estrogen receptor cistromics in breast cancer
2016 · Koen D Flach, Wilbert Zwart · Journal of Endocrinology · 22
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SRC3 Phosphorylation at Serine 543 Is a Positive Independent Prognostic Factor in ER-Positive Breast Cancer
2015 · Wilbert Zwart, Koen D. Flach, et al. · Clinical Cancer Research · 17
A 3D genome compendium of breast cancer progression
2025 · Teun van den Brand, Maria Donaldson Collier, et al. · iScience · 7
Dissecting the predictive value of MAPK/AKT/estrogen-receptor phosphorylation axis in primary breast cancer to treatment response for tamoxifen over exemestane: a Translational Report of the Intergroup Exemestane Study (IES)—PathIES
2019 · Zsolt Szijgyarto, Koen D. Flach, et al. · Breast Cancer Research and Treatment · 7
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Cohesin-mediated loop extrusion and enhancer-associated factors additively contribute to Sox2 looping with its distal enhancer
2026 · Moreno Martinovic, Koen D. Flach, et al. · Genes & Development · 1
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Suppl Figure and table legends from SRC3 Phosphorylation at Serine 543 Is a Positive Independent Prognostic Factor in ER-Positive Breast Cancer
2023 · Wilbert Zwart, Koen D. Flach, et al.
Table S4 from SRC3 Phosphorylation at Serine 543 Is a Positive Independent Prognostic Factor in ER-Positive Breast Cancer
2023 · Wilbert Zwart, Koen D. Flach, et al.
Table S6 from SRC3 Phosphorylation at Serine 543 Is a Positive Independent Prognostic Factor in ER-Positive Breast Cancer
2023 · Wilbert Zwart, Koen D. Flach, et al.
Table S7: from SRC3 Phosphorylation at Serine 543 Is a Positive Independent Prognostic Factor in ER-Positive Breast Cancer
2023 · Wilbert Zwart, Koen D. Flach, et al.
Table S1 from SRC3 Phosphorylation at Serine 543 Is a Positive Independent Prognostic Factor in ER-Positive Breast Cancer
2023 · Wilbert Zwart, Koen D. Flach, et al.
Supplemtary Figures S 1-14 from SRC3 Phosphorylation at Serine 543 Is a Positive Independent Prognostic Factor in ER-Positive Breast Cancer
2023 · Wilbert Zwart, Koen D. Flach, et al.
Table S5 from SRC3 Phosphorylation at Serine 543 Is a Positive Independent Prognostic Factor in ER-Positive Breast Cancer
2023 · Wilbert Zwart, Koen D. Flach, et al.
Table S2 from SRC3 Phosphorylation at Serine 543 Is a Positive Independent Prognostic Factor in ER-Positive Breast Cancer
2023 · Wilbert Zwart, Koen D. Flach, et al.
Table S3 from SRC3 Phosphorylation at Serine 543 Is a Positive Independent Prognostic Factor in ER-Positive Breast Cancer
2023 · Wilbert Zwart, Koen D. Flach, et al.
Supplemtary Figures S 1-14 from SRC3 Phosphorylation at Serine 543 Is a Positive Independent Prognostic Factor in ER-Positive Breast Cancer
2023 · Wilbert Zwart, Koen D. Flach, et al.
Works count: 57
Citation count: 540
H-index: 12
I10-index: 12
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