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Author

Paul A. Dutchak

Observed names: Dutchak, Paul A., Paul A Dutchak, Paul Dutchak, Paul A. Dutchak
Institution: Université Laval
ORCID: 0000-0002-7965-8870
Observed ORCID: 0000-0002-7965-8870
OpenAlex ID: A5064245409
Endocrine Regulation of the Fasting Response by PPARα-Mediated Induction of Fibroblast Growth Factor 21
2007 · Takeshi Inagaki, Paul Dutchak, et al. · Cell Metabolism · 1,501
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Fibroblast Growth Factor-21 Regulates PPARγ Activity and the Antidiabetic Actions of Thiazolidinediones
2012 · Paul A. Dutchak, Takeshi Katafuchi, et al. · Cell · 537
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Fibroblast growth factor 21 promotes bone loss by potentiating the effects of peroxisome proliferator-activated receptor γ
2012 · Wei Wei, Paul A. Dutchak, et al. · Proceedings of the National Academy of Sciences · 426
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Metabolic Networks Influencing Skeletal Muscle Fiber Composition
2018 · Isabelle Bourdeau Julien, Chantelle F. Sephton, et al. · Frontiers in Cell and Developmental Biology · 76
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Synaptic dysfunction in ALS and FTD: anatomical and molecular changes provide insights into mechanisms of disease
2022 · Pauline A. Gelon, Paul A. Dutchak, et al. · Frontiers in Molecular Neuroscience · 59
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Loss of a Negative Regulator of mTORC1 Induces Aerobic Glycolysis and Altered Fiber Composition in Skeletal Muscle
2018 · Paul A. Dutchak, Sandi J. Estill-Terpack, et al. · Cell Reports · 53
FUS contributes to mTOR-dependent inhibition of translation
2020 · Myriam Sévigny, Isabelle Bourdeau Julien, et al. · Journal of Biological Chemistry · 46
Regulation of Hematopoiesis and Methionine Homeostasis by mTORC1 Inhibitor NPRL2
2015 · Paul A. Dutchak, Sunil Laxman, et al. · Cell Reports · 45
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Antisense oligonucleotides targeting the miR-29b binding site in the GRN mRNA increase progranulin translation
2023 · Geetika Aggarwal, Subhashis Banerjee, et al. · Journal of Biological Chemistry · 18
NPRL2 Inhibition of mTORC1 Controls Sodium Channel Expression and Brain Amino Acid Homeostasis
2022 · Jeremy B. Hui, Jose Cesar Hernandez Silva, et al. · eNeuro · 15
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Neuronal dysfunction caused by FUSR521G promotes ALS-associated phenotypes that are attenuated by NF-κB inhibition
2023 · Mari Carmen Pelaez, Antoine Desmeules, et al. · Acta Neuropathologica Communications · 13
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A postzygotic de novo NCDN mutation identified in a sporadic FTLD patient results in neurochondrin haploinsufficiency and altered FUS granule dynamics
2022 · Gaël Nicolas, Myriam Sévigny, et al. · Acta Neuropathologica Communications · 9
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Targeting lipid droplets in FUS-linked amyotrophic lateral sclerosis mitigates neuronal and astrocytic lipotoxicity
2025 · Laetitia Marcadet, Mari Carmen Pelaez, et al. · Brain · 8
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GATOR1 Mutations Impair PI3 Kinase-Dependent Growth Factor Signaling Regulation of mTORC1
2024 · Maéline Muller, Jasmine Bélanger, et al. · International Journal of Molecular Sciences · 8
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RAPTOR-targeted Antisense Oligonucleotides Restrict Pathological mTORC1 Activity in GATOR1-dependent Disease
2026 · Imane Hadj-Aissa, Maéline Muller, et al. · bioRxiv (Cold Spring Harbor Laboratory)
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GATOR1 signaling defects promote astrocytic metabolic rewiring and excitatory neurotransmitter cycling
2026 · Imane Hadj-Aissa, Maéline Muller, et al. · EMBO Reports
Antisense oligonucleotides targeting miR‐29b binding site increase translation of progranulin protein: potential therapeutic strategy for progranulin‐deficient frontotemporal dementia
2022 · Geetika Aggarwal, Subhashis Banerjee, et al. · Alzheimer s & Dementia
Abstract B08: Altering cellular differentiation and energy metabolism by the mTORC1 inhibitor NPRL2
2016 · Paul A. Dutchak, SandiJo Terpack, et al. · Molecular Cancer Research
Metabolic Regulation by Fibroblast Growth Factor 21
2011 · Paul A. Dutchak
Works count: 23
Citation count: 2,814
H-index: 11
I10-index: 11
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