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Hossameldin A. Aziz

Observed names: Hossameldin Ali Aziz, Hossameldin Aziz
ORCID: 0009-0005-3165-3025
Observed ORCID: 0009-0005-3165-3025
OpenAlex ID: A5064276151
Thiazolidine-2,4-dione-linked ciprofloxacin derivatives with broad-spectrum antibacterial, MRSA and topoisomerase inhibitory activities
2021 · Hossameldin A. Aziz, Ahmed M. M. El-Saghier, et al. · Molecular Diversity · 42
Synthesis, Physicochemical Characterization using a Facile Validated HPLC Quantitation Analysis Method of 4-Chloro-phenylcarbamoyl-methyl Ciprofloxacin and Its Biological Investigations
2023 · Mostafa F. Al-Hakkani, Nourhan Ahmed, et al. · International Journal of Molecular Sciences · 26
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Unveiling the Anticancer Potential of a New Ciprofloxacin-Chalcone Hybrid as an Inhibitor of Topoisomerases I & II and Apoptotic Inducer
2024 · Doaa Mohamed Elroby Ali, Hossameldin A. Aziz, et al. · Molecules · 23
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Synthesis and antimicrobial evaluation of new nitric oxide‐donating fluoroquinolone/oxime hybrids
2020 · Hossameldin A. Aziz, Gamal A. I. Moustafa, et al. · Archiv der Pharmazie · 23
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Design, synthesis and mechanistic study of N-4-Piperazinyl Butyryl Thiazolidinedione derivatives of ciprofloxacin with Anticancer Activity via Topoisomerase I/II inhibition
2024 · Hossameldin A. Aziz, Ahmed M. El-Saghier, et al. · Scientific Reports · 21
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New fluoroquinolones/nitric oxide donor hybrids: design, synthesis and antitubercular activity
2019 · Hossameldin A. Aziz, Gamal A. I. Moustafa, et al. · Medicinal Chemistry Research · 17
New norfloxacin/nitric oxide donor hybrids: Synthesis and nitric oxide release measurement using a modified Griess colorimetric method
2017 · Hossameldin Ali Aziz, Gamal Abdeltawab Idris Moustafa, et al. · European Journal of Chemistry · 13
Design, Synthesis, Anticancer Screening, and Mechanistic Study of Spiro-N-(4-sulfamoyl-phenyl)-1,3,4-thiadiazole-2-carboxamide Derivatives
2025 · Ahmed M. El-Saghier, Hamada Hashem, et al. · International Journal of Molecular Sciences · 12
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Design, Synthesis, In Silico Docking, Multitarget Bioevaluation and Molecular Dynamic Simulation of Novel Pyrazolo[3,4-d]Pyrimidinone Derivatives as Potential In Vitro and In Vivo Anti-Inflammatory Agents
2025 · Mostafa Roshdi, Mamdouh F. A. Mohamed, et al. · Pharmaceuticals · 9
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Design, Synthesis, and In Silico Studies of New Norfloxacin Analogues with Broad Spectrum Antibacterial Activity via Topoisomerase II Inhibition
2025 · Ahmed M. El-Saghier, Laila Abosella, et al. · Pharmaceuticals · 9
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New norfloxacin analogues based on N-4-piperazinyl-(3-arylidene/alkylidene acrylonitrile) moieties: design, synthesis, antibacterial evaluation, and in silico studies
2025 · Ahmed M. El-Saghier, Laila Abosella, et al. · Monatshefte für Chemie - Chemical Monthly · 8
Design, Synthesis, and Mechanistic Study of Novel Ciprofloxacin/Thiazole Chalcone Hybrids as Potential Anticancer Agents
2025 · Hamada Hashem, Ali M. Elshamsy, et al. · Pharmaceuticals · 5
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Novel Pyrazole-3-Cyano-2-Pyridinone Hybrids as Multitarget Anti-Inflammatory Agents: Synthesis, Computational Modeling, and Biological Evaluation
2026 · Bahgat Hussein, Ibrahim Salem, et al. · Drug Design Development and Therapy · 3
Novel N-4-(5-Amino-7-substituted-triazolotriazinepiperazin-1-yl) Norfloxacin Analogues Exhibit Potent and Selective Anticancer Activity via Topoisomerase Inhibition, Cell-Cycle Arrest, and Apoptosis in A 431 Skin Carcinoma Cells
2026 · Ahmed M. El-Saghier, Amany M. Hamed, et al. · Pharmaceuticals · 2
Exploration of novel hydroxamic acid-based candidates integrating chalcone scaffold cap as multitarget HDAC inhibitors: design, anti-prostatic cancer assessment, in silico docking and molecular dynamic simulation
2026 · Aya I. Abd El-hameed, Ibrahim M. Salem, et al. · Journal of Enzyme Inhibition and Medicinal Chemistry · 1
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Works count: 15
Citation count: 214
H-index: 9
I10-index: 8
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