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Farokh Dotiwala
Observed name:
Farokh J Dotiwala
Institution:
Ocugen, Inc. (United States)
Observed institutions:
The Wistar Institute,
Boston Children's Hospital,
Harvard University,
Ocugen, Inc. (United States),
Brandeis University
ORCID:
0000-0002-7387-2219
Observed ORCID:
0000-0002-7387-2219
OpenAlex ID:
A5064794018
Cytotoxic T Cells Use Mechanical Force to Potentiate Target Cell Killing
2016
·
Roshni Basu
, Benjamin M. Whitlock
, et al.
·
Cell
·
499
PDF
Heterochromatin is refractory to γ-H2AX modification in yeast and mammals
2007
·
Jung-Ae Kim
, Michael Kruhlak
, et al.
·
The Journal of Cell Biology
·
276
PDF
Cytotoxic Cells Kill Intracellular Bacteria through Granulysin-Mediated Delivery of Granzymes
2014
·
Michael Walch
, Farokh Dotiwala
, et al.
·
Cell
·
236
PDF
Killer lymphocytes use granulysin, perforin and granzymes to kill intracellular parasites
2016
·
Farokh Dotiwala
, Sachin Mulik
, et al.
·
Nature Medicine
·
219
PDF
Smc5–Smc6 mediate DNA double-strand-break repair by promoting sister-chromatid recombination
2006
·
Giacomo De Piccoli
, Felipe Cortes-Ledesma
, et al.
·
Nature Cell Biology
·
200
Tumor-infiltrating mast cells are associated with resistance to anti-PD-1 therapy
2021
·
Rajasekharan Somasundaram
, Thomas Connelly
, et al.
·
Nature Communications
·
193
PDF
Decidual NK Cells Transfer Granulysin to Selectively Kill Bacteria in Trophoblasts
2020
·
Ângela C. Crespo
, Sachin Mulik
, et al.
·
Cell
·
182
PDF
Gene Therapy for Retinal Degenerative Diseases: Progress, Challenges, and Future Directions
2023
·
Selina Drag
, Farokh Dotiwala
, et al.
·
Investigative Ophthalmology & Visual Science
·
150
Resistance of HIV-infected macrophages to CD8+ T lymphocyte–mediated killing drives activation of the immune system
2018
·
Kiera L. Clayton
, David R. Collins
, et al.
·
Nature Immunology
·
147
Identification of regulators of the innate immune response to cytosolic DNA and retroviral infection by an integrative approach
2012
·
Mark N Lee
, Matthew Roy
, et al.
·
Nature Immunology
·
125
Cytotoxic CD8+ T cells recognize and kill Plasmodium vivax–infected reticulocytes
2018
·
Caroline Junqueira
, Camila R. R. Barbosa
, et al.
·
Nature Medicine
·
98
Mad2 Prolongs DNA Damage Checkpoint Arrest Caused by a Double-Strand Break via a Centromere-Dependent Mechanism
2010
·
Farokh Dotiwala
, Jacob C. Harrison
, et al.
·
Current Biology
·
97
PDF
Granzyme B Disrupts Central Metabolism and Protein Synthesis in Bacteria to Promote an Immune Cell Death Program
2017
·
Farokh Dotiwala
, Sumit Sen Santara
, et al.
·
Cell
·
89
PDF
Next Generation Mucosal Vaccine Strategy for Respiratory Pathogens
2023
·
Farokh Dotiwala
, Arun K. Upadhyay
·
Vaccines
·
71
PDF
Granulysin: killer lymphocyte safeguard against microbes
2019
·
Farokh Dotiwala
, Judy Lieberman
·
Current Opinion in Immunology
·
70
DNA damage checkpoint triggers autophagy to regulate the initiation of anaphase
2012
·
Farokh Dotiwala
, Vinay V. Eapen
, et al.
·
Proceedings of the National Academy of Sciences
·
68
RETRACTED ARTICLE: IspH inhibitors kill Gram-negative bacteria and mobilize immune clearance
2020
·
Kumar Sachin Singh
, Rishabh Sharma
, et al.
·
Nature
·
57
Human regulatory T cells undergo self-inflicted damage via granzyme pathways upon activation
2017
·
Esilida Sula Karreci
, Siawosh K. Eskandari
, et al.
·
JCI Insight
·
50
PDF
The yeast DNA damage checkpoint proteins control a cytoplasmic response to DNA damage
2007
·
Farokh Dotiwala
, Julian Haase
, et al.
·
Proceedings of the National Academy of Sciences
·
49
African-centric TP53 variant increases iron accumulation and bacterial pathogenesis but improves response to malaria toxin
2020
·
Kumar Sachin Singh
, Julia I-Ju Leu
, et al.
·
Nature Communications
·
45
PDF
Cytotoxic Cells Kill Intracellular Bacteria through Granulysin-Mediated Delivery of Granzymes
2015
·
Michael Walch
, Farokh Dotiwala
, et al.
·
Cell
·
30
PDF
Geographic atrophy: pathophysiology and current therapeutic strategies
2023
·
Kalpana Rajanala
, Farokh Dotiwala
, et al.
·
Frontiers in Ophthalmology
·
23
PDF
ONP-302 Nanoparticles Inhibit Tumor Growth By Altering Tumor-Associated Macrophages And Cancer-Associated Fibroblasts
2022
·
Laxminarasimha Donthireddy
, Prashanthi Vonteddu
, et al.
·
Journal of Cancer
·
15
PDF
A High Yield and Cost-efficient Expression System of Human Granzymes in Mammalian Cells
2015
·
Farokh Dotiwala
, Isabelle Fellay
, et al.
·
Journal of Visualized Experiments
·
13
A comprehensive review of BBV152 vaccine development, effectiveness, safety, challenges, and prospects
2022
·
Farokh Dotiwala
, Arun K. Upadhyay
·
Frontiers in Immunology
·
11
PDF
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Works count:
34
Citation count:
3,031
H-index:
22
I10-index:
25
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