Author

Lawrence M. Gelbert

Observed names: Gelbert, Lawrence, L Gelbert, L M Gelbert, L. Gelbert, L. M. Gelbert, Lawrence Gelbert, Lawrence M Gelbert, Lawrence Mark. Gelbert (7990457)

Observed institutions: Indiana University Health, Howard Hughes Medical Institute, Eli Lilly (United States), University of Utah, Riley Hospital for Children, University of Illinois Chicago, Bristol-Myers Squibb (United States), Eli Lilly (Spain), Indiana University Indianapolis, Indiana University School of Medicine, Indiana University – Purdue University Indianapolis, Covance (United States)

OpenAlex ID: A5065087121

Identification and characterization of the familial adenomatous polyposis coli gene

1991 · Joanna Groden, Andrew Thliveris, et al. · Cell · 2,797

Identification of deletion mutations and three new genes at the familial polyposis locus

1991 · Geoff Joslyn, Mary Carlson, et al. · Cell · 767

Alleles of the APC gene: An attenuated form of familial polyposis

1993 · Lisa Spirio, Sylviane Olschwang, et al. · Cell · 622

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Preclinical characterization of the CDK4/6 inhibitor LY2835219: in-vivo cell cycle-dependent/independent anti-tumor activities alone/in combination with gemcitabine

2014 · Lawrence M. Gelbert, Shufen Cai, et al. · Investigational New Drugs · 572

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Brain Exposure of Two Selective Dual CDK4 and CDK6 Inhibitors and the Antitumor Activity of CDK4 and CDK6 Inhibition in Combination with Temozolomide in an Intracranial Glioblastoma Xenograft

2015 · Thomas J. Raub, Graham N. Wishart, et al. · Drug Metabolism and Disposition · 282

An Increase in the Expression of Ribonucleotide Reductase Large Subunit 1 Is Associated with Gemcitabine Resistance in Non-Small Cell Lung Cancer Cell Lines

2004 · Jennifer D. Davidson, Liandong Ma, et al. · Cancer Research · 280

Germ-line mutations in the von Hippel-Lindau tumor-suppressor gene are similar to somatic von Hippel-Lindau aberrations in sporadic renal cell carcinoma.

1994 · J M Whaley, J Naglich, et al. · PubMed · 232

Cyclin dependent kinase (CDK) inhibitors as anticancer drugs

2015 · Concepción Sánchez-Martínez, Lawrence M. Gelbert, et al. · Bioorganic & Medicinal Chemistry Letters · 230

Mutational analysis of patients with adenomatous polyposis: identical inactivating mutations in unrelated individuals.

1993 · J Groden, L Gelbert, et al. · PubMed · 141

Semi-Mechanistic Pharmacokinetic/Pharmacodynamic Modeling of the Antitumor Activity of LY2835219, a New Cyclin-Dependent Kinase 4/6 Inhibitor, in Mice Bearing Human Tumor Xenografts

2014 · Sonya C. Tate, Shufen Cai, et al. · Clinical Cancer Research · 129

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Mutations in the retinoblastoma-related gene RB2/p130 in lung tumors and suppression of tumor growth in vivo by retrovirus-mediated gene transfer.

2000 · P P Claudio, C M Howard, et al. · PubMed · 105

Molecular profile of catabolic versus anabolic treatment regimens of parathyroid hormone (PTH) in rat bone: An analysis by DNA microarray

2005 · Jude E. Onyia, Leah M. Helvering, et al. · Journal of Cellular Biochemistry · 101

Transcriptional Profiling of Keratinocytes Reveals a Vitamin D-Regulated Epidermal Differentiation Network

2005 · Jianfen Lu, Keith M. Goldstein, et al. · Journal of Investigative Dermatology · 85

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Estimating the Statistical Significance of Peptide Identifications from Shotgun Proteomics Experiments

2007 · Richard E. Higgs, Michael D. Knierman, et al. · Journal of Proteome Research · 66

Combination therapy in a xenograft model of glioblastoma: enhancement of the antitumor activity of temozolomide by an MDM2 antagonist

2016 · Haiyan Wang, Shanbao Cai, et al. · Journal of neurosurgery · 49

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Isolation and Characterization of Microsatellite Loci for Use in Population Genetic Analysis in the Timber Rattlesnake, Crotalus horridus

1996 · X. Villarreal, J. Bricker, et al. · Journal of Heredity · 43

Chromosomal localization of the parathyroid hormone/parathyroid hormone- related protein receptor gene to human chromosome 3p21.1-p24.2

1994 · L Gelbert, E Schipani, et al. · The Journal of Clinical Endocrinology & Metabolism · 36

Abstract B234: LY2835219, a potent oral inhibitor of the cyclin-dependent kinases 4 and 6 (CDK4/6) that crosses the blood-brain barrier and demonstrates in vivo activity against intracranial human brain tumor xenografts.

2011 · Concepcion Sanchez-Martinez, Lawrence M. Gelbert, et al. · Molecular Cancer Therapeutics · 31

Phencyclidine-induced changes in rat cortical gene expression identified by microarray analysis: implications for schizophrenia

2004 · Sergio Kaiser, Lisa A Foltz, et al. · Neurobiology of Disease · 31

Optimized blood cell profiling method for genomic biomarker discovery using high-density microarray

2005 · J. Shou, C. Dotson, et al. · Biomarkers · 23

Aldosterone stimulates angiotensin-converting enzyme expression and activity in rat neonatal cardiac myocytes

2002 · Jian Wang, Lan Yu, et al. · Journal of Cardiac Failure · 22

Clinical activity of abemaciclib in patients with relapsed or refractory mantle cell lymphoma - a phase II study

2020 · Franck Morschhauser, Kamal Bouabdallah, et al. · Haematologica · 20

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Clinical Activity of Abemaciclib (LY2835219), a Cell Cycle Inhibitor Selective for CDK4 and CDK6, in Patients with Relapsed or Refractory Mantle Cell Lymphoma

2014 · Franck Morschhauser, Kamal Bouabdallah, et al. · Blood · 20

Will genetics really revolutionize the drug discovery process?

1997 · Lawrence M Gelbert, Richard E Gregg · Current Opinion in Biotechnology · 18

Purification of high quality DNA from shed skin

1996 · J Bricker, Lauretta M. Bushar, et al. · Herpetological review · 18

Works count: 68

Citation count: 6,838

H-index: 21

I10-index: 32