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Chizuka Sakai

Observed names: C. Sakai, Sakai C Iwano S
ORCID: 0009-0006-1588-7486
Observed ORCID: 0009-0006-1588-7486
OpenAlex ID: A5065113464
Species Differences in the Pharmacokinetic Parameters of Cytochrome P450 Probe Substrates between Experimental Animals, such as Mice, Rats, Dogs, Monkeys, and Microminipigs, and Humans
2015 · Sakai C Iwano S · Journal of Drug Metabolism & Toxicology · 45
Synthesis and evaluation of novel dolastatin 10 derivatives for versatile conjugations
2018 · Shinya Yokosaka, Akiko Izawa, et al. · Bioorganic & Medicinal Chemistry · 20
Discovery of Peripheral κ-Opioid Receptor Agonists as Novel Analgesics
2017 · Shinya Suzuki, Yuji Sugawara, et al. · Chemical and Pharmaceutical Bulletin · 12
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Analysis of gene expression for microminipig liver transcriptomes using parallel long‐read technology and short‐read sequencing
2016 · Chizuka Sakai, Shunsuke Iwano, et al. · Biopharmaceutics & Drug Disposition · 8
Discovery of orally bioavailable inhibitors of MALT1 with in vivo activity for psoriasis
2023 · Ken Nunettsu Asaba, Keiichi Okimura, et al. · Bioorganic & Medicinal Chemistry Letters · 4
TXB-001, a newly-developed polymer-conjugated anthracycline: Significantly lower adverse effects in animal models of alopecia and hand-foot syndrome
2024 · Mikito Hirakata, Emi Tomikawa, et al. · Toxicology and Applied Pharmacology · 2
In vitro and in vivo intestinal and hepatic oxidative metabolism of typical cytochrome P450 3A substrates, midazolam, nifedipine, and quinidine, in minipigs: a comparison with humans, monkeys, and dogs
2026 · Chizuka Sakai, Eriko Higashi, et al. · Xenobiotica · 1
TXB-001, A Newly-Developed Polymer-Conjugated Anthracycline, Alleviates Anthracycline-Induced Cardiotoxicity
2025 · Miki Nonaka, Mikito Hirakata, et al. · Cardiovascular Toxicology · 1
Inhalation Toxicity of a Novel siRNA-Based Oligonucleotide, TRK-250 in Cynomolgus Monkeys
2019 · W. Toriumi, M. Uchida, et al. · American Journal of Respiratory and Critical Care Medicine · 1
In vitro and in vivo intestinal and hepatic oxidative metabolism of typical cytochrome P450 3A substrates, midazolam, nifedipine, and quinidine, in minipigs: a comparison with humans, monkeys, and dogs
2026 · Chizuka Sakai, Eriko Higashi, et al. · Figshare
Abstract 679: TXB-001 is an upgraded conjugated anthracycline that targets tumors with reduced risk of cardiotoxicity, hand-foot syndrome and alopecia
2024 · Keiyu Oshida, Mikito Hirakata, et al. · Cancer Research
Works count: 11
Citation count: 94
H-index: 4
I10-index: 3
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