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Eckhard Guenther

Observed names: E Guenther, E. + GUENTHER, E. G. Guenther, E. GUENTHER, E. Guenther, Eckhard G. Guenther, Guenther, Eckhard
Observed institutions: Centre National de la Recherche Scientifique, University of Würzburg, Aeterna Zentaris (Germany), University of Regensburg, Martin Luther University Halle-Wittenberg, Nantes Université
OpenAlex ID: A5065186410
Translational potential of the ghrelin receptor agonist macimorelin for seizure suppression in pharmacoresistant epilepsy
2021 · An Buckinx, Anouk Pierre, et al. · European Journal of Neurology · 12
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Abstract C214: Disorazol Z: A highly cytotoxic natural compound with antitumor properties.
2011 · Babette Aicher, Kerstin Hirschfelder, et al. · Molecular Cancer Therapeutics · 6
New generation of anilino-substituted pyridopyrazine-urea derivatives show highly selective PI3K-inhibition
2007 · Irene Seipelt, Eckhard Claus, et al. · Cancer Research · 5
330 Highly Potent Cytotoxic Conjugates of Disorazol Z Linked to a LHRH Receptor Targeting Peptide Interfere with Cell Cycle Progression in Human Cancer Cell Lines and Suppress Tumor Growth in a LHRH Receptor Positive Ovarian Cancer Xenograft Model
2012 · B. Aicher, T. Schuster, et al. · European Journal of Cancer · 3
Abstract 871: Dual inhibition of PI3K and Erk1/2 shows synergy and efficacy in human tumor cells, either by using drug combinations or novel dual PI3K/Erk inhibitors
2012 · Irene Seipelt, Matthias Gerlach, et al. · Cancer Research · 3
MP-02.03: The LHRH Receptor Antagonist Cetrorelix Exhibits Agonistic Activity Against the Orphan GPCR Mrgx2: A Novel Mode of Action?
2009 · B. Aicher, P. Schmidt, et al. · Urology · 2
525 POSTER Targeting Doxorubicin to LHRH-receptor positive tumors by the cytotoxic hybrid ZEN-008 (AN-152)
2006 · E. Guenther, M. Teifel, et al. · European Journal of Cancer Supplements · 2
Abstract 5476: LHRH receptor targeting as mechanism of anti-tumor activity for cytotoxic conjugates of Disorazol Z with the LHRH receptor agonistic peptide D-Lys6-LHRH.
2013 · Babette Aicher, Tilmann Schuster, et al. · Cancer Research · 1
Abstract 2877: Perifosine alone and in combination with antimetabolites interferes with NF-kB pathway activation in colon cancer cell lines
2012 · Babette Aicher, Peter Schmidt, et al. · Cancer Research · 1
ChemInform Abstract: A Convenient Synthesis of Novel 2,8‐Disubstituted Pyrido[3,4‐b]pyrazines Possessing Biological Activity.
2012 · Maud Antoine, Matthias Gerlach, et al. · ChemInform · 1
ChemInform Abstract: Preparation of Novel 2,3,8‐Trisubstituted Pyrido[3,4‐b]pyrazines and Pyrido[2,3‐b]pyrazines.
2011 · Maud Antoine, Michael Czech, et al. · ChemInform · 1
Abstract 3563: A highly selective Erk1/2 Inhibitor with in-vivo anti tumor potency
2011 · Irene Seipelt, Eckhard Guenther, et al. · Cancer Research · 1
Cytotoxic conjugates of Disorazol Z with the LHRH receptor agonistic peptide D-Lys(6)-LHRH as approach to targeted therapy of LHRH-R positive tumors
2013 · Gerlach, Matthias, Aicher, Babette, et al. · GRO
197 AEZS-132, a new orally bioavailable PI3K/Erk inhibitor with antitumor effects
2010 · I. Seipelt, M. Gerlach, et al. · European Journal of Cancer Supplements
98 AEZS-129, an orally active PI3K inhibitor in preclinical development
2010 · I. Seipelt, E. Guenther, et al. · European Journal of Cancer Supplements
Abstract 4474: Dual inhibitors for PI3K and Erk induce growth inhibition of tumor cells
2010 · Irene Seipelt, Matthias Gerlach, et al. · Cancer Research
Abstract 3856: A highly selective Erk-inhibitor with antiproliferative efficacy and the potential for combination therapy with modulators of the PI3K pathway
2010 · Irene Seipelt, Lars Blumenstein, et al. · Cancer Research
Development of AEZS-115 (ZEN-019) by Optimization of Structurally Unique, Orally Active, Peptidomimetic GnRH Antagonists
2009 · K. W. Paulini, S. Baasner, et al. · Advances in experimental medicine and biology
Orally active gnRH-antagonist AEZS-115 inhibits growth of human ovarian and breast cancers in vitro.
2009 · JB Engel, M Ivanisevic, et al. · Cancer Research
Highly potent cytotoxic compounds with inhibitory effects on tubulin polymerization and topoisomerase II
2007 · Babette Aicher, Péter Schmidt, et al. · Molecular Cancer Therapeutics
291 POSTER Lobaplatin – A third-generation platinum agent with hight in vitro efficacy across a wide range of cancer cells
2006 · E. Guenther, P. Schmidt, et al. · European Journal of Cancer Supplements
Disorazol E1 A natural compound with outstanding in vitro antitumor activity
2003 · Silke Baasner, M. Gerlach, et al. · Proceedings of the American Association for Cancer Research Annual Meeting
Evariquinone (I), Isoemericellin (II), and Stromemycin (III) from a Sponge‐Derived Strain of the Fungus Emericella variecolor.
2003 · Gerhard Bringmann, Gerhard Lang, et al. · ChemInform
ChemInform Abstract: Syntheses of Racemic and Non‐racemic Silicon‐ and Germanium‐Containing α‐Amino Acids of the Formula Type H2NCH(CH2ElR3)COOH (El: Si, Ge; R = Organyl) and Incorporation of D‐H2NCH(CH2SiMe3)COOH and D‐H2NCH(CH2GeMe3)COOH into Biologically Active Decapeptides: A Study on C/Si/Ge Bioisosterism.
2001 · Markus Merget, Kurt Guenther, et al. · ChemInform
ChemInform Abstract: Multistep Reversible Redox Systems. Part 59. Conducting Charge‐ Transfer Complexes of 2,5‐Bis(cyanoimino)‐2,5‐dihydrothieno(3,2‐b) thiophenes with Organic Donors.
1992 · E. GUENTHER, S. HUENIG, et al. · ChemInform
Works count: 34
Citation count: 38
H-index: 3
I10-index: 1
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