Author

Sylvia Mahara

Observed name: SYLVIA MAHARA

Institution: German Cancer Research Center

Observed institutions: Agency for Science, Technology and Research, National University of Singapore, German Cancer Research Center, Hudson Institute of Medical Research, University of Oxford, Monash Health, Cancer Science Institute of Singapore, Monash University, Genome Institute of Singapore

ORCID: 0000-0001-7261-1423

Observed ORCID: 0000-0001-7261-1423

OpenAlex ID: A5065624192

Hypoxic tumor microenvironment activates GLI2 via HIF-1α and TGF-β2 to promote chemoresistance in colorectal cancer

2018 · Yen-An Tang, Yu-feng Chen, et al. · Proceedings of the National Academy of Sciences · 275

The histone methyltransferase inhibitor, DZNep, up-regulates TXNIP, increases ROS production, and targets leukemia cells in AML

2011 · Jianbiao Zhou, Chonglei Bi, et al. · Blood · 214

HIFI-α activation underlies a functional switch in the paradoxical role of Ezh2/PRC2 in breast cancer

2016 · Sylvia Mahara, Puay Leng Lee, et al. · Proceedings of the National Academy of Sciences · 87

Genome-scale CRISPR-Cas9 screen of Wnt/β-catenin signaling identifies therapeutic targets for colorectal cancer

2021 · Chunhua Wan, Sylvia Mahara, et al. · Science Advances · 66

PRL-3, a Metastasis Associated Tyrosine Phosphatase, Is Involved in FLT3-ITD Signaling and Implicated in Anti-AML Therapy

2011 · Jianbiao Zhou, Chonglei Bi, et al. · PLoS ONE · 66

Aged intestinal stem cells propagate cell-intrinsic sources of inflammaging in mice

2023 · Maja C. Funk, Jan G. Gleixner, et al. · Developmental Cell · 59

MED12 and BRD4 cooperate to sustain cancer growth upon loss of mediator kinase

2021 · Dhanya Sooraj, Claire Sun, et al. · Molecular Cell · 46

The pro-metastasis tyrosine phosphatase, PRL-3 (PTP4A3), is a novel mediator of oncogenic function of BCR-ABL in human chronic myeloid leukemia

2012 · Jianbiao Zhou, Lip-Lee Cheong, et al. · Molecular Cancer · 32

Molecular switch of EZH2 in hypoxia

2016 · Sylvia Mahara, Wee Joo Chng, et al. · Cell Cycle · 8

Transient promoter interactions modulate developmental gene activation

2024 · Sylvia Mahara, Sonja Prüssing, et al. · Molecular Cell · 5

The Pro-Metastasis Tyrosine Phosphatase, PRL-3 (PTP4A3), Is a Novel Target of BCR-ABL Signaling Involved in Human Chronic Myeloid Leukemia

2011 · Jianbiao Zhou, Lip-Lee Cheong, et al. · Blood · 1

Targeting the seeds of small cell lung cancer

2017 · Sylvia Mahara, Ron Firestein · Annals of Translational Medicine

Works count: 14

Citation count: 858

H-index: 8

I10-index: 8