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Author

Peter Dogterom

Observed names: P Dogterom, P. Dogterom
Observed institutions: Leiden University, ETH Zurich, QPS (Netherlands), Centre for Human Drug Research, MSD (Netherlands), Quality Positioning Services (Netherlands), Organon (Netherlands)
ORCID: 0000-0001-8447-2934
Observed ORCID: 0000-0001-8447-2934
OpenAlex ID: A5065632651
Abstract of papers
1987 · A. W. T. Konings, H. Joenje, et al. · Pharmacy World & Science · 428
Safety and Tolerability, Pharmacokinetics, and Pharmacodynamics of ACT017, an Antiplatelet GPVI (Glycoprotein VI) Fab: First-in-Human Healthy Volunteer Trial
2019 · Christine Voors-Pette, Kristell Lebozec, et al. · Arteriosclerosis Thrombosis and Vascular Biology · 123
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Development of a simple incubation system for metabolism studies with precision-cut liver slices.
1993 · P Dogterom · Drug Metabolism and Disposition · 105
Examination of Org 26576, an AMPA receptor positive allosteric modulator, in patients diagnosed with major depressive disorder: an exploratory, randomized, double-blind, placebo-controlled trial
2012 · Kari R Nations, Peter Dogterom, et al. · Journal of Psychopharmacology · 75
Application of Absorption Modeling to Predict Bioequivalence Outcome of Two Batches of Etoricoxib Tablets
2014 · Amitava Mitra, Filippos Kesisoglou, et al. · AAPS PharmSciTech · 72
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Effect of a High-Fat Meal on the Pharmacokinetics of 300-Milligram Posaconazole in a Solid Oral Tablet Formulation
2015 · Wendy M. Kersemaekers, Peter Dogterom, et al. · Antimicrobial Agents and Chemotherapy · 65
Cardiotoxicity of Vasodilators and Positive Inotropic/Vasodilating Drugs in Dogs: An Overview
1992 · Peter Dogterom, Gerhard Zbinden, et al. · Critical Reviews in Toxicology · 65
Hepatotoxicity of tetrahydroaminoacridine in isolated rat hepatocytes: Effect of glutathione and vitamin E
1988 · Peter Dogterom, J.Fred Nagelkerke, et al. · Biochemical Pharmacology · 50
Prolonged high intracellular free calcium concentrations induced by ATP are not immediately cytotoxic in isolated rat hepatocytes. Changes in biochemical parameters implicated in cell toxicity
1989 · J F Nagelkerke, P Dogterom, et al. · Biochemical Journal · 42
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Population Pharmacokinetic/Pharmacodynamic Modeling of Glenzocimab (ACT017) a Glycoprotein VI Inhibitor of Collagen‐Induced Platelet Aggregation
2020 · Lionel Renaud, Kristell Lebozec, et al. · The Journal of Clinical Pharmacology · 41
Quantification of asenapine and three metabolites in human plasma using liquid chromatography–tandem mass spectrometry with automated solid‐phase extraction: application to a phase I clinical trial with asenapine in healthy male subjects
2011 · Theo de Boer, Erik Meulman, et al. · Biomedical Chromatography · 41
Inhibition of lipid peroxidation by disulfiram and diethyldithiocarbamate does not prevent hepatotoxin-induced cell death in isolated rat hepatocytes. A study with allyl alcohol, tert-butyl hydroperoxide, diethyl maleate, bromoisovalerylurea and carbon tetrachloride
1988 · Peter Dogterom, J.Fred Nagelkerke, et al. · Chemico-Biological Interactions · 39
Absence of Pharmacokinetic Interactions of the Combined Contraceptive Vaginal Ring NuvaRing?? with Oral Amoxicillin or Doxycycline in Two Randomised Trials
2005 · Peter Dogterom, Michiel W van den Heuvel, et al. · Clinical Pharmacokinetics · 38
Lipid peroxidation-dependent and -independent protein thiol modifications in isolated rat hepatocytes: Differential effects of vitamin E and disulfiram
1989 · Peter Dogterom, Gerard J. Mulder, et al. · Chemico-Biological Interactions · 38
Asenapine Pharmacokinetics in Hepatic and Renal Impairment
2011 · Pierre Peeters, Howard Bockbrader, et al. · Clinical Pharmacokinetics · 36
Troglitazone has no effect on red cell mass or other erythropoietic parameters
1999 · M. M. R. Young, L. Squassante, et al. · European Journal of Clinical Pharmacology · 33
A species comparison of tolbutamide metabolism in precision-cut liver slices from rats and dogs. Qualitative and quantitative sex differences.
1993 · P Dogterom, J Rothuizen · Drug Metabolism and Disposition · 29
Maximum Tolerated Dose Evaluation of the AMPA Modulator Org 26576 in Healthy Volunteers and Depressed Patients: A Summary and Method Analysis of Bridging Research in Support of Phase II Dose Selection
2012 · Kari R. Nations, Roberta Bursi, et al. · Drugs in R&D · 23
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Development and validation of automated SPE‐HPLC‐MS/MS methods for the quantification of asenapine, a new antipsychotic agent, and its two major metabolites in human urine
2012 · Theo de Boer, Erik Meulman, et al. · Biomedical Chromatography · 22
alpha-Bromoisovalerylurea as model substrate for studies on pharmacokinetics of glutathione conjugation in the rat. II. Pharmacokinetics and stereoselectivity of metabolism and excretion in vivo and in the perfused liver.
1986 · J M te Koppele, P Dogterom, et al. · Journal of Pharmacology and Experimental Therapeutics · 22
Comparison of the Pharmacokinetic Profiles of Trientine Tetrahydrochloride and Trientine Dihydrochloride in Healthy Subjects
2021 · Karl Heinz Weiss, Catherine Thompson, et al. · European Journal of Drug Metabolism and Pharmacokinetics · 21
Valproate Reduces the Glucuronidation of Asenapine Without Affecting Asenapine Plasma Concentrations
2011 · Mireille G.F. Gerrits, Rik de Greef, et al. · The Journal of Clinical Pharmacology · 21
Effect of Rifampin‐Mediated OATP1B1 and OATP1B3 Transporter Inhibition on the Pharmacokinetics of the P2Y12 Receptor Antagonist Selatogrel
2020 · Uta Schilling, Jasper Dingemanse, et al. · Clinical and Translational Science · 16
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Translational PK–PD modelling of molecular target modulation for the AMPA receptor positive allosteric modulator Org 26576
2011 · Roberta Bursi, Gul Erdemli, et al. · Psychopharmacology · 16
Asenapine pharmacokinetics and tolerability in a pediatric population
2018 · Peter Dogterom, Robert Riesenberg, et al. · Drug Design Development and Therapy · 13
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Works count: 56
Citation count: 1,593
H-index: 21
I10-index: 29
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