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Sinead A O’Rourke

Observed names: O'Rourke, Sinead, O’Rourke, Sinead A., S.A. O'Rourke, S.A. O'Rourke, Sinead A O'Rourke, Sinead A. O'Rourke, Sinead A. O’Rourke, Sinead O'Rourke
ORCID: 0000-0003-0415-9871
Observed ORCID: 0000-0003-0415-9871
OpenAlex ID: A5065778349
The Nrf2-HO-1 system and inflammaging
2024 · Sinead A. O’Rourke, Lianne C. Shanley, et al. · Frontiers in Immunology · 159
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The Role of Macrophages in the Infarcted Myocardium: Orchestrators of ECM Remodeling
2019 · Sinead A. O'Rourke, Aisling Dunne, et al. · Frontiers in Cardiovascular Medicine · 120
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Cholesterol crystals drive metabolic reprogramming and M1 macrophage polarisation in primary human macrophages
2022 · Sinead A. O'Rourke, Nuno G.B. Neto, et al. · Atherosclerosis · 59
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Non-invasive classification of macrophage polarisation by 2P-FLIM and machine learning
2022 · Nuno G.B. Neto, Sinead A. O’Rourke, et al. · eLife · 33
Macrophage Metabolic Profile is Altered by Hydroxyapatite Particle Size
2022 · Lianne C. Shanley, Olwyn R. Mahon, et al. · Acta Biomaterialia · 29
Mechano-immunomodulation of macrophages influences the regenerative environment of fracture healing through the regulation of angiogenesis and osteogenesis
2025 · S.R. Petrousek, G.S. Kronemberger, et al. · Acta Biomaterialia · 25
Human airway macrophages are metabolically reprogrammed by IFN-γ resulting in glycolysis-dependent functional plasticity
2024 · Donal J Cox, Sarah A Connolly, et al. · eLife · 16
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Staphylococcus aureus suppresses the pentose phosphate pathway in human neutrophils via the adenosine receptor A2aR to enhance intracellular survival
2023 · Emilio G. Vozza, Clíodhna M. Daly, et al. · mBio · 14
Human airway macrophages are metabolically reprogrammed by IFN-γ resulting in glycolysis-dependent functional plasticity
2024 · Donal J Cox, Sarah A Connolly, et al. · eLife · 13
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Type 1 interferons promote Staphylococcus aureus nasal colonization by inducing phagocyte apoptosis
2024 · Emilio G. Vozza, Alanna M. Kelly, et al. · Cell Death Discovery · 13
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The Notch-3 receptor: A molecular switch to tumorigenesis?
2017 · Shakeel Inder, Sinead O'Rourke, et al. · Cancer Treatment Reviews · 13
Electromodulation of human monocyte-derived macrophages drives a regenerative phenotype and impedes inflammation
2025 · Sinead A. O’Rourke, Meenakshi Suku, et al. · Cell Reports Physical Science · 6
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The Trypanosoma brucei-Derived Ketoacids, Indole Pyruvate and Hydroxyphenylpyruvate, Induce HO-1 Expression and Suppress Inflammatory Responses in Human Dendritic Cells
2022 · Hannah K. Fitzgerald, Sinead A. O’Rourke, et al. · Antioxidants · 6
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Human macrophage polarisation and regulation of angiogenesis and osteogenesis is dependent on culture extracellular matrix and dimensionality
2024 · S.R. Petrousek, G.S. Kronemberger, et al. · Biochemical and Biophysical Research Communications · 4
Endogenous drivers of altered immune cell metabolism
2022 · Lianne C Shanley, Hannah K Fitzgerald, et al. · Experimental Biology and Medicine · 4
IFN-γ–induced trained immunity enhances killing of priority pathogens in healthy and genetically vulnerable individuals
2026 · Dearbhla M. Murphy, Isabella Batten, et al. · JCI Insight · 3
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BNT162b2 mRNA vaccination attenuates innate immune function in humans
2025 · Sarah A. Connolly, Aaron Walsh, et al. · Clinical Immunology · 2
Human airway macrophages are metabolically reprogrammed by IFN-γ resulting in glycolysis dependent functional plasticity
2024 · Donal J Cox, Sarah A Connolly, et al. · eLife · 2
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Mechano-Immunomodulation of Macrophages Influences the Regenerative Environment for Bone Repair
2025 · S.R. Petrousek, G.S. Kronemberger, et al. · SSRN Electronic Journal · 1
The Stiffness of Bone Extracellular Matrix Derived Scaffolds Regulates Macrophage Function and Osteogenesis of Mesenchymal Stromal Cells
2026 · Giovanni Gonnella, Sinead A. O’Rourke, et al. · ACS Biomaterials Science & Engineering
Contributors
2025 · G. Abirami, Lais Lima de Castro Abreu, et al. · Elsevier eBooks
Polyphenols and the control of immunometabolism as a pharmacological target
2025 · Gearóid Conlon, Nicole Campbell, et al. · Elsevier eBooks
Author response: Human airway macrophages are metabolically reprogrammed by IFN-γ resulting in glycolysis-dependent functional plasticity
2024 · Donal J Cox, Sarah A Connolly, et al.
Author response: Human airway macrophages are metabolically reprogrammed by IFN-γ resulting in glycolysis dependent functional plasticity
2024 · Donal J Cox, Sarah A Connolly, et al.
Human airway macrophages are metabolically reprogrammed by IFN-γ resulting in glycolysis dependent functional plasticity
2024 · Donal J Cox, Sarah A Connolly, et al. · eLife
Works count: 30
Citation count: 522
H-index: 11
I10-index: 11
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