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Cyril Bařinka

Observed names: Barinka, Cyril, Bařinka, Cyril, C. Barinka, C. Bařinka, Cyril Barinka, Cyril Bařinka, Cyril BaŘinka
Observed institutions: Centre National de la Recherche Scientifique, Johns Hopkins University, Czech Academy of Sciences, Charles University, Johns Hopkins Medicine, Yale University, University of Illinois Chicago, Czech Academy of Sciences, Institute of Biotechnology, Centre de Biophysique Moléculaire, Frederick National Laboratory for Cancer Research, National Cancer Institute, Czech Academy of Sciences, Institute of Organic Chemistry and Biochemistry, Center for Cancer Research, Columbia University
ORCID: 0000-0003-2751-3060
Observed ORCID: 0000-0003-2751-3060
OpenAlex ID: A5066069524
Structure of glutamate carboxypeptidase II, a drug target in neuronal damage and prostate cancer
2006 · Jeroen R Mesters, Cyril Barinka, et al. · The EMBO Journal · 287
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Glutamate Carboxypeptidase II in Diagnosis and Treatment of Neurologic Disorders and Prostate Cancer
2012 · C. Barinka, C. Rojas, et al. · Current Medicinal Chemistry · 201
Interactions between Human Glutamate Carboxypeptidase II and Urea-Based Inhibitors: Structural Characterization
2008 · Cyril Barinka, Youngjoo Byun, et al. · Journal of Medicinal Chemistry · 184
Development of Multifunctional Histone Deacetylase 6 Degraders with Potent Antimyeloma Activity
2019 · Hao Wu, Ka Yang, et al. · Journal of Medicinal Chemistry · 181
Selective HDAC6 inhibitors improve anti-PD-1 immune checkpoint blockade therapy by decreasing the anti-inflammatory phenotype of macrophages and down-regulation of immunosuppressive proteins in tumor cells
2019 · Tessa Knox, Eva Sahakian, et al. · Scientific Reports · 178
Histone Deacetylase 11 Is a Fatty-Acid Deacylase
2018 · Zsofia Kutil, Zora Novakova, et al. · ACS Chemical Biology · 178
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Glu-Ureido–Based Inhibitors of Prostate-Specific Membrane Antigen: Lessons Learned During the Development of a Novel Class of Low-Molecular-Weight Theranostic Radiotracers
2017 · Klaus Kopka, Martina Benešová, et al. · Journal of Nuclear Medicine · 164
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A Remote Arene-Binding Site on Prostate Specific Membrane Antigen Revealed by Antibody-Recruiting Small Molecules
2010 · Andrew X. Zhang, Ryan P. Murelli, et al. · Journal of the American Chemical Society · 164
Calcium-Driven Folding of RTX Domain β-Rolls Ratchets Translocation of RTX Proteins through Type I Secretion Ducts
2016 · Ladislav Bumba, Jiri Masin, et al. · Molecular Cell · 162
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Expression of glutamate carboxypeptidase II in human brain
2006 · P. Šácha, J. Zámečník, et al. · Neuroscience · 133
Substrate specificity, inhibition and enzymological analysis of recombinant human glutamate carboxypeptidase II
2002 · Cyril Barinka, Markéta Rinnová, et al. · Journal of Neurochemistry · 123
Author Correction: Selective HDAC6 inhibitors improve anti-PD-1 immune checkpoint blockade therapy by decreasing the anti-inflammatory phenotype of macrophages and down-regulation of immunosuppressive proteins in tumor cells
2019 · Tessa Knox, Eva Sahakian, et al. · Scientific Reports · 119
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Structural Basis of Interaction between Urokinase-type Plasminogen Activator and its Receptor
2006 · Cyril Barinka, Graham Parry, et al. · Journal of Molecular Biology · 116
Identification of the N‐glycosylation sites on glutamate carboxypeptidase II necessary for proteolytic activity
2004 · Cyril Barinka, Pavel Šácha, et al. · Protein Science · 108
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Structural Basis of Interactions between Human Glutamate Carboxypeptidase II and Its Substrate Analogs
2008 · Cyril Barinka, Klara Hlouchova, et al. · Journal of Molecular Biology · 104
Structural and in Vivo Characterization of Tubastatin A, a Widely Used Histone Deacetylase 6 Inhibitor
2020 · Sida Shen, Michal Svoboda, et al. · ACS Medicinal Chemistry Letters · 91
Mitochondria-adaptor TRAK1 promotes kinesin-1 driven transport in crowded environments
2020 · Verena Henrichs, Lenka Grycova, et al. · Nature Communications · 90
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Structural Insight into the Pharmacophore Pocket of Human Glutamate Carboxypeptidase II
2007 · Cyril Bařinka, Miroslava Rovenská, et al. · Journal of Medicinal Chemistry · 87
Discovery of a New Isoxazole-3-hydroxamate-Based Histone Deacetylase 6 Inhibitor SS-208 with Antitumor Activity in Syngeneic Melanoma Mouse Models
2019 · Sida Shen, Melissa Hadley, et al. · Journal of Medicinal Chemistry · 85
A prostate-specific membrane antigen activated molecular rotor for real-time fluorescence imaging
2021 · Jingming Zhang, Anastasia Rakhimbekova, et al. · Nature Communications · 84
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Mouse brain serine racemase catalyzes specific elimination of L ‐serine to pyruvate
2002 · Kvido Střı́šovský, Jana Jirásková, et al. · FEBS Letters · 84
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Human histone deacetylase 6 shows strong preference for tubulin dimers over assembled microtubules
2017 · Lubica Skultetyova, Kseniya Ustinova, et al. · Scientific Reports · 83
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Brain Penetrable Histone Deacetylase 6 Inhibitor SW-100 Ameliorates Memory and Learning Impairments in a Mouse Model of Fragile X Syndrome
2018 · Alan P. Kozikowski, Sida Shen, et al. · ACS Chemical Neuroscience · 81
Bioisosterism of urea-based GCPII inhibitors: Synthesis and structure–activity relationship studies
2009 · Haofan Wang, Youngjoo Byun, et al. · Bioorganic & Medicinal Chemistry Letters · 81
Prostate-specific membrane antigen (PSMA)-mediated laminin proteolysis generates a pro-angiogenic peptide
2016 · Rebecca E. Conway, Camilo Rojas, et al. · Angiogenesis · 76
Works count: 204
Citation count: 5,497
H-index: 41
I10-index: 91
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