Author

Eric Gaukel

Observed names: ERIC GAUKEL, Eric G Gaukel, Gaukel, Eric

Institution: Roivant Sciences (United States)

Observed institutions: Scynexis (United States), Roivant Sciences (United States)

OpenAlex ID: A5066257193

SCYX-7158, an Orally-Active Benzoxaborole for the Treatment of Stage 2 Human African Trypanosomiasis

2011 · Robert T. Jacobs, Bakela Nare, et al. · PLoS neglected tropical diseases · 314

Discovery of Novel Orally Bioavailable Oxaborole 6-Carboxamides That Demonstrate Cure in a Murine Model of Late-Stage Central Nervous System African Trypanosomiasis

2010 · Bakela Nare, Stephen Wring, et al. · Antimicrobial Agents and Chemotherapy · 106

Benzoxaboroles: A New Class of Potential Drugs for Human African Trypanosomiasis

2011 · Robert T Jacobs, Jacob J Plattner, et al. · Future Medicinal Chemistry · 93

Topical Treatment for Cutaneous Leishmaniasis: Dermato-Pharmacokinetic Lead Optimization of Benzoxaboroles

2018 · Katrien Van Bocxlaer, Eric Gaukel, et al. · Antimicrobial Agents and Chemotherapy · 70

Pharmacokinetics and pharmacodynamics utilizing unbound target tissue exposure as part of a disposition-based rationale for lead optimization of benzoxaboroles in the treatment of Stage 2 Human African Trypanosomiasis

2013 · STEPHEN WRING, ERIC GAUKEL, et al. · Parasitology · 40

Assessment of a pretomanid analogue library for African trypanosomiasis: Hit-to-lead studies on 6-substituted 2-nitro-6,7-dihydro-5H-imidazo[2,1-b][1,3]thiazine 8-oxides

2017 · Andrew M. Thompson, Andrew J. Marshall, et al. · Bioorganic & Medicinal Chemistry Letters · 26

SAR of 2-amino and 2,4-diamino pyrimidines with in vivo efficacy against Trypanosoma brucei

2011 · Joe B. Perales, Jennifer Freeman, et al. · Bioorganic & Medicinal Chemistry Letters · 10

SCY-641 - A Water-Soluble Cyclophilin Inhibitor for the Treatment of Dry Eye Disease

2011 · Michael Peel, Andrew Scribner, et al. · Investigative Ophthalmology & Visual Science · 3

Pharmacokinetics and tissue distribution of RVT-801, a recombinant human acid ceramidase, at efficacious doses in a murine model of Farber disease

2018 · Eric Gaukel, Christine Coquery, et al. · Molecular Genetics and Metabolism · 1

Efficacy and Pharmacokinetics of SCYX-7158 (AN5568): a Novel and Potent Oxaborole-6-Carboxamide Selected as a Pre-Clinical Candidate for Once-Daily Oral Treatment for Stage 2 Human African Trypanosomiasis.

2009 · Robert M. J. Jacobs, Bakela Nare, et al. · 1

1212 AFVT-2101, an innate immune-cell engager that selectively targets FOLR1 expressing tumor cells to safely harness potent anti-cancer responses

2022 · Ahmad Trad, Michael Tomaszowski, et al. · Journal for ImmunoTherapy of Cancer

Evaluation of efficacy and safety of a novel gene therapy drug (ARU-2801) for hypophosphatasia in non-human primates

2022 · Mohammad Shadid, Eric Gaukel, et al. · Endocrine Abstracts

Prediction of the human equivalent dose (HED) of RVT-801, a recombinant human acid ceramidase, for the treatment of Farber disease

2018 · Eric Gaukel, Christine Coquery, et al. · Molecular Genetics and Metabolism

SCYX-7158 (AN5568): CNS Exposure Predicted from First-in-Human Clinical Studies Indicates a Single Oral Dose Treatment is Possible for Sterile Cures of Stage 2 Human African Trypanosomiasis

2013 · Wring, Stephen, Gaukel, Eric, et al.

SCYX 7158: chemistry background and new findings.

2010 · Robert T. Jacobs, B. Nare, et al.

Works count: 15

Citation count: 664

H-index: 7

I10-index: 7