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Author

Gianluca Caprini

Observed names: Caprini, Gianluca, G. Caprini
Institution: Italfarmaco (Italy)
ORCID: 0000-0001-7318-6174
Observed ORCID: 0000-0001-7318-6174
OpenAlex ID: A5066267299
Novel Benzohydroxamate-Based Potent and Selective Histone Deacetylase 6 (HDAC6) Inhibitors Bearing a Pentaheterocyclic Scaffold: Design, Synthesis, and Biological Evaluation
2019 · Barbara Vergani, Giovanni Sandrone, et al. · Journal of Medicinal Chemistry · 57
Difluoromethyl-1,3,4-oxadiazoles are slow-binding substrate analog inhibitors of histone deacetylase 6 with unprecedented isotype selectivity
2022 · Edoardo Cellupica, Gianluca Caprini, et al. · Journal of Biological Chemistry · 48
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Ferredoxin-NADP+ Reductase and Ferredoxin of the Protozoan Parasite Toxoplasma gondii Interact Productivelyin Vitro and in Vivo
2002 · Vittorio Pandini, Gianluca Caprini, et al. · Journal of Biological Chemistry · 44
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Kinetic and spectroscopic characterization of the putative monooxygenase domain of human MICAL-1
2011 · Daniela Zucchini, Gianluca Caprini, et al. · Archives of Biochemistry and Biophysics · 37
Novel HDAC inhibitors exhibit pre-clinical efficacy in lymphoma models and point to the importance ofCDKN1Aexpression levels in mediating their anti-tumor response
2014 · Afua Adjeiwaa Mensah, Ivo Kwee, et al. · Oncotarget · 35
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Role of Fluorination in the Histone Deacetylase 6 (HDAC6) Selectivity of Benzohydroxamate-Based Inhibitors
2021 · Giovanni Sandrone, Cyprian D. Cukier, et al. · ACS Medicinal Chemistry Letters · 32
The Subnanometer Resolution Structure of the Glutamate Synthase 1.2-MDa Hexamer by Cryoelectron Microscopy and Its Oligomerization Behavior in Solution
2008 · Magali Cottevieille, Eric Larquet, et al. · Journal of Biological Chemistry · 31
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l ‐Lactate dehydrogenation in flavocytochrome b2: A first principles molecular dynamics study
2009 · Gloria Tabacchi, Daniela Zucchini, et al. · FEBS Journal · 22
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A single in vivo‐selected point mutation in the active center of Toxoplasma gondii ferredoxin‐NADP+ reductase leads to an inactive enzyme with greatly enhanced affinity for ferredoxin
2004 · Nadine Thomsen-Zieger, Vittorio Pandini, et al. · FEBS Letters · 16
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Mechanistic and Structural Insights on Difluoromethyl-1,3,4-oxadiazole Inhibitors of HDAC6
2024 · Edoardo Cellupica, Aureliano Gaiassi, et al. · International Journal of Molecular Sciences · 15
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Roles of the Species-Specific Subdomain and the N-Terminal Peptide of Toxoplasma gondii Ferredoxin-NADP+ Reductase in Ferredoxin Binding
2006 · Vittorio Pandini, Gianluca Caprini, et al. · Biochemistry · 8
The Importance of the “Time Factor” for the Evaluation of Inhibition Mechanisms: The Case of Selected HDAC6 Inhibitors
2023 · Edoardo Cellupica, Gianluca Caprini, et al. · Biology · 7
Epigenetic-based cancer therapeutics: new potential HDAC8 inhibitors
2020 · Malihe Hassanzadeh, Shabnam Mahernia, et al. · Journal of Biomolecular Structure and Dynamics · 7
Abstract 1358: The selective HDAC6 inhibitor ITF3756 stimulates an antitumor immune response and leads to tumor regression in combination with anti CTLA-4 antibody in a colon carcinoma murine model
2022 · Gianluca Fossati, Chiara Ripamonti, et al. · Cancer Research · 1
The plant-type ferredoxin-NADP(+) reductase of the protozoan parasite Toxoplasma gondii
2002 · V. Pandini, Gianluca Caprini, et al. · 1
Methods for the kinetic analysis of time-dependent HDAC6 inhibitors
2026 · Edoardo Cellupica, Gianluca Fossati, et al. · Methods in enzymology on CD-ROM/Methods in enzymology
Abstract A129: Novel histone deacetylase inhibitors ITF-A and ITF-B exhibit efficacy in preclinical models of mature B-cell lymphomas.
2013 · Afua A. Mensah, Eugenio Gaudio, et al. · Molecular Cancer Therapeutics
Production and characterization of the monoxygenase domain of human MICAL, a multi domain signaling flavoprotein
2010 · D. Zucchini, Gianluca Caprini, et al.
Studies on the heterologous production of human Seladin-1/DHCR24, a novel antiapoptotic factor
2010 · D. Zucchini, Gianluca Caprini, et al.
Production and characterization of the monoxygenase domain of human MICAL, a multidomain signaling flavoprotein
2010 · Gianluca Caprini, D. Zucchini, et al.
Investigation of the structural properties and oligomerization state of the complex enzyme glutamate synthase by atomic force microscopy
2008 · Marco Indrieri, Gianluca Caprini, et al.
On the Mechanism of L-lactate Oxidation Catalyzed by Flavocytochrome B2: a Combined First Principle Molecular Dynamics and Site Directed Mutagenesis Study
2008 · D. Zucchini, Gianluca Caprini, et al.
Glutamate synthase: self-regulation and oligomeric structure
2008 · Vanoni, Maria A., Curti, Bruno, et al. · HAL
The 9.5 a Resolution Structure of Glutamate Synthase From Cryo-electron Microscopy and Its Oligomerization Behavior in Solution: Functional Implications.
2007 · M. Cottevieille, E. Larquet, et al. · Worldwide Protein Data Bank
Structural analysis of Azospirillum brasilense glumate synthase
2007 · Gianluca Caprini, M. Cottevieille, et al.
Works count: 32
Citation count: 361
H-index: 10
I10-index: 10
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