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Mia Jans
Observed name:
Jans, Mia
Institution:
Galapagos (Belgium)
Observed institution:
Galapagos (Belgium)
ORCID:
0009-0003-4902-7677
Observed ORCID:
0009-0003-4902-7677
OpenAlex ID:
A5066789836
Arrayed adenoviral expression libraries for functional screening
2002
·
Frits Michiels
, Helmuth van Es
, et al.
·
Nature Biotechnology
·
86
Discovery ofN-(3-Carbamoyl-5,5,7,7-tetramethyl-5,7-dihydro-4H-thieno[2,3-c]pyran-2-yl)-lH-pyrazole-5-carboxamide (GLPG1837), a Novel Potentiator Which Can Open Class III Mutant Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Channels to a High Extent
2017
·
Steven E. Van der Plas
, Hans Kelgtermans
, et al.
·
Journal of Medicinal Chemistry
·
65
Discovery, Structure–Activity Relationship, and Binding Mode of an Imidazo[1,2-a]pyridine Series of Autotaxin Inhibitors
2017
·
Agnès Joncour
, Nicolas Desroy
, et al.
·
Journal of Medicinal Chemistry
·
65
Identification and Characterization of Novel CFTR Potentiators
2018
·
Maarten Gees
, Sara Musch
, et al.
·
Frontiers in Pharmacology
·
47
PDF
Identification of GLPG/ABBV-2737, a Novel Class of Corrector, Which Exerts Functional Synergy With Other CFTR Modulators
2019
·
Gert de Wilde
, Maarten Gees
, et al.
·
Frontiers in Pharmacology
·
41
PDF
Discovery of the S1P2 Antagonist GLPG2938 (1-[2-Ethoxy-6-(trifluoromethyl)-4-pyridyl]-3-[[5-methyl-6-[1-methyl-3-(trifluoromethyl)pyrazol-4-yl]pyridazin-3-yl]methyl]urea), a Preclinical Candidate for the Treatment of Idiopathic Pulmonary Fibrosis
2021
·
Oscar Mammoliti
, Adeline Palisse
, et al.
·
Journal of Medicinal Chemistry
·
34
Discovery and Optimization of Orally Bioavailable Phthalazone and Cinnolone Carboxylic Acid Derivatives as S1P2 Antagonists against Fibrotic Diseases
2021
·
Oscar Mammoliti
, Koen Jansen
, et al.
·
Journal of Medicinal Chemistry
·
22
Discovery of GLPG2737, a Potent Type 2 Corrector of CFTR for the Treatment of Cystic Fibrosis in Combination with a Potentiator and a Type 1 Co-corrector
2024
·
Mathieu Pizzonero
, Rhalid Akkari
, et al.
·
Journal of Medicinal Chemistry
·
13
Human skin stem cell-derived hepatic cells as in vitro drug discovery model for insulin-driven de novo lipogenesis
2023
·
Karolien Buyl
, Martine Vrints
, et al.
·
European Journal of Pharmacology
·
5
PDF
Erratum: Corrigendum: Arrayed adenoviral expression libraries for functional screening
2003
·
Frits Michiels
, Helmuth van Es
, et al.
·
Nature Biotechnology
·
5
HBsAg Suppression by a New Series of HBV RNA Destabilizers: Discovery and Effects on In Vitro Neurite Outgrowth
2026
·
Jacques Huck
, Caroline Joannesse
, et al.
·
Journal of Medicinal Chemistry
·
3
Structure activity relationship exploration of imidazo[1,2-a]pyridine series to reverse isoform selectivity and identify potent SIK1 selective inhibitors
2025
·
Christophe Peixoto
, Elsa De Lemos
, et al.
·
Bioorganic & Medicinal Chemistry Letters
·
3
Structure–Activity Relationship Guided Scaffold Hopping Resulted in the Identification of GLPG4970, a Highly Potent Dual SIK2/SIK3 Inhibitor
2025
·
Hans Kelgtermans
, Maxim De Wachter
, et al.
·
Journal of Medicinal Chemistry
·
3
Discovery and Characterization of GLPG3808, a PAPD5/7 Inhibitor for Suppression of Hepatitis B Viral Infections
2026
·
Oscar Mammoliti
, Adeline Palisse
, et al.
·
Journal of Medicinal Chemistry
·
2
Pharmacological Characterization of GLPG3667, a Tyrosine Kinase 2-Selective Inhibitor, for the Treatment of Inflammatory and Autoimmune Diseases
2026
·
Céline Cottereaux
, May-Linda Lepage
, et al.
·
Inflammation
CCDC 2122384: Experimental Crystal Structure Determination
2021
·
Mammoliti, Oscar
, Jansen, Koen
, et al.
·
The Cambridge Structural Database
CCDC 2122349: Experimental Crystal Structure Determination
2021
·
Mammoliti, Oscar
, Jansen, Koen
, et al.
·
The Cambridge Structural Database
Correction to Discovery, Structure–Activity Relationship, and Binding Mode of an Imidazo[1,2-a]pyridine Series of Autotaxin Inhibitors
2018
·
Agnès Joncour
, Nicolas Desroy
, et al.
·
Journal of Medicinal Chemistry
PDF
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Works count:
18
Citation count:
394
H-index:
8
I10-index:
8
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