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Eline Sijbesma

Observed names: E. Sijbesma, Sijbesma, E Eline, Sijbesma, Eline
ORCID: 0000-0002-4837-7574
Observed ORCID: 0000-0002-4837-7574
OpenAlex ID: A5066822642
Modulators of 14-3-3 Protein–Protein Interactions
2017 · Loes M. Stevers, Eline Sijbesma, et al. · Journal of Medicinal Chemistry · 292
Stabilization of protein-protein interactions in drug discovery
2017 · Sebastian A. Andrei, Eline Sijbesma, et al. · Expert Opinion on Drug Discovery · 168
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Site-Directed Fragment-Based Screening for the Discovery of Protein–Protein Interaction Stabilizers
2019 · Eline Sijbesma, Kenneth K. Hallenbeck, et al. · Journal of the American Chemical Society · 112
Early in-situ cellularization of a supramolecular vascular graft is modified by synthetic stromal cell-derived factor-1α derived peptides
2015 · Dimitri E.P. Muylaert, Geert C. van Almen, et al. · Biomaterials · 109
Structure-based evolution of a promiscuous inhibitor to a selective stabilizer of protein–protein interactions
2020 · Eline Sijbesma, Emira Visser, et al. · Nature Communications · 74
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A Systematic Approach to the Discovery of Protein–Protein Interaction Stabilizers
2023 · Dyana N. Kenanova, Emira J. Visser, et al. · ACS Central Science · 60
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Modulating protein–protein interaction networks in protein homeostasis
2019 · Mengqi Zhong, Gregory M Lee, et al. · Current Opinion in Chemical Biology · 58
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Rationally Designed Semisynthetic Natural Product Analogues for Stabilization of 14‐3‐3 Protein–Protein Interactions
2018 · Sebastian A. Andrei, Pim de Vink, et al. · Angewandte Chemie International Edition · 58
Identification of Two Secondary Ligand Binding Sites in 14-3-3 Proteins Using Fragment Screening
2017 · Eline Sijbesma, Lukasz Skora, et al. · Biochemistry · 46
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Fluorescence Anisotropy-Based Tethering for Discovery of Protein–Protein Interaction Stabilizers
2020 · Eline Sijbesma, Bente A. Somsen, et al. · ACS Chemical Biology · 41
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A Liquid Chromatography/Mass Spectrometry Method for Screening Disulfide Tethering Fragments
2017 · Kenneth K Hallenbeck, Julia L. Davies, et al. · SLAS DISCOVERY · 32
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From Tethered to Freestanding Stabilizers of 14‐3‐3 Protein‐Protein Interactions through Fragment Linking
2023 · Emira J. Visser, Priyadarshini Jaishankar, et al. · Angewandte Chemie International Edition · 26
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Exploration of a 14-3-3 PPI Pocket by Covalent Fragments as Stabilizers
2021 · Eline Sijbesma, Kenneth K. Hallenbeck, et al. · ACS Medicinal Chemistry Letters · 21
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A Supramolecular Stabilizer of the 14‐3‐3ζ/ERα Protein‐Protein Interaction with a Synergistic Mode of Action
2019 · Alba Gigante, Eline Sijbesma, et al. · Angewandte Chemie International Edition · 17
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Molecular basis and dual ligand regulation of tetrameric estrogen receptor α/14-3-3ζ protein complex
2023 · Bente A. Somsen, Eline Sijbesma, et al. · Journal of Biological Chemistry · 16
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Arginine mimetic appended peptide-based probes for fluorescence turn-on detection of 14-3-3 proteins
2019 · Debabrata Maity, Alba Gigante, et al. · Organic & Biomolecular Chemistry · 12
Rationally Designed Semisynthetic Natural Product Analogues for Stabilization of 14‐3‐3 Protein–Protein Interactions
2018 · Sebastian A. Andrei, Pim de Vink, et al. · Angewandte Chemie · 5
From Tethered to Freestanding Stabilizers of 14‐3‐3 Protein‐Protein Interactions through Fragment Linking
2023 · Emira J. Visser, Priyadarshini Jaishankar, et al. · Angewandte Chemie · 1
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Co-soaked stabilizers for ERa - 14-3-3 interaction (844_AZ210)
2023 · Visser, Emira J., Jaishankar, Priyadarshini, et al. · TU/e Research Portal
single soak stabilizer for ERa - 14-3-3 interaction (AZ555)
2023 · Visser, Emira J., Jaishankar, Priyadarshini, et al. · TU/e Research Portal
Small molecule amidine soak in 14-3-3/ERa (AZ132)
2023 · Visser, Emira J., Jaishankar, Priyadarshini, et al. · TU/e Research Portal
single soak stabilizer for ERa - 14-3-3 interaction (AZ275)
2023 · Visser, Emira J., Jaishankar, Priyadarshini, et al. · TU/e Research Portal
Small molecule stabilizer (compound 8) for C-RAF and 14-3-3
2023 · Kenanova, Dyana N., Visser, Emira J., et al. · TU/e Research Portal
Small molecule stabilizer (compound 2) for FOXO1 and 14-3-3
2023 · Kenanova, Dyana N., Visser, Emira J., et al. · TU/e Research Portal
small molecule stabilizer (compound 1) for C-RAF pS259 and 14-3-3
2023 · Kenanova, Dyana N., Visser, Emira J., et al. · TU/e Research Portal
Works count: 66
Citation count: 1,148
H-index: 15
I10-index: 16
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